ZFIN Person: Wagle, Mahendra

ZFIN ID: ZDB-PERS-050426-5

ZFIN ID: ZDB-PERS-050426-5

Wagle, Mahendra

Email:	mahendra_wagle@hotmail.com
URL:	https://profiles.ucsf.edu/mahendra.wagle
Affiliation:	Guo Lab
Address:	Department of Biopharmaceutical Sciences Programs in Biological Sciences, Human Genetics, Pharmaceutical Sciences and Pharmacogenomics Wheeler Center for the Neurobiology of Addiction University of California San Francisco Mission Bay Rock Hall 1550 4th Street San Francisco, CA 94143-2811 USA
Country:	United States
Phone:
Fax:
ORCID ID:	0000-0003-1802-9330

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Wagle, M., Zarei, M., Lovett-Barron, M., Poston, K.T., Xu, J., Ramey, V., Pollard, K.S., Prober, D.A., Schulkin, J., Deisseroth, K., Guo, S. (2022) Brain-wide perception of the emotional valence of light is regulated by distinct hypothalamic neurons. Molecular psychiatry. 27(9):3777-3793

Dahlén, A., Zarei, M., Melgoza, A., Wagle, M., Guo, S. (2021) THC-induced behavioral stereotypy in zebrafish as a model of psychosis-like behavior. Scientific Reports. 11:15693

Lovett-Barron, M., Chen, R., Bradbury, S., Andalman, A.S., Wagle, M., Guo, S., Deisseroth, K. (2020) Multiple convergent hypothalamus-brainstem circuits drive defensive behavior. Nature Neuroscience. 23(8):959-967

Dahlén, A., Wagle, M., Zarei, M., Guo, S. (2019) Heritable natural variation of light/dark preference in an outbred zebrafish population. Journal of neurogenetics. 33(4):199-208

Huang, R., Chen, M., Yang, L., Wagle, M., Guo, S., Hu, B. (2017) MicroRNA-133b Negatively Regulates Zebrafish Single Mauthner-Cell Axon Regeneration through Targeting tppp3 in Vivo.. Frontiers in molecular neuroscience. 10:375

Wagle, M., Nguyen, J., Lee, S., Zaitlen, N., Guo, S. (2017) Heritable natural variation of an anxiety-like behavior in larval zebrafish. Journal of neurogenetics. 31(3):138-148

Tong, K., Wagle, M., Guo, S. (2017) Antibody Uptake Assay in the Embryonic Zebrafish Forebrain to Study Notch Signaling Dynamics in Neural Progenitor Cells In Vivo. Methods in molecular biology (Clifton, N.J.).

Bai, Y., Liu, H., Huang, B., Wagle, M., Guo, S. (2016) Identification of environmental stressors and validation of light preference as a measure of anxiety in larval zebrafish. BMC Neuroscience. 17:63

Berberoglu, M.A., Dong, Z., Li, G., Zheng, J., Trejo Martinez, L.d.e.l. .C., Peng, J., Wagle, M., Reichholf, B., Petritsch, C., Li, H., Pleasure, S.J., Guo, S. (2014) Heterogeneously Expressed fezf2 Patterns Gradient Notch Activity in Balancing the Quiescence, Proliferation, and Differentiation of Adult Neural Stem Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:13911-23

Guo, S., Wagle, M., and Mathur, P. (2012) Toward molecular genetic dissection of neural circuits for emotional and motivational behaviors. Developmental Neurobiology. 72(3):358-365

Dong, Z., Wagle, M., and Guo, S. (2011) Time-lapse Live Imaging of Clonally Related Neural Progenitor Cells in the Developing Zebrafish Forebrain. Journal of visualized experiments : JoVE. (50)

Wagle, M., Mathur, P., and Guo, S. (2011) Corticotropin-releasing factor critical for zebrafish camouflage behavior is regulated by light and sensitive to ethanol. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(1):214-224

Peng, J., Wagle, M., Mueller, T., Mathur, P., Lockwood, B.L., Bretaud, S., and Guo, S. (2009) Ethanol-modulated camouflage response screen in zebrafish uncovers a novel role for cAMP and extracellular signal-regulated kinase signaling in behavioral sensitivity to ethanol. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(26):8408-8418

Wagle, M., Grunewald, B., Subburaju, S., Barzaghi, C., Le Guyader, S., Chan, J., and Jesuthasan, S. (2004) EphrinB2a in the zebrafish retinotectal system. Journal of neurobiology. 59(1):57-65

Wagle, M. and Jesuthasan, S. (2003) Baculovirus-mediated gene expression in zebrafish. Marine biotechnology (New York, N.Y.). 5(1):58-63

NON-ZEBRAFISH PUBLICATIONS
Yeo SC, Xu L, Ren J, Boulton VJ, Wagle MD, Liu C, Ren G, Wong P, Zahn R, Sasajala P, Yang H, Piper RC, Munn AL.
Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae.
J Cell Sci. 2003 Oct 1;116(Pt 19):3957-70.
PMID: 12953057

Wagle MD, Sen S, Rao BJ.
Local repeat sequence organization of an intergenic spacer in the chloroplast genome of Chlamydomonas reinhardtii leads to DNA expansion and sequence scrambling: a complex mode of 'copy-choice replication'?
J Biosci. 2001 Dec;26(5):583-94.
PMID: 11807289

Karthikeyan G, Lakshmikant GS, Wagle MD, Krishnamoorthy G, Rao BJ.
RecA interacts with Klenow and enhances fidelity of DNA synthesis in vitro.
J Mol Microbiol Biotechnol. 1999 Aug;1(1):149-56.
PMID: 10941797

Karthikeyan G, Wagle MD, Rao BJ.
Non-Watson-Crick base pairs modulate homologous alignments in RecA pairing reactions.
FEBS Lett. 1998 Mar 20;425(1):45-51.
PMID: 9541004