ZFIN ID: ZDB-PERS-050712-3
Zetterberg, Henrik
Email: henrik.zetterberg@clinchem.gu.se
URL: http://www.neurophys.gu.se
Affiliation:
Address: Institute of Neuroscience and Physiology Department of Psychiatry and Neurochemistry The Sahlgrenska Academy at University of Gothenburg Sahlgrenska University Hospital/Molndal V-huset Molndal, SE-431 80 Sweden
Country:
Phone: +46 31 3430025
Fax: +46 31 3432426
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS
Henrik Zetterberg is a Professor of Neurochemistry and has a research background in molecular biology and clinical chemistry. He has spent the past 10 years focusing on the development of biomarkers for Alzheimer disease and other brain disorders, including traumatic brain injury. His research is translational and involves evaluation of biomarkers in cell and animal models, including zebrafish, as well as in longitudinal studies of patients and healthy individuals. H. Zetterberg is a specialist in clinical chemistry and Head of the Department of Psychiatry and Neurochemistry at the Sahlgrenska Academy, University of Gothenburg, Sweden. He is also a Guest Professor at the Institute of Neurology, University College London, UK. He has published more than 300 scientific articles and has received the Erik K. Fernström prize for young scientists and the Inga Sandeborg prize for research on Alzheimer disease.


PUBLICATIONS
Larsson, P., Pettersson, D., Olsson, M., Sarathchandra, S., Abramsson, A., Zetterberg, H., Ittner, E., Forssell-Aronsson, E., Kovács, A., Karlsson, P., Helou, K., Parris, T.Z. (2024) Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer. Cell death discovery. 10:5757
Chebli, J., Rahmati, M., Lashley, T., Edeman, B., Oldfors, A., Zetterberg, H., Abramsson, A. (2021) The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish. Scientific Reports. 11:19115
Banote, R.K., Chebli, J., Şatır, T.M., Varshney, G.K., Camacho, R., Ledin, J., Burgess, S.M., Abramsson, A., Zetterberg, H. (2020) Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish. Scientific Reports. 10:10127
Mushtaq, M., Kovalevska, L., Darekar, S., Abramsson, A., Zetterberg, H., Kashuba, V., Klein, G., Arsenian-Henriksson, M., Kashuba, E. (2020) Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2. Proceedings of the National Academy of Sciences of the United States of America. 117(27):15673-15683
Hedberg-Oldfors, C., Abramsson, A., Osborn, D.P.S., Danielsson, O., Fazlinezhad, A., Nilipour, Y., Hübbert, L., Nennesmo, I., Visuttijai, K., Bharj, J., Petropoulou, E., Shoreim, A., Vona, B., Ahangari, N., López, M.D., Doosti, M., Banote, R.K., Maroofian, R., Edling, M., Taherpour, M., Zetterberg Md, H., Karimiani, E.G., Oldfors, A., Jamshidi, Y. (2019) Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24. Human molecular genetics. 28(11):1919-1929
Banote, R.K., Edling, M., Eliassen, F., Kettunen, P., Zetterberg, H., Abramsson, A. (2016) β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner. Developmental Biology. 413(1):26-38
Abramsson, A., Kettunen, P., Banote, R.K., Lott, E., Li, M., Arner, A., and Zetterberg, H. (2013) The zebrafish amyloid precursor protein-b is required for motor neuron guidance and synapse formation. Developmental Biology. 381(2):377-88
Andersson Lendahl, M., and Zetterberg, H. (2013) The Nordic countries meeting on the zebrafish as a model for development and disease 2012. Zebrafish. 10(1):124-125
Westman-Brinkmalm, A., Abramsson, A., Pannee, J., Gang, C., Gustavsson, M.K., von Otter, M., Blennow, K., Brinkmalm, G., Heumann, H., and Zetterberg, H. (2011) SILAC zebrafish for quantitative analysis of protein turnover and tissue regeneration. Journal of proteomics. 75(2):425-34
Zetterberg, H. (2011) Zebrafish physiology: big interest in a small fish. Acta physiologica (Oxford, England). 201(3):295-296
Abramsson, A., Westman-Brinkmalm, A., Pannee, J., Gustavsson, M., von Otter, M., Blennow, K., Brinkmalm, G., Kettunen, P., and Zetterberg, H. (2010) Proteomics Profiling of Single Organs from Individual Adult Zebrafish. Zebrafish. 7(2):161-168
Zetterberg, H., Campbell, W.A., Yang, H.W., and Xia, W. (2006) The Cytosolic Loop of the γ-Secretase Component Presenilin Enhancer 2 Protects Zebrafish Embryos from Apoptosis. The Journal of biological chemistry. 281(17):11933-11939
Campbell, W.A., Yang, H., Zetterberg, H., Baulac, S., Sears, J.A., Liu, T., Wong, S.T., Zhong, T.P., and Xia, W. (2006) Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss. Journal of neurochemistry. 96(5):1423-1440

NON-ZEBRAFISH PUBLICATIONS
330 publications in PubMed
5600 citations according to Web of Knowledge, h-index 34 at age 39 years, January 2013