ZFIN Person: Winata, Cecilia Lanny

ZFIN ID: ZDB-PERS-040812-3

Winata, Cecilia Lanny

Email:	cwinata@iimcb.gov.pl
URL:	http://www.iimcb.gov.pl/en/research/laboratories/8-laboratory-of-zebrafish-developmental-genomics-winata-laboratory-max-planck-iimcb-research-group#tab1
Affiliation:	Laboratory of Zebrafish Developmental Genomics
Address:	Laboratory of Zebrafish Developmental Genomics International Institute of Molecular and Cell Biology in Warsaw Ks. J. Trojdena 4 02-109 Warsaw
Country:	Poland
Phone:	+ 48 22 597 07 68
Fax:	+ 48 22 597 07 15
ORCID ID:	0000-0002-7718-5248

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Niescierowicz, K., Pryszcz, L., Navarrete, C., Tralle, E., Sulej, A., Abu Nahia, K., Kasprzyk, M.E., Misztal, K., Pateria, A., Pakuła, A., Bochtler, M., Winata, C. (2022) Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish. Nature communications. 13:5520

Bartoszewski, S., Dawidziuk, M., Kasica, N., Durak, R., Jurek, M., Podwysocka, A., Guilbride, D.L., Podlasz, P., Winata, C.L., Gawlinski, P. (2022) A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly. Cells. 11(17)

Baranasic, D., Hörtenhuber, M., Balwierz, P.J., Zehnder, T., Mukarram, A.K., Nepal, C., Várnai, C., Hadzhiev, Y., Jimenez-Gonzalez, A., Li, N., Wragg, J., D'Orazio, F.M., Relic, D., Pachkov, M., Díaz, N., Hernández-Rodríguez, B., Chen, Z., Stoiber, M., Dong, M., Stevens, I., Ross, S.E., Eagle, A., Martin, R., Obasaju, O., Rastegar, S., McGarvey, A.C., Kopp, W., Chambers, E., Wang, D., Kim, H.R., Acemel, R.D., Naranjo, S., Łapiński, M., Chong, V., Mathavan, S., Peers, B., Sauka-Spengler, T., Vingron, M., Carninci, P., Ohler, U., Lacadie, S.A., Burgess, S.M., Winata, C., van Eeden, F., Vaquerizas, J.M., Gómez-Skarmeta, J.L., Onichtchouk, D., Brown, B.J., Bogdanovic, O., van Nimwegen, E., Westerfield, M., Wardle, F.C., Daub, C.O., Lenhard, B., Müller, F. (2022) Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements. Nature Genetics. 54(7):1037-1050

Migdał, M., Tralle, E., Nahia, K.A., Bugajski, Ł., Kędzierska, K.Z., Garbicz, F., Piwocka, K., Winata, C.L., Pawlak, M. (2021) Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift. BMC Genomics. 22:904

Minhas, R., Loeffler-Wirth, H., Siddiqui, Y.H., Obrębski, T., Vashisht, S., Nahia, K.A., Paterek, A., Brzozowska, A., Bugajski, L., Piwocka, K., Korzh, V., Binder, H., Winata, C.L. (2021) Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker. BMC Genomics. 22:715

Abu Nahia, K., Migdał, M., Quinn, T.A., Poon, K.L., Łapiński, M., Sulej, A., Liu, J., Mondal, S.S., Pawlak, M., Bugajski, Ł., Piwocka, K., Brand, T., Kohl, P., Korzh, V., Winata, C. (2021) Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region. Cellular and molecular life sciences : CMLS. 78(19-20):6669-6687

Korzh, S., Winata, C.L., Gong, Z., Korzh, V. (2021) The development of zebrafish pancreas affected by deficiency of Hedgehog signaling. Gene expression patterns : GEP. 41:119185

Parisi, C., Vashisht, S., Winata, C.L. (2021) Fish-Ing for Enhancers in the Heart. International Journal of Molecular Sciences. 22(8):

Fricke, T., Smalakyte, D., Lapinski, M., Pateria, A., Weige, C., Pastor, M., Kolano, A., Winata, C., Siksnys, V., Tamulaitis, G., Bochtler, M. (2020) Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish. The CRISPR journal. 3:299-313

Winata, C.L., Dodzian, J., Bialek-Wyrzykowska, U. (2019) The zebrafish as a model for developmental and biomedical research in Poland and beyond. Developmental Biology. 457(2):167-168

Minhas, R., Paterek, A., Łapiński, M., Bazała, M., Korzh, V., Winata, C.L. (2019) A novel conserved enhancer at zebrafish zic3 and zic6 loci drives neural expression. Developmental dynamics : an official publication of the American Association of Anatomists. 248(9):837-849

Pawlak, M., Kedzierska, K.Z., Migdal, M., Nahia, K.A., Ramilowski, J.A., Bugajski, L., Hashimoto, K., Marconi, A., Piwocka, K., Carninci, P., Winata, C.L. (2019) Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development. Genome research. 29(3):506-519

Winata, C.L., Korzh, V. (2018) Zebrafish Zic Genes Mediate Developmental Signaling. Advances in experimental medicine and biology. 1046:157-177

Winata, C.L., Łapiński, M., Pryszcz, L., Vaz, C., Bin Ismail, M.H., Nama, S., Hajan, H.S., Lee, S.G.P., Korzh, V., Sampath, P., Tanavde, V., Mathavan, S. (2017) Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal to zygotic transition. Development (Cambridge, England). 145(1)

Aksoy, I., