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ZFIN ID:
ZDB-PERS-050510-2
Hassel, David
Email:
david.hassel@med.uni-heidelberg.de
URL:
Affiliation:
Hassel Lab
Address:
University of Heidelberg Department of Internal Medicine III- Cardiology Im Neuenheimer Feld 350 Heidelberg, 69120 Germany
Country:
Germany
Phone:
Fax:
ORCID ID:
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Hoffmann, S., Roeth, R., Diebold, S., Gogel, J., Hassel, D., Just, S., Rappold, G.A. (2021) Identification and Tissue-Specific Characterization of Novel SHOX-Regulated Genes in Zebrafish Highlights SOX Family Members Among Other Genes. Frontiers in genetics. 12:688808
Dicks, S., Jürgensen, L., Leuschner, F., Hassel, D., Andrieux, G., Boerries, M. (2020) Cardiac Regeneration and Tumor Growth-What Do They Have in Common?. Frontiers in genetics. 11:586658
Heigwer, J., Kutzner, J., Haeussler, M., Burkhalter, M.D., Draebing, T., Juergensen, L., Katus, H.A., Philipp, M., Westhoff, J.H., Hassel, D. (2020) miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis. Biochemical and Biophysical Research Communications. 527(2):432-439
Hoelscher, S.C., Stich, T., Diehm, A., Lahm, H., Dreßen, M., Zhang, Z., Neb, I., Aherrahrou, Z., Erdmann, J., Schunkert, H., Santamaria, G., Cuda, G., Gilsbach, R., Hein, L., Lange, R., Hassel, D., Krane, M., Doppler, S.A. (2020) miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations. International Journal of Molecular Sciences. 21(3):
Hein, S., Hassel, D., Kararigas, G. (2019) The Zebrafish (
Danio rerio
) Is a Relevant Model for Studying Sex-Specific Effects of 17β-Estradiol in the Adult Heart. International Journal of Molecular Sciences. 20(24):
Verhagen, J.M.A., van den Born, M., van der Linde, H.C., Nikkels, P.G.J., Verdijk, R.M., Kivlen, M.H., van Unen, L.M.A., Baas, A.F., Ter Heide, H., van Osch-Gevers, L., Hoogeveen-Westerveld, M., Herkert, J.C., Bertoli-Avella, A.M., van Slegtenhorst, M.A., Wessels, M.W., Verheijen, F.W., Hassel, D., Hofstra, R.M.W., Hegde, R.S., van Hasselt, P.M., van Ham, T.J., van de Laar, I.M.B.H. (2019) Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of Tail-anchored Proteins, Cause Rapidly Progressive Pediatric Cardiomyopathy. Circulation. Genomic and precision medicine. 12(9):397-406
Klett, H., Jürgensen, L., Most, P., Busch, M., Günther, F., Dobreva, G., Leuschner, F., Hassel, D., Busch, H., Boerries, M. (2018) Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration. Biomolecules. 9(1)
Fleming, N.D., Samsa, L.A., Hassel, D., Qian, L., Liu, J. (2018) Rapamycin attenuates pathological hypertrophy caused by an absence of trabecular formation. Scientific Reports. 8:8584
Montalbano, A., Juergensen, L., Fukami, M., Thiel, C.T., Hauer, N.H., Roeth, R., Weiss, B., Naiki, Y., Ogata, T., Hassel, D., Rappold, G.A. (2018) Functional missense and splicing variants in the retinoic acid catabolizing enzyme CYP26C1 in idiopathic short stature. European journal of human genetics : EJHG. 26(8):1113-1120
Kossack, M., Hein, S., Juergensen, L., Siragusa, M., Benz, A., Katus, H.A., Most, P., Hassel, D. (2017) Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. Journal of Molecular and Cellular Cardiology. 108:95-105
Montalbano, A., Juergensen, L., Roeth, R., Weiss, B., Fukami, M., Fricke-Otto, S., Binder, G., Ogata, T., Decker, E., Nuernberg, G., Hassel, D., Rappold, G.A. (2016) Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency. EMBO Molecular Medicine. 8(12):1455-1469
Benz, A., Kossack, M., Auth, D., Seyler, C., Zitron, E., Juergensen, L., Katus, H.A., Hassel, D. (2016) miR-19b Regulates Ventricular Action Potential Duration in Zebrafish. Scientific Reports. 6:36033
Scheid, L.M., Mosqueira, M., Hein, S., Kossack, M., Juergensen, L., Mueller, M., Meder, B., Fink, R.H., Katus, H.A., Hassel, D. (2016) Essential light chain S195 phosphorylation is required for cardiac adaptation under physical stress. Cardiovascular research. 111(1):44-55
