ZFIN Person: Parsons, Michael

ZFIN ID: ZDB-PERS-060130-1

ZFIN ID: ZDB-PERS-060130-1

Parsons, Michael

Email:	mparson1@uci.edu
URL:	https://sites.uci.edu/parsonslab/
Affiliation:	Parsons Lab
Address:	Department of Developmental and Cell Biology 4101 Natural Sciences II University of California, Irvine 92697
Country:
Phone:	949 824 8728
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Shin, M., Yin, H.M., Shih, Y.H., Nozaki, T., Portman, D., Toles, B., Kolb, A., Luk, K., Isogai, S., Ishida, K., Hanasaka, T., Parsons, M.J., Wolfe, S.A., Burns, C.E., Burns, C.G., Lawson, N.D. (2023) Generation and application of endogenously floxed alleles for cell-specific knockout in zebrafish. Developmental Cell. 58(22):2614-2626.e7

Tucker, T.R., Knitter, C.A., Khoury, D.M., Eshghi, S., Tran, S., Sharrock, A.V., Wiles, T.J., Ackerley, D.F., Mumm, J.S., Parsons, M.J. (2023) A new model of inducible chronic hyperglycemia. Disease models & mechanisms. 16(8):

Edelman, H.E., McClymont, S.A., Tucker, T.R., Pineda, S., Beer, R.L., McCallion, A.S., Parsons, M.J. (2021) SOX9 modulates cancer biomarker and cilia genes in pancreatic cancer. Human molecular genetics. 30(6):485-499

So, J., Kim, M., Lee, S.H., Ko, S., Lee, D.A., Park, H., Azuma, M., Parsons, M.J., Prober, D., Shin, D. (2020) Attenuating the EGFR-ERK-SOX9 axis promotes liver progenitor cell-mediated liver regeneration in zebrafish. Hepatology (Baltimore, Md.). 73(4):1494-1508

Zhang, D., Gates, K.P., Barske, L., Wang, G., Lancman, J.J., Zeng, X.I., Groff, M., Wang, K., Parsons, M.J., Crump, J.G., Dong, P.D.S. (2017) Endoderm Jagged induces liver and pancreas duct lineage in zebrafish. Nature communications. 8:769

Huang, W., Beer, R.L., Delaspre, F., Wang, G., Edelman, H.E., Park, H., Azuma, M., Parsons, M.J. (2016) Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation. Developmental Biology. 418(1):28-39

Johnson, K., Barragan, J., Bashiruddin, S., Smith, C.J., Tyrrell, C., Parsons, M.J., Doris, R., Kucenas, S., Downes, G.B., Velez, C.M., Schneider, C., Sakai, C., Pathak, N., Anderson, K., Stein, R., Devoto, S.H., Mumm, J.S., Barresi, M.J. (2016) Gfap-positive radial glial cells are an essential progenitor population for later-born neurons and glia in the zebrafish spinal cord. Glia. 64(7):1170-89

Delaspre, F., Beer, R.L., Rovira, M., Huang, W., Wang, G., Gee, S., Vitery, M.D., Wheelan, S.J., Parsons, M.J. (2015) Centroacinar cells are progenitors that contribute to endocrine pancreas regeneration. Diabetes. 64(10):3499-509

Fischer, A., Wolman, M., Granato, M., Parsons, M., McCallion, A.S., Proescher, J., English, E. (2015) Carbamate nerve agent prophylatics exhibit distinct toxicological effects in the zebrafish embryo model. Neurotoxicology and teratology. 50:1-10

Wang, Y.J., Park, J.T., Parsons, M.J., Leach, S.D. (2015) Fate mapping of ptf1a-expressing cells during pancreatic organogenesis and regeneration in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 244(6):724-35

Park, J.T., Johnson, N., Liu, S., Levesque, M., Wang, Y.J., Ho, H., Huso, D., Maitra, A., Parsons, M.J., Prescott, J.D., Leach, S.D. (2015) Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey. Oncogene. 34(21):2801-6

Huang, W., Wang, G., Delaspre, F., Vitery, M.D., Beer, R.L., Parsons, M.J. (2014) Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development. Developmental Biology. 394(1):83-93

Subedi, A., Macurak, M., Gee, S.T., Monge, E., Goll, M.G., Potter, C.J., Parsons, M.J., and Halpern, M.E. (2014) Adoption of the Q transcriptional regulatory system for zebrafish transgenesis. Methods (San Diego, Calif.). 66(3):433-40

Quillien, A., Moore, J.C., Shin, M., Siekmann, A.F., Smith, T., Pan, L., Moens, C.B., Parsons, M.J., Lawson, N.D. (2014) Distinct Notch signaling outputs pattern the developing arterial system. Development (Cambridge, England). 141:1544-52

Matsuda, H., Parsons, M.J., and Leach, S.D. (2013) Aldh1-expressing endocrine progenitor cells regulate secondary islet formation in larval zebrafish pancreas. PLoS One. 8(9):e74350

