ZFIN ID: ZDB-PERS-050502-29
Epting, Daniel
Email: daniel.epting@uniklinik-freiburg.de
Affiliation: Kramer-Zucker Lab
Address: Bergmann Lab Renal Division, Walz Laboratories University Hospital Freiburg Hugstetter Strasse 55 Freiburg, 79106 Germany
Country: Germany
Phone: +49 (0) 761 270 3383
Fax: +49 (0) 761 5108 744


Epting, D., Senaratne, L.D.S., Ott, E., Holmgren, A., Sumathipala, D., Larsen, S.M., Wallmeier, J., Bracht, D., Frikstad, K.M., Crowley, S., Sikiric, A., Barøy, T., Käsmann-Kellner, B., Decker, E., Decker, C., Bachmann, N., Patzke, S., Phelps, I.G., Katsanis, N., Giles, R., Schmidts, M., Zucknick, M., Lienkamp, S.S., Omran, H., Davis, E.E., Doherty, D., Strømme, P., Frengen, E., Bergmann, C., Misceo, D. (2020) Loss of CBY1 results in a ciliopathy characterized by features of Joubert syndrome. Human Mutation. 41(12):2179-2194
Hoff, S., Epting, D., Falk, N., Schroda, S., Braun, D.A., Halbritter, J., Hildebrandt, F., Kramer-Zucker, A., Bergmann, C., Walz, G., Lienkamp, S.S. (2018) The nucleoside diphosphate kinase NME3 associates with nephronophthisis proteins, and is required for ciliary function during renal development. The Journal of biological chemistry. 293(39):15243-15255
Lu, H., Galeano, M.C.R., Ott, E., Kaeslin, G., Kausalya, P.J., Kramer, C., Ortiz-Brüchle, N., Hilger, N., Metzis, V., Hiersche, M., Tay, S.Y., Tunningley, R., Vij, S., Courtney, A.D., Whittle, B., Wühl, E., Vester, U., Hartleben, B., Neuber, S., Frank, V., Little, M.H., Epting, D., Papathanasiou, P., Perkins, A.C., Wright, G.D., Hunziker, W., Gee, H.Y., Otto, E.A., Zerres, K., Hildebrandt, F., Roy, S., Wicking, C., Bergmann, C. (2017) Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease. Nature Genetics. 49:1025–1034
Esser, J.S., Charlet, A., Schmidt, M., Heck, S., Allen, A., Lother, A., Epting, D., Patterson, C., Bode, C., Moser, M. (2017) The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Cardiovascular research. 113(2):222-223
Wuttke, M., Wong, C.S., Wühl, E., Epting, D., Luo, L., Hoppmann, A., Doyon, A., Li, Y., Sözeri, B., Thurn, D., Helmstädter, M., Huber, T.B., Blydt-Hansen, T.D., Kramer-Zucker, A., Mehls, O., Melk, A., Querfeld, U., Furth, S.L., Warady, B.A., Schaefer, F., Köttgen, A. (2016) Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium.. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 31(2):262-269
Epting, D., Slanchev, K., Boehlke, C., Hoff, S., Loges, N.T., Yasunaga, T., Indorf, L., Nestel, S., Lienkamp, S.S., Omran, H., Kuehn, E.W., Ronneberger, O., Walz, G., Kramer-Zucker, A. (2015) The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin. Development (Cambridge, England). 142:174-84
Kim, Y.H., Epting, D., Slanchev, K., Engel, C., Walz, G., and Kramer-Zucker, A. (2013) A Complex of BBS1 and NPHP7 Is Required for Cilia Motility in Zebrafish. PLoS One. 8(9):e72549
Hoff, S., Halbritter, J., Epting, D., Frank, V., Nguyen, T.M., van Reeuwijk, J., Boehlke, C., Schell, C., Yasunaga, T., Helmstädter, M., Mergen, M., Filhol, E., Boldt, K., Horn, N., Ueffing, M., Otto, E.A., Eisenberger, T., Elting, M.W., van Wijk, J.A., Bockenhauer, D., Sebire, N.J., Rittig, S., Vyberg, M., Ring, T., Pohl, M., Pape, L., Neuhaus, T.J., Elshakhs, N.A., Koon, S.J., Harris, P.C., Grahammer, F., Huber, T.B., Kuehn, E.W., Kramer-Zucker, A., Bolz, H.J., Roepman, R., Saunier, S., Walz, G., Hildebrandt, F., Bergmann, C., and Lienkamp, S.S. (2013) ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nature Genetics. 45(8):951-6
Epting, D., Wendik, B., Bennewitz, K., Dietz, C.T., Driever, W., and Kroll, J. (2010) The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish. Circulation research. 107(1):45-55
Epting, D., Vorwerk, S., Hageman, A., and Meyer, D. (2007) Expression of rasgef1b in zebrafish. Gene expression patterns : GEP. 7(4):389-395

Epting, D. (2009) Analysis of G-protein signaling molecules during vertebrate development and angiogenesis. University Dissertation, Freiburg.

Jens Kroll*, Daniel Epting*, Katrin Kern, Christian T. Dietz, Yuxi Feng, Hans-Peter Hammes, Thomas Wieland and Hellmut G. Augustin (2009)
Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis
Am J Physiol Heart Circ Physiol 296:893-899, 2009.
* equal contribution