ZFIN Person: Allison, Ted

ZFIN ID: ZDB-PERS-050304-1

ZFIN ID: ZDB-PERS-050304-1

Allison, Ted

Email:	ted.allison@ualberta.ca
URL:	http://www.biology.ualberta.ca/allison_lab/
Affiliation:	Allison Lab
Address:	Department of Biological Sciences & Centre for Prions and Protein Folding Diseases G-315, Biological Sciences Centre University of Alberta Edmonton, Alberta, T6G 2E9 Canada
Country:	Canada
Phone:	(780) 492-4430
Fax:	(780) 492-9234
ORCID ID:	0000-0002-8461-4864

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Neil, G.J., Kluttig, K.H., Allison, W.T. (2024) Determining Photoreceptor Cell Identity: Rod Versus Cone Fate Governed by tbx2b Opposing nrl. Investigative ophthalmology & visual science. 65:3939

Gill, T., Locskai, L.F., Burton, A.H., Alyenbaawi, H., Wheeler, T., Burton, E.A., Allison, W.T. (2024) Delivering Traumatic Brain Injury to Larval Zebrafish. Methods in molecular biology (Clifton, N.J.). 2707:3223-22

Hodges, E.D., Chrystal, P.W., Footz, T., Doucette, L.P., Noel, N.C.L., Li, Z., Walter, M.A., Allison, W.T. (2023) Disrupting the Repeat Domain of Premelanosome Protein (PMEL) Produces Dysamyloidosis and Dystrophic Ocular Pigment Reflective of Pigmentary Glaucoma. International Journal of Molecular Sciences. 24(19):

Kanyo, R., Lamothe, S.M., Urrutia, A., Goodchild, S.J., Allison, W.T., Dean, R., Kurata, H.T. (2023) Site and Mechanism of ML252 Inhibition of Kv7 Voltage-Gated Potassium Channels. Function (Oxford, England). 4:zqad021zqad021

Chrystal, P.W., Lambacher, N.J., Doucette, L.P., Bellingham, J., Schiff, E.R., Noel, N.C.L., Li, C., Tsiropoulou, S., Casey, G.A., Zhai, Y., Nadolski, N.J., Majumder, M.H., Tagoe, J., D'Esposito, F., Cordeiro, M.F., Downes, S., Clayton-Smith, J., Ellingford, J., Genomics England Research Consortium, Mahroo, O.A., Hocking, J.C., Cheetham, M.E., Webster, A.R., Jansen, G., Blacque, O.E., Allison, W.T., Au, P.Y.B., MacDonald, I.M., Arno, G., Leroux, M.R. (2022) The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision. Nature communications. 13:6595

Pollock, N.M., Leighton, P., Neil, G., Allison, W.T. (2021) Transcriptomic analysis of zebrafish prion protein mutants supports conserved cross-species function of the cellular prion protein. Prion. 15:70-81

Kanyo, R., Amin, M.R., Locskai, L.F., Bouvier, D.D., Olthuis, A.M., Allison, W.T., Ali, D.W. (2021) Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ⁹-tetrahydrocannabinol. Scientific Reports. 11:11515

Alyenbaawi, H., Kanyo, R., Locskai, L.F., Kamali-Jamil, R., DuVal, M.G., Bai, Q., Wille, H., Burton, E.A., Allison, W.T. (2021) Seizures are a druggable mechanistic link between TBI and subsequent tauopathy. eLIFE. 10:

Noel, N.C.L., MacDonald, I.M., Allison, W.T. (2021) Zebrafish Models of Photoreceptor Dysfunction and Degeneration. Biomolecules. 11(1):

Oel, A.P., Neil, G.J., Dong, E.M., Balay, S.D., Collett, K., Allison, W.T. (2020) Nrl Is Dispensable for Specification of Rod Photoreceptors in Adult Zebrafish Despite Its Deeply Conserved Requirement Earlier in Ontogeny. iScience. 23:101805

Noel, N.C.L., Nadolski, N.J., Hocking, J.C., MacDonald, I.M., Allison, W.T. (2020) Progressive Photoreceptor Dysfunction and Age-Related Macular Degeneration-Like Features in rp1l1 Mutant Zebrafish. Cells. 9(10):

Özcan, G.G., Lim, S., Leighton, P., Allison, W.T., Rihel, J. (2020) Sleep is bi-directionally modified by amyloid beta oligomers. eLIFE. 9:

