ZFIN ID: ZDB-PERS-050404-1
Zhao, Qingshun
Email: qingshun@nju.edu.cn
URL:
Affiliation: Zhao Lab
Address: Model Animal Research Center Nanjing University 308 Xuefu Road, Pukou District Nanjing, 210032 China
Country: China
Phone: +86 25 58641527
Fax: +86 25 58641500
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Li, N., Jiang, D., He, L., Yue, Y., Zhang, Q., Wang, S., Zhang, Y., Wei, Y., Zhao, Q. (2022) Both prokaryotes and eukaryotes produce an immune response against plasmids with 5'-GTTTGTT-3'. Cell & Bioscience. 12:87
Dong, X., Jiang, D., Wang, L., Zhao, J., Yu, L., Huang, Y., Wu, X., Zhu, Y., Zhao, Y., Zhao, Q., Zhang, G., Li, X. (2022) VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion. iScience. 25:104042
He, L., Zhang, Q., Jiang, D., Zhang, Y., Wei, Y., Yang, Y., Li, N., Wang, S., Yue, Y., Zhao, Q. (2021) Zebrafish foxc1a controls ventricular chamber maturation by directly regulating wwtr1 and nkx2.5 expression. Journal of genetics and genomics = Yi chuan xue bao. 49(6):559-568
Zhang, Y., Zhao, W., Chen, Y., Yuan, H., Fang, H., Yao, S., Zhang, C., Xu, H., Li, N., Liu, Z., Guo, Z., Zhao, Q., Liang, Y., He, W. (2021) Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo. Nature communications. 12:2772
Zhang, Q., Liang, D., Yue, Y., He, L., Li, N., Jiang, D., Hu, P., Zhao, Q. (2020) Axenfeld-Rieger syndrome-associated mutants of the transcription factor FOXC1 abnormally regulate NKX2-5 in model zebrafish embryos. The Journal of biological chemistry. 295(33):11902-11913
Jia, W., Liang, D., Li, N., Liu, M., Dong, Z., Li, J., Dong, X., Yue, Y., Hu, P., Yao, J., Zhao, Q. (2018) Zebrafish microRNA miR-210-5p inhibits primitive myelopoiesis by silencing foxj1b and slc3a2a mRNAs downstream of gata4/5/6 transcription factor genes. The Journal of biological chemistry. 294(8):2732-2743
Li, J., Zhao, Y., He, L., Huang, Y., Yang, X., Yu, L., Zhao, Q., Dong, X. (2018) Znfl1s are essential for patterning the anterior-posterior axis of zebrafish posterior hindbrain by acting as direct target genes of retinoic acid. Mechanisms of Development. 155:27-33
Li, J., Gao, F., Zhao, Y., He, L., Huang, Y., Yang, X., Zhou, Y., Yu, L., Zhao, Q., Dong, X. (2018) Zebrafish znfl1s regulate left-right asymmetry patterning through controlling the expression of fgfr1a. Journal of Cellular Physiology. 234(3):1987-1995
Zhou, L., Feng, Y., Wang, F., Dong, X., Jiang, L., Liu, C., Zhao, Q., Li, K. (2018) Generation of all-male-like sterile zebrafish by eliminating primordial germ cells at early development. Scientific Reports. 8:1834
Yue, Y., Jiang, M., He, L., Zhang, Z., Zhang, Q., Gu, C., Liu, M., Li, N., Zhao, Q. (2017) The transcription factor Foxc1a in zebrafish directly regulates expression of nkx2.5, encoding a transcriptional regulator of cardiac progenitor cells.. The Journal of biological chemistry. 293(2):638-650
Gong, J., Wang, X., Zhu, C., Dong, X., Zhang, Q., Wang, X., Duan, X., Qian, F., Shi, Y., Gao, Y., Zhao, Q., Chai, R., Liu, D. (2017) Insm1a Regulates Motor Neuron Development in Zebrafish. Frontiers in molecular neuroscience. 10:274
Dong, X., Li, J., He, L., Gu, C., Jia, W., Yue, Y., Li, J., Zhang, Q., Chu, L., Zhao, Q. (2017) Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes.. The Journal of biological chemistry. 292(31):13045-13055
Chen, X., Sheng, X., Zhuang, W., Sun, X., Liu, G., Shi, X., Huang, G., Mei, Y., Li, Y., Pan, X., Liu, Y., Li, Z., Zhao, Q., Yan, B., Zhao, C. (2017) GUCA1A mutation causes maculopathy in a five-generation family with a wide spectrum of severity. Genetics in medicine : official journal of the American College of Medical Genetics. 19(8):945-954
Zhu, Z., Zhao, Y., Li, J., Tao, L., Shi, P., Wei, Z., Sheng, X., Shen, D., Liu, Z., Zhou, L., Tian, C., Fan, F., Shen, C., Zhu, P., Wang, A., Chen, W., Zhao, Q., Lu, Y. (2016) Cryptotanshinone, a novel tumor angiogenesis inhibitor, destabilizes tumor necrosis factor-α mRNA via decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR. Molecular Carcinogenesis. 55(10):1399-410
Xu, S., Cao, S., Zou, B., Yue, Y., Gu, C., Chen, X., Wang, P., Dong, X., Xiang, Z., Li, K., Zhu, M., Zhao, Q., Zhou, G. (2016) An alternative novel tool for DNA editing without target sequence limitation: the structure-guided nuclease. Genome biology. 17:186
Li, J., Yue, Y., Zhao, Q. (2016) Retinoic Acid Signaling Is Essential for Valvulogenesis by Affecting Endocardial Cushions Formation in Zebrafish Embryos. Zebrafish. 13(1):9-18
Liu, Y., Chen, X., Xu, Q., Gao, X., Tam, P.O., Zhao, K., Zhang, X., Chen, L.J., Jia, W., Zhao, Q., Vollrath, D., Pang, C.P., Zhao, C. (2015) SPP2 Mutations Cause Autosomal Dominant Retinitis Pigmentosa. Scientific Reports. 5:14867
Li, J., Yue, Y., Dong, X., Jia, W., Li, K., Liang, D., Dong, Z., Wang, X., Nan, X., Zhang, Q., Zhao, Q. (2015) Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of aldh1a2 directly. The Journal of biological chemistry. 290(16):10216-28
Xu, T., Zhao, J., Yin, D., Zhao, Q., Dong, B. (2015) High-throughput RNA sequencing reveals the effects of 2,2',4,4' -tetrabromodiphenyl ether on retina and bone development of zebrafish larvae. BMC Genomics. 16:23
Liu, Y., Chen, X., Qin, B., Zhao, K., Zhao, Q., Staley, J.P., Zhao, C. (2015) Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish. Journal of ophthalmology. 2015:816329
Li, J., Li, K., Dong, X., Liang, D., Zhao, Q. (2014) Ncor1 and Ncor2 Play essential but distinct roles in zebrafish primitive myelopoiesis. Developmental dynamics : an official publication of the American Association of Anatomists. 243(12):1544-53
Dong, Z., Dong, X., Jia, W., Cao, S., Zhao, Q. (2014) Improving the efficiency for generation of genome-edited zebrafish by labeling primordial germ cells. The international journal of biochemistry & cell biology. 55:329-34
Xu, T., Zhao, J., Hu, P., Dong, Z., Li, J., Zhang, H., Yin, D., Zhao, Q. (2014) Pentachlorophenol exposure causes Warburg-like effects in zebrafish embryos at gastrulation stage. Toxicology and applied pharmacology. 277:183-91
Chen, X., Liu, Y., Sheng, X., Tam, P.O., Zhao, K., Chen, X., Rong, W., Liu, Y., Liu, X., Pan, X., Chen, L.J., Zhao, Q., Vollrath, D., Pang, C.P., and Zhao, C. (2014) PRPF4 mutations cause autosomal dominant retinitis pigmentosa. Human molecular genetics. 23(11):2926-39
Dong, Z., Ge, J., Xu, Z., Dong, X., Cao, S., Pan, J., Zhao, Q. (2014) Generation of Myostatin b Knockout Yellow Catfish (Tachysurus Fulvidraco) Using Transcription Activator-Like Effector Nucleases. Zebrafish. 11(3):265-74
Li, J., Jia, W., Zhao, Q. (2014) Excessive nitrite affects zebrafish valvulogenesis through yielding too much NO signaling. PLoS One. 9:e92728
He, Q., Wang, L., Wang, F., Wang, C., Tang, C., Li, Q., Li, J., and Zhao, Q. (2013) Microbial fingerprinting detects intestinal microbiota dysbiosis in Zebrafish models with chemically-induced enterocolitis. BMC microbiology. 13:289
Li, J., Hu, P., Li, K., and Zhao, Q. (2012) Identification and Characterization of a Novel Retinoic Acid Response Element in Zebrafish cyp26a1 Promoter. The Anatomical record. 295(2):268-77
