ZFIN ID: ZDB-PERS-050502-10
Prober, David
Email: dprober@caltech.edu
URL: http://biology.caltech.edu/Members/Prober
Affiliation: Prober Lab
Address: California Institute of Technology Division of Biology 1200 E. California Blvd Pasadena, CA 91125 USA
Country: United States


Barlow, I.L., Mackay, E., Wheater, E., Goel, A., Lim, S., Zimmerman, S., Woods, I., Prober, D.A., Rihel, J. (2023) The zebrafish mutant dreammist implicates sodium homeostasis in sleep regulation. eLIFE. 12:
Pollak, D.J., Chawla, G., Andreev, A., Prober, D.A. (2023) First steps into the cloud: Using Amazon data storage and computing with Python notebooks. PLoS One. 18:e0278316e0278316
Wagle, M., Zarei, M., Lovett-Barron, M., Poston, K.T., Xu, J., Ramey, V., Pollard, K.S., Prober, D.A., Schulkin, J., Deisseroth, K., Guo, S. (2022) Brain-wide perception of the emotional valence of light is regulated by distinct hypothalamic neurons. Molecular psychiatry. 27(9):3777-3793
Lee, D.A., Oikonomou, G., Cammidge, T., Andreev, A., Hong, Y., Hurley, H., Prober, D.A. (2020) Neuropeptide VF neurons promote sleep via the serotonergic raphe. eLIFE. 9:
So, J., Kim, M., Lee, S.H., Ko, S., Lee, D.A., Park, H., Azuma, M., Parsons, M.J., Prober, D., Shin, D. (2020) Attenuating the EGFR-ERK-SOX9 axis promotes liver progenitor cell-mediated liver regeneration in zebrafish. Hepatology (Baltimore, Md.). 73(4):1494-1508
Bassi, I., Luzzani, F., Marelli, F., Vezzoli, V., Cotellessa, L., Prober, D.A., Persani, L., Gothilf, Y., Bonomi, M. (2020) Knocking-down of the Prokineticin receptor 2 affects reveals its complex role in the regulation of the hypothalamus-pituitary-gonadal axis in the zebrafish model. Scientific Reports. 10:7632
Ly, S., Lee, D.A., Strus, E., Prober, D.A., Naidoo, N. (2020) Evolutionarily Conserved Regulation of Sleep by the Protein Translational Regulator PERK. Current biology : CB. 30(9):1639-1648.e3
Lee, D.A., Liu, J., Hong, Y., Lane, J.M., Hill, A.J., Hou, S.L., Wang, H., Oikonomou, G., Pham, U., Engle, J., Saxena, R., Prober, D.A. (2019) Evolutionarily conserved regulation of sleep by epidermal growth factor receptor signaling. Science advances. 5:eaax4249
Mosser, E.A., Chiu, C.N., Tamai, T.K., Hirota, T., Li, S., Hui, M., Wang, A., Singh, C., Giovanni, A., Kay, S.A., Prober, D.A. (2019) Identification of pathways that regulate circadian rhythms using a larval zebrafish small molecule screen. Scientific Reports. 9:12405
Ruzzo, E.K., Pérez-Cano, L., Jung, J.Y., Wang, L.K., Kashef-Haghighi, D., Hartl, C., Singh, C., Xu, J., Hoekstra, J.N., Leventhal, O., Leppä, V.M., Gandal, M.J., Paskov, K., Stockham, N., Polioudakis, D., Lowe, J.K., Prober, D.A., Geschwind, D.H., Wall, D.P. (2019) Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks. Cell. 178:850-866.e26
Oikonomou, G., Altermatt, M., Zhang, R.W., Coughlin, G.M., Montz, C., Gradinaru, V., Prober, D.A. (2019) The Serotonergic Raphe Promote Sleep in Zebrafish and Mice. Neuron. 103(4):686-701.e8
Zhang, R.W., Du, W.J., Prober, D.A., Du, J.L. (2019) Müller Glial Cells Participate in Retinal Waves via Glutamate Transporters and AMPA Receptors. Cell Reports. 27:2871-2880.e2
Fontenas, L., Welsh, T.G., Piller, M., Coughenour, P., Gandhi, A.V., Prober, D.A., Kucenas, S. (2019) The Neuromodulator Adenosine Regulates Oligodendrocyte Migration at Motor Exit Point Transition Zones. Cell Reports. 27:115-128.e5
Singh, C., Rihel, J., Prober, D.A. (2017) Neuropeptide Y Regulates Sleep by Modulating Noradrenergic Signaling. Current biology : CB. 27(24):3796-3811.e5
Lee, D.A., Andreev, A., Truong, T.V., Chen, A., Hill, A.J., Oikonomou, G., Pham, U., Hong, Y.K., Tran, S., Glass, L., Sapin, V., Engle, J., Fraser, S.E., Prober, D.A. (2017) Genetic and neuronal regulation of sleep by neuropeptide VF. eLIFE. 6
Schoppik, D., Bianco, I.H., Prober, D.A., Douglass, A.D., Robson, D.N., Li, J.M.B., Greenwood, J.S.F., Soucy, E., Engert, F., Schier, A.F. (2017) Gaze-stabilizing central vestibular neurons project asymmetrically to extraocular motoneuron pools. The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(47):11353-11365
Chen, S., Reichert, S., Singh, C., Oikonomou, G., Rihel, J., Prober, D.A. (2017) Light-Dependent Regulation of Sleep and Wake States by Prokineticin 2 in Zebrafish. Neuron. 95(1):153-168.e6