Kanyo, R., Wang, C.K., Locskai, L.F., Li, J., Allison, W.T., Kurata, H.T. (2020) Functional and behavioral signatures of Kv7 activator drug subtypes. Epilepsia. 61(8):1678-1690

Zarowny, L., Aggarwal, A., Rutten, V.M.S., Kolb, I., Project, T.G., Patel, R., Huang, H.Y., Chang, Y.F., Phan, T., Kanyo, R., Ahrens, M.B., Allison, W.T., Podgorski, K., Campbell, R.E. (2020) A bright and high-performance genetically encoded Ca2+ indicator based on mNeonGreen fluorescent protein. ACS sensors. 5(7):1959-1968

Miyashita, T., Baddam, P., Smeeton, J., Oel, A.P., Natarajan, N., Gordon, B., Palmer, A.R., Crump, J.G., Graf, D., Allison, W.T. (2020) nkx3.2 mutant zebrafish accommodate jaw joint loss through a phenocopy of the head shapes of Paleozoic jawless fish. The Journal of experimental biology. 223(Pt 15):

Kanyo, R., Leighton, P.L.A., Neil, G.J., Locskai, L.F., Allison, W.T. (2020) Amyloid-β precursor protein mutant zebrafish exhibit seizure susceptibility that depends on prion protein. Experimental neurology. 328:113283

Sufian, M.S., Amin, M.R., Kanyo, R., Allison, W.T., Ali, D.W. (2019) CB₁ and CB₂ receptors play differential roles in early zebrafish locomotor development. The Journal of experimental biology. 222(Pt 16)

Lahola-Chomiak, A.A., Footz, T., Nguyen-Phuoc, K., Neil, G.J., Fan, B., Allen, K.F., Greenfield, D.S., Parrish, R.K., Linkroum, K., Pasquale, L.R., Leonhardt, R.M., Ritch, R., Javadiyan, S., Craig, J.E., Ted Allison, W., Lehmann, O.J., Walter, M.A., Wiggs, J.L. (2018) Non-Synonymous variants in Premelanosome Protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma. Human molecular genetics. 28(8):1298-1311

DuVal, M.G., Allison, W.T. (2018) Photoreceptor Progenitors Depend Upon Coordination of gdf6a, thrβ, and tbx2b to Generate Precise Populations of Cone Photoreceptor Subtypes. Investigative ophthalmology & visual science. 59:6089-6101

Leighton, P.L.A., Kanyo, R., Neil, G.J., Pollock, N.M., Allison, W.T. (2018) Prion gene paralogs are dispensable for early zebrafish development but have non-additive roles in seizure susceptibility. The Journal of biological chemistry. 293(32):12576-12592

Leighton, P.L.A., Nadolski, N.J., Morrill, A., Hamilton, T.J., Allison, W.T. (2018) An ancient conserved role for prion protein in learning and memory. Biology Open. 7(1)

Noel, N.C.L., Allison, W.T. (2017) Connectivity of cone photoreceptor telodendria in the zebrafish retina. The Journal of comparative neurology. 526(4):609-625

DuVal, M.G., Allison, W.T. (2017) Impacts of the retinal environment and photoreceptor type on functional regeneration. Neural regeneration research. 12:376-379

Hagerman, G.F., Noel, N.C., Cao, S.Y., DuVal, M.G., Oel, A.P., Allison, W.T. (2016) Rapid Recovery of Visual Function Associated with Blue Cone Ablation in Zebrafish. PLoS One. 11:e0166932

Hanwell, D., Hutchinson, S.A., Collymore, C., Bruce, A.E., Louis, R., Ghalami, A., Allison, W.T., Ekker, M., Eames, B.F., Childs, S., Kurrasch, D.M., Gerlai, R., Thiele, T., Scott, I., Ciruna, B., Dowling, J.J., McFarlane, S., Huang, P., Wen, X.Y., Akimenko, M.A., Waskiewicz, A.J., Drapeau, P., Babiuk, L.A., Dragon, D., Smida, A., Buret, A.G., O'Grady, E., Wilson, J., Sowden-Plunkett, L., Tropepe, V. (2016) Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus. Zebrafish. 13 Suppl 1:S153-63

Kim, J.W., Yang, H.J., Oel, A.P., Brooks, M.J., Jia, L., Plachetzki, D.C., Li, W., Allison, W.T., Swaroop, A. (2016) Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals. Developmental Cell. 37:520-532

