We have established an emergent research group, but with solid experience, scientific background and contrastable research results. Our line of research is focused on the analysis of the molecular mechanisms that regulate opioid activity, which is involved in pain modulation and in tolerance and dependence. At present, we have broaden our field of research towards the rewards the rewards pathway, mainly related to the opioid and dopaminergic neurotransmitter systems. We are analysing the in vivo effects of drug of abuse, and we are currently collaborating in the design of novel agents targetting the reward pathway. Our research model is the zebrafish, most of our assays are conducted with embryos and the obtained results are easily extrapolated to other vertebrates. We make use of a wide range of biochemical and Molecular Biology techniques, but we also use pharmacological and Cell Biology techniques. This approach allow us to analyze different levels of biological information: the genome, epigenome, transcriptome, proteome and metabolome. In addition to developing a basic line of research, we also collaborate with other scientists from diverse fields of knowlegde,as Medicinal Chemistry, Marine Biology, or even with Medical Doctor in Public Health from University of Salamanca. This multidisciplinary approach enables us to perform translational research with future applications in different research areas. We also spend on our lecturing and management duties, as well as in the transfer of knowledge. Finally, we actively take part in many activities for the Dissemination of Science.