ZFIN Person: Hess, Isabell

ZFIN ID: ZDB-PERS-060908-14

Hess, Isabell

Email:	hess@immunbio.mpg.de
URL:
Affiliation:
Address:	Institute of Toxicology and Genetics Forschungszentrum Karlsruhe Postfach 3640 Karlsruhe, D-76021 Germany
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BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Hess, I., Sagar, ., O Meara, C., Grün, D., Schorpp, M., Boehm, T. (2022) Stage-specific and cell type-specific requirements of ikzf1 during haematopoietic differentiation in zebrafish. Scientific Reports. 12:2140121401

Lawir, D.F., Hess, I., Sikora, K., Iwanami, N., Siamishi, I., Schorpp, M., Boehm, T. (2019) Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. Proceedings of the National Academy of Sciences of the United States of America. 116(52):26759-26767

Yakulov, T.A., Todkar, A.P., Slanchev, K., Wiegel, J., Bona, A., Groß, M., Scholz, A., Hess, I., Wurditsch, A., Grahammer, F., Huber, T.B., Lecaudey, V., Bork, T., Hochrein, J., Boerries, M., Leenders, J., de Tullio, P., Jouret, F., Kramer-Zucker, A., Walz, G. (2018) CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury. Nature communications. 9:3660

Tenno, M., Kojo, S., Lawir, D.F., Hess, I., Shiroguchi, K., Ebihara, T., Endo, T.A., Muroi, S., Satoh, R., Kawamoto, H., Boehm, T., Taniuchi, I. (2018) Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. The Journal of experimental medicine. 215(2):595-610

Iwanami, N., Hess, I., Schorpp, M., Boehm, T. (2017) Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells. Methods in cell biology. 138:151-161

Iwanami, N., Sikora, K., Richter, A.S., Mönnich, M., Guerri, L., Soza-Ried, C., Lawir, D.F., Mateos, F., Hess, I., O'Meara, C.P., Schorpp, M., Boehm, T. (2016) Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Cell Reports. 17:2259-2270

Hess, I., Boehm, T. (2016) Stable multilineage xenogeneic replacement of definitive hematopoiesis in adult zebrafish. Scientific Reports. 6:19634

Swann, J.B., Weyn, A., Nagakubo, D., Bleul, C.C., Toyoda, A., Happe, C., Netuschil, N., Hess, I., Haas-Assenbaum, A., Taniguchi, Y., Schorpp, M., Boehm, T. (2014) Conversion of the thymus into a bipotent lymphoid organ by replacement of FOXN1 with its paralog, FOXN4. Cell Reports. 8:1184-97

Hess, I., Iwanami, N., Schorpp, M., and Boehm, T. (2013) Zebrafish model for allogeneic hematopoietic cell transplantation not requiring preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 110(11):4327-32

Hess, I., and Boehm, T. (2012) Intravital Imaging of Thymopoiesis Reveals Dynamic Lympho-Epithelial Interactions. Immunity. 36(2):298-309

Iwanami, N., Mateos, F., Hess, I., Riffel, N., Soza-Ried, C., Schorpp, M., and Boehm, T. (2011) Genetic Evidence for an Evolutionarily Conserved Role of IL-7 Signaling in T Cell Development of Zebrafish. Journal of immunology (Baltimore, Md. : 1950). 186(12):7060-6

Soza-Ried, C., Hess, I., Netuschil, N., Schorpp, M., and Boehm, T. (2010) Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved. Proceedings of the National Academy of Sciences of the United States of America. 107(40):17304-17308

Mönnich, M., Hess, I., Wiest, W., Bachrati, C., Hickson, I.D., Schorpp, M., and Boehm, T. (2010) Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha. European journal of immunology. 40(9):2379-2384

Bajoghli, B., Aghaallaei, N., Hess, I., Rode, I., Netuschil, N., Tay, B.H., Venkatesh, B., Yu, J.K., Kaltenbach, S.L., Holland, N.D., Diekhoff, D., Happe, C., Schorpp, M., and Boehm, T. (2009) Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates. Cell. 138(1):186-197

Pannicke, U., Hönig, M., Hess, I., Friesen, C., Holzmann, K., Rump, E.M., Barth, T.F., Rojewski, M.T., Schulz, A., Boehm, T., Friedrich, W., and Schwarz, K. (2009) Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. Nature Genetics. 41(1):101-105

Rastegar, S., Hess, I., Dickmeis, T., Nicod, J.C., Ertzer, R., Hadzhiev, Y., Thies, W.G., Scherer, G., and Strähle, U. (2008) The words of the regulatory code are arranged in a variable manner in highly conserved enhancers. Developmental Biology. 318(2):366-377

NON-ZEBRAFISH PUBLICATIONS