Huc-Brandt, S., Hieu, N., Imberdis, T., Cubedo, N., Silhol, M., Leighton, P.L., Domaschke, T., Allison, W.T., Perrier, V., Rossel, M. (2014) Zebrafish Prion Protein PrP2 Controls Collective Migration Process during Lateral Line Sensory System Development. PLoS One. 9:e113331

Yoshimatsu, T., Williams, P.R., D'Orazi, F.D., Suzuki, S.C., Fadool, J.M., Allison, W.T., Raymond, P.A., Wong, R.O. (2014) Transmission from the dominant input shapes the stereotypic ratio of photoreceptor inputs onto horizontal cells. Nature communications. 5:3699

Duval, M.G., Oel, A.P., Allison, W.T. (2014) gdf6a is required for cone photoreceptor subtype differentiation and for the actions of tbx2b in determining rod versus cone photoreceptor fate. PLoS One. 9:e92991

DuVal, M.G., Gilbert, M.J., Watson, D.E., Zerulla, T.C., Tierney, K.B., Allison, W.T. (2014) Growth differentiation factor 6 as a putative risk factor in neuromuscular degeneration. PLoS One. 9:e89183

Pillay, L.M., Selland, L.G., Fleisch, V.C., Leighton, P.L., Cheng, C.S., Famulski, J.K., Ritzel, R.G., March, L.D., Wang, H., Allison, W.T., and Waskiewicz, A.J. (2013) Evaluating the Mutagenic Activity of Targeted Endonucleases Containing a Sharkey FokI Cleavage Domain Variant in Zebrafish. Zebrafish. 10(3):353-64

Fleisch, V.C., Leighton, P.L., Wang, H., Pillay, L.M., Ritzel, R.G., Bhinder, G., Roy, B., Tierney, K.B., Ali, D.W., Waskiewicz, A.J., and Allison, W.T. (2013) Targeted Mutation of the Gene Encoding Prion Protein in Zebrafish reveals a Conserved Role in Neuron Excitability. Neurobiology of disease. 55:11-25

Duval, M.G., Chung, H., Lehmann, O.J., and Allison, W.T. (2013) Longitudinal fluorescent observation of retinal degeneration and regeneration in zebrafish using fundus lens imaging. Molecular Vision. 19:1082-1095

Asai-Coakwell, M., March, L., Dai, X.H., Duval, M., Lopez, I., French, C.R., Famulski, J., De Baere, E., Francis, P.J., Sundaresan, P., Sauvé, Y., Koenekoop, R.K., Berry, F.B., Allison, W.T., Waskiewicz, A.J., and Lehmann, O.J. (2013) Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies. Human molecular genetics. 22(7):1432-1442

Fraser, B., Duval, M.G., Wang, H., and Allison, W.T. (2013) Regeneration of cone photoreceptors when cell ablation is primarily restricted to a particular cone subtype. PLoS One. 8(1):e55410

Kaiser, D.M., Acharya, M., Leighton, P.L., Wang, H., Daude, N., Wohlgemuth, S., Shi, B., and Allison, W.T. (2012) Amyloid Beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS development. PLoS One. 7(12):e51305

Acharya, M., Huang, L., Fleisch, V.C., Allison, W.T., and Walter, M.A. (2011) A Complex Regulatory Network of Transcription Factors Critical for Ocular Development and Disease. Human molecular genetics. 20(8):1610-24

Fleisch, V.C., Fraser, B., and Allison, W.T. (2011) Investigating regeneration and functional integration of CNS neurons: Lessons from zebrafish genetics and other fish species. Biochimica et biophysica acta. Molecular basis of disease. 1812(3):364-380

Allison, W.T. (2011) Preface to BBA: Molecular basis of disease special issue - Zebrafish models of neurology. Biochimica et biophysica acta. Molecular basis of disease. 1812(3):333-334

Allison, W.T., Barthel, L.K., Skebo, K.M., Takechi, M., Kawamura, S., and Raymond, P.A. (2010) Ontogeny of cone photoreceptor mosaics in zebrafish. The Journal of comparative neurology. 518(20):4182-4195

