ZFIN ID: ZDB-PERS-060807-4
Wang, Yuexiang
Email: yxwang76@shmu.edu.cn
Affiliation: Song Lab
Address: Department of Molecular Genetics, Shanghai Medical School Key Laboratory of Molecular Medicine, Ministry of Education Fudan University 138 Yi Xueyuan Road Shanghai, 200032 China
Country: China
Phone: +86 21 5423 7440
Fax: +86 21 6403 3738

I am particularly interested in the roles of BMP2 and MEF2A signaling pathways in zebrafish cardiovascular system and somite development. We try to get new insights into the prevention and treatment of related human diseases.

Jiang, Q., Liu, D., Sun, S., Hu, J., Tan, L., Wang, Y., Gui, Y., Yu, M., and Song, H. (2010) Critical role of connexin43 in zebrafish late primitive and definitive hematopoiesis. Fish physiology and biochemistry. 36(4):945-951
Zhang, L.F., Gui, Y.H., Wang, Y.X., Jiang, Q., and Song, H.Y. (2010) Effect of Tbx1 knock-down on cardiac performance in zebrafish. Chinese Medical Journal. 123(9):1182-1189
Chen, H., Hu, J., Yang, J., Wang, Y., Xu, H., Jiang, Q., Gong, Y., Gu, Y., and Song, H. (2010) Generation of a fluorescent transgenic zebrafish for detection of environmental estrogens. Aquatic toxicology (Amsterdam, Netherlands). 96(1):53-61
Jiang, Q., Liu, D., Gong, Y., Wang, Y., Sun, S., Gui, Y., and Song, H. (2009) yap is required for the development of brain, eyes, and neural crest in zebrafish. Biochemical and Biophysical Research Communications. 384(1):114-119
Sun, S., Gui, Y., Wang, Y., Qian, L., Liu, X., Jiang, Q., and Song, H. (2009) Effects of methotrexate on the developments of heart and vessel in zebrafish. Acta biochimica et biophysica Sinica. 41(1):86-96
Xu, H., Yang, J., Wang, Y., Jiang, Q., Chen, H., and Song, H. (2008) Exposure to 17α-ethynylestradiol impairs reproductive functions of both male and female zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 88(1):1-8
Sun, S.N., Gui, Y.H., Wang, Y.X., Qian, L.X., Jiang, Q., Liu, D., and Song, H.Y. (2007) Effect of dihydrofolate reductase gene knock-down on the expression of heart and neural crest derivatives expressed transcript 2 in zebrafish cardiac development. Chinese Medical Journal. 120(13):1166-1171
Wang, Y.X., Qian, L.X., Liu, D., Yao, L.L., Jiang, Q., Yu, Z., Gui, Y.H., Zhong, T.P., and Song, H.Y. (2007) Bone morphogenetic protein-2 acts upstream of myocyte-specific enhancer factor 2a to control embryonic cardiac contractility. Cardiovascular research. 74(2):290-303
Wang, Y., Qian, L., Dong, Y., Jiang, Q., Gui, Y., Zhong, T.P., and Song, H. (2006) Myocyte-specific enhancer factor 2A is essential for zebrafish posterior somite development. Mechanisms of Development. 123(10):783-791
Zhang, L., Zhong, T., Wang, Y., Jiang, Q., Song, H., and Gui, Y. (2006) TBX1, a DiGeorge syndrome candidate gene, is inhibited by retinoic acid. The International journal of developmental biology. 50(1):55-61
Qian, L., Wang, Y., Jiang, Q., Zhong, T., and Song, H. (2005) Ethanol disrupts the formation of hypochord and dorsal aorta during the development of embryonic zebrafish. Science in China. Series C, Life sciences. 48(6):608-615
Wang, Y.X., Qian, L.X., Yu, Z., Jiang, Q., Dong, Y.X., Liu, X.F., Xin-Ying, Y., Zhong, T.P., and Song, H.Y. (2005) Requirements of myocyte-specific enhancer factor 2A in zebrafish cardiac contractility. FEBS letters. 579(21):4843-4850
Wang, Y., Zhong, T., Qian, L., Dong, Y., Jiang, Q., Tan, L., and Song, H. (2005) Wortmannin induces zebrafish cardia bifida through a mechanism independent of phosphoinositide 3-kinase and myosin light chain kinase. Biochemical and Biophysical Research Communications. 331(1):303-308

Wang, Y.X., Yang, J., Ma, C.G., Yang, X.Y., Song, H.Y. (2003) VEGF121 cDNA gene transfer and expression in Vitro. Prog. Biochem. Biophys. 30(4):612-616.

Wang, Y.X., Guan, X.Q., Yang, J., Mo, W., Song, H.Y. (2002) Molecular Cloning, Expression and characterization of recombinant human vascular endothelial growth factor 121. Prog. Biochem. Biophys. 29(3): 444-448.