ZFIN ID: ZDB-PERS-060727-9
Sachidanandan, Chetana
Email: chetana@igib.in
URL: http://chemgen.igib.in/
Affiliation: Sachidanandan Lab
Address: Chetana Sachidanandan, PhD. Scientist, CSIR-Institute of Genomics & Integrative Biology (CSIR-IGIB) & Assistant Professor, Academy of Scientific and Innovative Research (AcSIR) CSIR-IGIB South Campus Mathura Road, Near Sukhdev Vihar, New Delhi 110025
Country: India
Phone: +91-11-29879-105
Fax:
ORCID ID: 0000-0003-2109-4774


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Lone, B.A., Siraj, F., Sharma, I., Verma, S., Karna, S.K.L., Ahmad, F., Nagar, P., Sachidanandan, C., Pokharel, Y.R. (2023) Non-POU Domain-Containing Octomer-Binding (NONO) protein expression and stability promotes the tumorigenicity and activation of Akt/MAPK/β-catenin pathways in human breast cancer cells. Cell communication and signaling : CCS. 21:157157
Singh, M.K., Yadav, R., Bhaskar, A.K., Sengupta, S., Sachidanandan, C. (2022) A diet-independent zebrafish model for NAFLD recapitulates patient lipid profiles and offers a system for small molecule screening. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1868(1):159246
Jagtap, U., Basu, S., Lokhande, L., Bharti, N., Sachidanandan, C. (2022) BML-257, a Small Molecule that Protects against Drug-Induced Liver Injury in Zebrafish. Chemical Research in Toxicology. 35(8):1393-1399
Singh, M.K., Jayarajan, R., Varshney, S., Upadrasta, S., Singh, A., Yadav, R., Scaria, V., Sengupta, S., Shanmugam, D., Shalimar, ., Sivasubbu, S., Gandotra, S., Sachidanandan, C. (2021) Chronic systemic exposure to IL6 leads to deregulation of glycolysis and fat accumulation in the zebrafish liver. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1866(5):158905
Jagtap, U., Sivadas, A., Basu, S., Verma, A., Sivasubbu, S., Scaria, V., Sachidanandan, C. (2019) A Temporal Map of Gene Expression Pattern During Zebrafish Liver Regeneration. Zebrafish. 17(1):1-10
Asad, Z., Sachidanandan, C. (2019) Chemical screens in a zebrafish model of CHARGE syndrome identifies small molecules that ameliorates disease like phenotypes in embryo. European Journal of Medical Genetics. 63(2):103661
Basu, S., Jalodia, K., Ranjan, S., Yeh, J.J., Peterson, R.T., Sachidanandan, C. (2018) Small molecule inhibitors of NFkB reverse iron overload and hepcidin deregulation in a zebrafish model for Hereditary Hemochromatosis Type 3. ACS Chemical Biology. 13(8):2143-2152
Babu, A., Kamaraj, M., Basu, M., Mukherjee, D., Kapoor, S., Ranjan, S., Swamy, M.M., Kaypee, S., Scaria, V., Kundu, T.K., Sachidanandan, C. (2018) Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi syndrome in zebrafish. Biochimica et biophysica acta. 1864(4 Pt A):1203-1215
Kundu, S., Bansal, S., Muthukumarasamy, K.M., Sachidanandan, C., Motiani, R.K., Bajaj, A. (2017) Deciphering the role of hydrophobic and hydrophilic bile acids in angiogenesis using in vitro and in vivo model systems.. MedChemComm. 8:2248-2257
Pandey, A., Ekka, M.K., Ranjan, S., Maitia, S., Sachidanandan, C. (2017) Teratogenic, cardiotoxic and hepatotoxic properties of related ionic liquids reveal the biological importance of anionic components. RSC Advances. 7 (37)
Mahale, S., Kumar, M., Sharma, A., Babu, A., Ranjan, S., Sachidanandan, C., Mylavarapu, S.V. (2016) The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Scientific Reports. 6:22
Asad, Z., Pandey, A., Babu, A., Sun, Y., Shevade, K., Kapoor, S., Ullah, I., Ranjan, S., Scaria, V., Bajpai, R., Sachidanandan, C. (2016) Rescue of neural crest derived phenotypes in a zebrafish CHARGE model by sox10 downregulation. Human molecular genetics. 25(16):3539-3554
Chetty, S.S., Praneetha, S., Basu, S., Sachidanandan, C., Murugan, A.V. (2016) Corrigendum: Sustainable, Rapid Synthesis of Bright-Luminescent CuInS2-ZnS Alloyed Nanocrystals: Multistage Nano-xenotoxicity Assessment and Intravital Fluorescence Bioimaging in Zebrafish-Embryos. Scientific Reports. 6:28607
Chetty, S.S., Praneetha, S., Basu, S., Sachidanandan, C., Murugan, A.V. (2016) Sustainable, Rapid Synthesis of Bright-Luminescent CuInS2-ZnS Alloyed Nanocrystals: Multistage Nano-xenotoxicity Assessment and Intravital Fluorescence Bioimaging in Zebrafish-Embryos. Scientific Reports. 6:26078
Singh, M., Bhartiya, D., Maini, J., Sharma, M., Singh, A.R., Kadarkaraisamy, S., Rana, R., Sabharwal, A., Nanda, S., Ramachandran, A., Mittal, A., Kapoor, S., Sehgal, P., Asad, Z., Kaushik, K., Vellarikkal, S.K., Jagga, D., Muthuswami, M., Chauhan, R.K., Leonard, E., Priyadarshini, R., Halimani, M., Malhotra, S., Patowary, A., Vishwakarma, H., Joshi, P., Bhardwaj, V., Bhaumik, A., Bhatt, B., Jha, A., Kumar, A., Budakoti, P., Lalwani, M.K., Meli, R., Jalali, S., Joshi, K., Pal, K., Dhiman, H., Laddha, S.V., Jadhav, V., Singh, N., Pandey, V., Sachidanandan, C., Ekker, S.C., Klee, E.W., Scaria, V., Sivasubbu, S. (2014) The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation. Database : the journal of biological databases and curation. 2014:bau011
Sivasubbu, S., Sachidanandan, C., and Scaria, V. (2013) Time for the zebrafish ENCODE. Journal of genetics. 92(3):695-701
Basu, S., and Sachidanandan, C. (2013) Zebrafish: A Multifaceted Tool for Chemical Biologists. Chemical Reviews. 113(10):7952-80
Becker, J.R., Robinson, T.Y., Sachidanandan, C., Kelly, A.E., Coy, S., Peterson, R.T., and MacRae, C.A. (2012) In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signaling. Cardiovascular research. 93(3):463-470
Steinbicker, A.U., Sachidanandan, C., Vonner, A.J., Yusuf, R.Z., Deng, D.Y., Lai, C.S., Rauwerdink, K.M., Winn, J.C., Saez, B., Cook, C.M., Szekely, B.A., Roy, C.N., Seehra, J.S., Cuny, G.D., Scadden, D.T., Peterson, R.T., Bloch, K.D., and Yu, P.B. (2011) Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood. 117(18):4915-23
Sachidanandan, C., Yeh, J.R., Peterson, Q.P., and Peterson, R.T. (2008) Identification of a novel retinoid by small molecule screening with zebrafish embryos. PLoS One. 3(4):e1947
Yu, P.B., Hong, C.C., Sachidanandan, C., Babitt, J.L., Deng, D.Y., Hoyng, S.A., Lin, H.Y., Bloch, K.D., and Peterson, R.T. (2008) Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nature Chemical Biology. 4(1):33-41