Ye, M., Berry-Wynne, K.M., Asai-Coakwell, M., Sundaresan, P., Footz, T., French, C.R., Abitbol, M., Fleisch, V.C., Corbett, N., Allison, W.T., Drummond, G., Walter, M.A., Underhill, T.M., Waskiewicz, A.J., and Lehmann, O.J. (2010) Mutation of the Bone Morphogenetic Protein GDF3 causes ocular and skeletal anomalies. Human molecular genetics. 19(2):287-298

Allison, W.T., Haimberger, T.J., Hawryshyn, C.W., and Temple, S.E. (2004) Visual pigment composition in zebrafish: Evidence for a rhodopsin-porphyropsin interchange system. Visual neuroscience. 21(6):945-952

NON-ZEBRAFISH PUBLICATIONS
Owens, G.L., Rennison, D.J., Allison, W.T., Taylor, J.S. (2012) Distinct spatial expression domains of opsins in the retina of the four-eyed fish, an exaggeration of patterns found in surface-dwelling species. Biology Letters. 8:86-9.

Rennison, D.J., Owens, G.L., Allison, W.T., Taylor, J.S. (2011) Intra-retinal variation of opsin gene expression in the guppy (Poecilia reticulata). Journal of Experimental Biology. 214:3248-54.

Allison, W.T., Dann, S.G., Veldhoen, K.M. and Hawryshyn, C.W. (2006) Degeneration and regeneration of ultraviolet cone photoreceptors during development in rainbow trout. Journal of Comparative Neurology 499: 702-715.

Allison, W.T., Veldhoen, K.M. and Hawryshyn, C.W. (2006) Proteomic analysis of opsins and thyroid hormone-induced retinal development using isotope-coded affinity tags (ICAT) and mass spectrometry." Molecular Vision 12:655-672.

Allison, W.T., Hallows, T.E., Johnson, T., Hawryshyn, C.W. and Allen, D.M. (2006) Photic history modifies susceptibility to retinal damage in albino trout. Visual Neuroscience 23:25-34.

Veldhoen, K., Allison, W.T., Veldhoen, N., Anholt, B.R., Helbing, C.C. and Hawryshyn, C.W. (2006) Spatio-temporal characterization of retinal opsin gene expression during thyroid hormone-induced and natural development of rainbow trout." Visual Neuroscience 23:169�179.

Dann, S.G., Allison, W.T., Levin, D.B., Taylor, J.S. & Hawryshyn, C.W. (2004). Salmonid opsin sequences undergo positive selection and indicate an alternate evolutionary relationship in Oncorhynchus. Journal of Molecular Evolution 58, 400-412.

Dann, S.G., Allison, W.T., Veldhoen, K., Johnson, T. & Hawryshyn, C.W. (2004). Chromatin immunoprecipitation assay on the rainbow trout opsin proximal promoters illustrates binding of NF-kB and c-jun to the SWS1 promoter in the retina. Experimental Eye Research 78, 1015-1024.

Allison, W.T., Dann, S.G., Helvik, J.V., Bradley, C., Moyer, H.D. & Hawryshyn, C.W. (2003). Ontogeny of ultraviolet-sensitive cones in the retina of rainbow trout (Oncorhynchus mykiss). Journal of Comparative Neurology 461, 294-306.

Dann, S.G., Allison, W.T., Levin, D.B. & Hawryshyn, C.W. (2003). Identification of a unique transcript down-regulated in the retina of rainbow trout (Oncorhynchus mykiss) at smoltification. Comparative Biochemistry and Physiology. Part B, Biochemistry and Molecular Biology, 849-860.

Hawryshyn, C.W., Martens, G., Allison, W.T. & Anholt, B.R. (2003). Regeneration of ultraviolet-sensitive cones in the retinal cone mosaic of thyroxin-challenged post-juvenile rainbow trout (Oncorhynchus mykiss). Journal of Experimental Biology 206, 2665-2673.

Hawryshyn, C.W., Moyer, H.D., Allison, W.T., Haimberger, T.J. & McFarland, W.N. (2003). Multidimensional polarization sensitivity in damselfishes. Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology 189, 213-220.

Plate, E.M., Adams, B.A., Allison, W.T., Martens, G., Hawryshyn, C.W. & Eales, J.G. (2002). The effects of thyroxine or a GnRH analogue on thyroid hormone deiodination in the olfactory epithelium and retina of rainbow trout, Oncorhynchus mykiss, and sockeye salmon, Oncorhynchus nerka. General and Comparative Endocrinology 127, 59-65.