Oikonomou, G., Prober, D.A. (2017) Attacking sleep from a new angle: contributions from zebrafish. Current opinion in neurobiology. 44:80-88
Chen, A., Singh, C., Oikonomou, G., Prober, D.A. (2017) Genetic Analysis of Histamine Signaling in Larval Zebrafish Sleep. eNeuro. 4(1)
Suarez-Bregua, P., Torres-Nuñez, E., Saxena, A., Guerreiro, P., Braasch, I., Prober, D.A., Moran, P., Cerda-Reverter, J.M., Du, S.J., Adrio, F., Power, D.M., Canario, A.V., Postlethwait, J.H., Bronner, M.E., Cañestro, C., Rotllant, J. (2017) Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31:569-583
Zhao, Y., Singh, C., Prober, D., Wayne, N.L. (2016) Morphological and Physiological Interactions between GnRH3 and Hypocretin/Orexin Neuronal Systems in Zebrafish (Danio rerio). Endocrinology. 157(10):4012-4020
Choi, H.M., Calvert, C.R., Husain, N., Huss, D., Barsi, J.C., Deverman, B.E., Hunter, R.C., Kato, M., Lee, S.M., Abelin, A.C., Rosenthal, A.Z., Akbari, O.S., Li, Y., Hay, B.A., Sternberg, P.W., Patterson, P.H., Davidson, E.H., Mazmanian, S.K., Prober, D.A., van de Rijn, M., Leadbetter, J.R., Newman, D.K., Readhead, C., Bronner, M.E., Wold, B., Lansford, R., Sauka-Spengler, T., Fraser, S.E., Pierce, N.A. (2016) Mapping a multiplexed zoo of mRNA expression. Development (Cambridge, England). 143:3632-3637
Prober, David (2016) Erratum: Chen et al., QRFP and Its Receptors Regulate Locomotor Activity and Sleep in Zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36:5429-5430
Chiu, C.N., Rihel, J., Lee, D.A., Singh, C., Mosser, E.A., Chen, S., Sapin, V., Pham, U., Engle, J., Niles, B.J., Montz, C.J., Chakravarthy, S., Zimmerman, S., Salehi-Ashtiani, K., Vidal, M., Schier, A.F., Prober, D.A. (2016) A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron. 89:842-856
Chen, A., Chiu, C.N., Mosser, E.A., Kahn, S., Spence, R., Prober, D.A. (2016) QRFP and Its Receptors Regulate Locomotor Activity and Sleep in Zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(6):1823-40
Chen, S., Chiu, C.N., McArthur, K.L., Fetcho, J.R., Prober, D.A. (2016) TRP channel mediated neuronal activation and ablation in freely behaving zebrafish. Nature Methods. 13(2):147-50
Singh, C., Oikonomou, G., Prober, D.A. (2015) Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish. eLIFE. 4:e07000
Gandhi, A.V., Mosser, E.A., Oikonomou, G., Prober, D.A. (2015) Melatonin Is Required for the Circadian Regulation of Sleep. Neuron. 85(6):1193-9
Liu, J., Merkle, F.T., Gandhi, A.V., Gagnon, J.A., Woods, I.G., Chiu, C.N., Shimogori, T., Schier, A.F., Prober, D.A. (2015) Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development (Cambridge, England). 142(6):1113-24
Chiu, C.N., and Prober, D.A. (2013) Regulation of zebrafish sleep and arousal states: current and prospective approaches. Frontiers in neural circuits. 7:58
Chen, S., Oikonomou, G., Chiu, C.N., Niles, B.J., Liu, J., Lee, D.A., Antoshechkin, I., and Prober, D.A. (2013) A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly. Nucleic acids research. 41(4):2769-2778
Pan, Y.A., Choy, M., Prober, D.A., and Schier, A.F. (2012) Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development (Cambridge, England). 139(3):591-600
Naumann, E.A., Kampff, A.R., Prober, D.A., Schier, A.F., and Engert, F. (2010) Monitoring neural activity with bioluminescence during natural behavior. Nature Neuroscience. 13(4):513-520
Rihel, J., Prober, D.A., Arvanites, A., Lam, K., Zimmerman, S., Jang, S., Haggarty, S.J., Kokel, D., Rubin, L.L., Peterson, R.T., and Schier, A.F. (2010) Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science (New York, N.Y.). 327(5963):348-351
Rihel, J., Prober, D.A., and Schier, A.F. (2010) Chapter 11 - Monitoring sleep and arousal in zebrafish. Methods in cell biology. 100:281-294
Caron, S.J., Prober, D., Choy, M., and Schier, A.F. (2008) In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development (Cambridge, England). 135(19):3259-3269
Prober, D.A., Zimmerman, S., Myers, B.R., McDermott, B.M. Jr, Kim, S.H., Caron, S., Rihel, J., Solnica-Krezel, L., Julius, D., Hudspeth, A.J., and Schier, A.F. (2008) Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(40):10102-10110
Prober, D.A., Rihel, J., Onah, A.A., Sung, R.J., and Schier, A.F. (2006) Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(51):13400-13410