NON-ZEBRAFISH PUBLICATIONS
The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation.
Singh M, Bhartiya D, Maini J, Sharma M, Singh AR, Kadarkaraisamy S, Rana R, Sabharwal A, Nanda S, Ramachandran A, Mittal A, Kapoor S, Sehgal P, Asad Z, Kaushik K, Vellarikkal SK, Jagga D, Muthuswami M, Chauhan RK, Leonard E, Priyadarshini R, Halimani M, Malhotra S, Patowary A, Vishwakarma H, Joshi P, Bhardwaj V, Bhaumik A, Bhatt B, Jha A, Kumar A, Budakoti P, Lalwani MK, Meli R, Jalali S, Joshi K, Pal K, Dhiman H, Laddha SV, Jadhav V, Singh N, Pandey V, Sachidanandan C, Ekker SC, Klee EW, Scaria V, Sivasubbu S.
Database (Oxford). 2014 Feb 26;2014:bau011. doi: 10.1093/database/bau011.

lncRNome: a comprehensive knowledgebase of human long noncoding RNAs.
Bhartiya D, Pal K, Ghosh S, Kapoor S, Jalali S, Panwar B, Jain S, Sati S, Sengupta S, Sachidanandan C, Raghava GP, Sivasubbu S, Scaria V.
Database (Oxford). 2013 Jul 11;2013:bat034. doi: 10.1093/database/bat034.

Conceptual approaches for lncRNA drug discovery and future strategies.
Bhartiya D, Kapoor S, Jalali S, Sati S, Kaushik K, Sachidanandan C, Sivasubbu S, Scaria V.
Expert Opin Drug Discov. 2012 Jun;7(6):503-13. doi: 10.1517/17460441.2012.682055.
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.