Liang, D., Jia, W., Li, J., Li, K., and Zhao, Q. (2012) Retinoic Acid signaling plays a restrictive role in zebrafish primitive myelopoiesis. PLoS One. 7(2):e30865
Chen, Q., Huang, S., Zhao, Q., Chen, R., and Zhang, A. (2011) Expression and function of the Ets transcription factor pea3 during formation of zebrafish pronephros. Pediatric nephrology (Berlin, Germany). 26(3):391-400
Dong, Z., Ge, J., Li, K., Xu, Z., Liang, D., Li, J., Li, J., Jia, W., Li, Y., Dong, X., Cao, S., Wang, X., Pan, J., and Zhao, Q. (2011) Heritable Targeted Inactivation of Myostatin Gene in Yellow Catfish (Pelteobagrus fulvidraco) Using Engineered Zinc Finger Nucleases. PLoS One. 6(12):e28897
Xu, F., Li, K., Tian, M., Hu, P., Song, W., Chen, J., Gao, X., and Zhao, Q. (2009) N-CoR is required for patterning the anterior-posterior axis of zebrafish hindbrain by actively repressing retinoid signaling. Mechanisms of Development. 126(10):771-780
Yin, D., Zhu, H., Hu, P., and Zhao, Q. (2009) Genotoxic effect of 2,4,6-trichlorophenol on p53 gene in zebrafish liver. Environmental toxicology and chemistry. 28(3):603-608
Hu, P., Tian, M., Bao, J., Xing, G., Gu, X., Gao, X., Linney, E., and Zhao, Q. (2008) Retinoid regulation of the zebrafish cyp26a1 promoter. Developmental dynamics : an official publication of the American Association of Anatomists. 237(12):3798-3808
Liang, D., Zhang, M., Bao, J., Zhang, L., Xu, X., Gao, X., and Zhao, Q (2008) Expressions of Raldh3 and Raldh4 during zebrafish early development. Gene expression patterns : GEP. 8(4):248-253
Yin, D., Gu, Y., Li, Y., Wang, X., and Zhao, Q. (2006) Pentachlorophenol treatment in vivo elevates point mutation rate in zebrafish p53 gene. Mutation research. 609(1):92-101
Yao, J., Wang, L., Chen, L., Zhang, S., Zhao, Q., Jia, W., and Xue, J. (2006) Cloning and developmental expression of the DEC1 ortholog gene in zebrafish. Gene expression patterns : GEP. 6(8):919-927
Song, W., Zou, Z., Xu, F., Gu, X., Xu, X., and Zhao, Q. (2006) Molecular cloning and expression of a second zebrafish aldehyde dehydrogenase 2 gene (aldh2b). DNA sequence : the journal of DNA sequencing and mapping. 17(4):262-269
Gu, X., Xu, F., Song, W., Wang, X., Hu, P., Yang, Y., Gao, X., and Zhao, Q. (2006) A Novel Cytochrome P450, Zebrafish Cyp26D1, Is Involved in Metabolism of All-trans Retinoic Acid. Molecular endocrinology (Baltimore, Md.). 20(7):1661-1672
Gu, X., Xu, F., Wang, X., Gao, X., and Zhao, Q. (2005) Molecular cloning and expression of a novel CYP26 gene (cyp26d1) during zebrafish early development. Gene expression patterns : GEP. 5(6):733-739
Zhao, Q., Dobbs-McAuliffe, B., and Linney, E. (2005) Expression of cyp26b1 during zebrafish early development. Gene expression patterns : GEP. 5(3):363-369
Sun, L., Zou, Z., Collodi, P., Xu, F., Xu, X., and Zhao, Q. (2005) Identification and characterization of a second fibronectin gene in zebrafish. Matrix biology : journal of the International Society for Matrix Biology. 24(1):69-77
Dobbs-McAuliffe, B., Zhao, Q., and Linney, E. (2004) Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo. Mechanisms of Development. 121(4):339-350
Liu, X., Zhao, Q., and Collodi, P. (2003) A truncated form of fibronectin is expressed in fish and mammals. Matrix biology : journal of the International Society for Matrix Biology. 22(5):393-396
Zhao, Q., Liu, X., and Collodi, P. (2001) Identification and characterization of a novel fibronectin in zebrafish. Experimental cell research. 268(2):211-219

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