Hein, S.J., Lehmann, L.H., Kossack, M., Juergensen, L., Fuchs, D., Katus, H.A., Hassel, D. (2015) Advanced Echocardiography in Adult Zebrafish Reveals Delayed Recovery of Heart Function after Myocardial Cryoinjury. PLoS One. 10:e0122665
Renz, M., Otten, C., Faurobert, E., Rudolph, F., Zhu, Y., Boulday, G., Duchene, J., Mickoleit, M., Dietrich, A.C., Ramspacher, C., Steed, E., Manet-Dupé, S., Benz, A., Hassel, D., Vermot, J., Huisken, J., Tournier-Lasserve, E., Felbor, U., Sure, U., Albiges-Rizo, C., Abdelilah-Seyfried, S. (2015) Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins. Developmental Cell. 32:181-190
Cheng, P., Andersen, P., Hassel, D., Kaynak, B.L., Limphong, P., Juergensen, L., Kwon, C., and Srivastava, D. (2013) Fibronectin mediates mesendodermal cell fate decisions. Development (Cambridge, England). 140(12):2587-2596
Hassel, D., Cheng, P., White, M.P., Ivey, K.N., Kroll, J., Augustin, H.G., Katus, H.A., Stainier, D.Y., and Srivastava, D. (2012) MicroRNA-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting Vascular Endothelial Growth Factor Signaling. Circulation research. 111(11):1421-1433
Völkers, M., Dolatabadi, N., Gude, N., Most, P., Sussman, M.A., and Hassel, D. (2012) Orai1 deficiency leads to heart failure and skeletal myopathy in zebrafish. Journal of Cell Science. 125(2):287-294
Gierten, J., Hassel, D., Schweizer, P.A., Becker, R., Katus, H.A., and Thomas, D. (2012) Identification and functional characterization of zebrafish K
2P
10.1 (TREK2) two-pore-domain K
+
channels. Biomembranes. 1818(1):33-41
Just, S., Meder, B., Berger, I.M., Etard, C., Trano, N., Patzel, E., Hassel, D., Marquart, S., Dahme, T., Vogel, B., Fishman, M.C., Katus, H.A., Strähle, U., and Rottbauer, W. (2011) The myosin-interacting protein SMYD1 is essential for sarcomere organization. Journal of Cell Science. 124(Pt 18):3127-36
Meder, B., Scholz, E.P., Hassel, D., Wolff, C., Just, S., Berger, I.M., Patzel, E., Karle, C., Katus, H.A., and Rottbauer, W. (2011) Reconstitution of defective protein trafficking rescues Long-QT syndrome in zebrafish. Biochemical and Biophysical Research Communications. 408(2):218-224
Liu, J., Bressan, M., Hassel, D., Huisken, J., Staudt, D., Kikuchi, K., Poss, K.D., Mikawa, T., and Stainier, D.Y. (2010) A dual role for ErbB2 signaling in cardiac trabeculation. Development (Cambridge, England). 137(22):3867-3875
Hassel, D., Dahme, T., Erdmann, J., Meder, B., Huge, A., Stoll, M., Just, S., Hess, A., Ehlermann, P., Weichenhan, D., Grimmler, M., Liptau, H., Hetzer, R., Regitz-Zagrosek, V., Fischer, C., Nürnberg, P., Schunkert, H., Katus, H.A., and Rottbauer, W. (2009) Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. Nature medicine. 15(11):1281-1288
Scholz, E.P., Niemer, N., Hassel, D., Zitron, E., Bürgers, H.F., Bloehs, R., Seyler, C., Scherer, D., Thomas, D., Kathöfer, S., Katus, H.A., Rottbauer, W.A., and Karle, C.A. (2009) Biophysical properties of zebrafish ether-à-go-go related gene potassium channels. Biochemical and Biophysical Research Communications. 381(2):159-164
Meder, B., Laufer, C., Hassel, D., Just, S., Marquart, S., Vogel, B., Hess, A., Fishman, M.C., Katus, H.A., and Rottbauer, W. (2009) A Single Serine in the Carboxyl Terminus of Cardiac Essential Myosin Light Chain-1 Controls Cardiomyocyte Contractility In Vivo. Circulation research. 104(5):650-659
Hassel, D., Scholz, E.P., Trano, N., Friedrich, O., Just, S., Meder, B., Weiss, D.L., Zitron, E., Marquart, S., Vogel, B., Karle, C.A., Seemann, G., Fishman, M.C., Katus, H.A., and Rottbauer, W. (2008) Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants. Circulation. 117(7):866-875
Rottbauer, W., Wessels, G., Dahme, T., Just, S., Trano, N., Hassel, D., Burns, C.G., Katus, H.A., and Fishman, M.C. (2006) Cardiac Myosin Light Chain-2. A Novel Essential Component of Thick-Myofilament Assembly and Contractility of the Heart. Circulation research. 99(3):323-331
NON-ZEBRAFISH PUBLICATIONS
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