Provost, E., Wehner, K.A., Zhong, X., Ashar, F., Nguyen, E., Green, R., Parsons, M.J., and Leach, S.D. (2012) Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development. Development (Cambridge, England). 139(17):3232-3241

Manfroid, I., Ghaye, A., Naye, F., Detry, N., Palm, S., Pan, L., Ma, T.P., Huang, W., Rovira, M., Martial, J.A., Parsons, M.J., Moens, C.B., Voz, M.L., and Peers, B. (2012) Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Developmental Biology. 366(2):268-278

Walker, S.L., Ariga, J., Mathias, J.R., Coothankandaswamy, V., Xie, X., Distel, M., Köster, R.W., Parsons, M.J., Bhalla, K.N., Saxena, M.T., and Mumm, J.S. (2012) Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish. PLoS One. 7(1):e29916

Kague, E., Gallagher, M., Burke, S., Parsons, M., Franz-Odendaal, T., and Fisher, S. (2012) Skeletogenic fate of zebrafish cranial and trunk neural crest. PLoS One. 7(11):e47394

Rovira, M., Huang, W., Yusuff, S., Shim, J.S., Ferrante, A.A., Liu, J.O., and Parsons, M.J. (2011) Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation. Proceedings of the National Academy of Sciences of the United States of America. 108(48):19264-9

Wang, Y., Rovira, M., Yusuff, S., and Parsons, M.J. (2011) Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing {beta}-cells. Development (Cambridge, England). 138(4):609-617

Parsons, K.J., Andreeva, V., James Cooper, W., Yelick, P.C., and Craig Albertson, R. (2011) Morphogenesis of the zebrafish jaw: development beyond the embryo. Methods in cell biology. 101:225-248

Williams, P.R., Suzuki, S.C., Yoshimatsu, T., Lawrence, O.T., Waldron, S.J., Parsons, M.J., Nonet, M.L., and Wong, R.O. (2010) In vivo development of outer retinal synapses in the absence of glial contact. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(36):11951-11961

Kani, S., Bae, Y.K., Shimizu, T., Tanabe, K., Satou, C., Parsons, M.J., Scott, E., Higashijima, S.I., and Hibi, M. (2010) Proneural gene-linked neurogenesis in zebrafish cerebellum. Developmental Biology. 343(1-2):1-17

Montgomery, J.E., Parsons, M.J., and Hyde, D.R. (2010) A novel model of retinal ablation demonstrates that the extent of rod cell death regulates the origin of the regenerated zebrafish rod photoreceptors. The Journal of comparative neurology. 518(6):800-814

Parsons, M.J., Pisharath, H., Yusuff, S., Moore, J.C., Siekmann, A.F., Lawson, N., and Leach, S.D. (2009) Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mechanisms of Development. 126(10):898-912

Moss, J.B., Koustubhan, P., Greenman, M., Parsons, M.J., Walter, I., and Moss, L.G. (2009) Regeneration of the Pancreas in Adult Zebrafish. Diabetes. 58(8):1844-1851

Pisharath, H., and Parsons, M.J. (2009) Nitroreductase-mediated cell ablation in transgenic zebrafish embryos. Methods in molecular biology (Clifton, N.J.). 546:133-143

Halpern, M.E., Rhee, J., Goll, M.G., Akitake, C.M., Parsons, M., and Leach, S.D. (2008) Gal4/UAS transgenic tools and their application to zebrafish. Zebrafish. 5(2):97-110

Davison, J.M., Akitake, C.M., Goll, M.G., Rhee, J.M., Gosse, N., Baier, H., Halpern, M.E., Leach, S.D., and Parsons, M.J. (2007) Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish. Developmental Biology. 304(2):811-824

Pisharath, H., Rhee, J.M., Swanson, M.A., Leach, S.D., and Parsons, M.J. (2007) Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase. Mechanisms of Development. 124(3):218-229

Pollard, S.M., Parsons, M.J., Kamei, M., Kettleborough, R.N., Thomas, K.A., Pham, V.N., Bae, M.K., Scott, A., Weinstein, B.M., and Stemple, D.L. (2006) Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation. Developmental Biology. 289(1):64-76

Coutinho, P., Parsons, M.J., Thomas, K.A., Hirst, E.M., Saude, L., Campos, I., Williams, P.H., Stemple, D.L. (2004) Differential Requirements for COPI Transport during Vertebrate Early Development. Developmental Cell. 7(4):547-558

Feldman, B., Concha, M.L., Saude, L., Parsons, M.J., Adams, R.J., Wilson, S.W., and Stemple, D.L. (2002) Lefty antagonism of squint is essential for normal gastrulation. Current biology : CB. 12(24):2129-2135

Parsons, M.J., Pollard, S.M., Saude, L., Feldman, B., Coutinho, P., Hirst, E.M., and Stemple, D.L. (2002) Zebrafish mutants identify an essential role for laminins in notochord formation. Development (Cambridge, England). 129(13):3137-3146

Parsons, M.J., Campos, I., Hirst, E.M.A., and Stemple, D.L. (2002) Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos. Development (Cambridge, England). 129(14):3505-3512

NON-ZEBRAFISH PUBLICATIONS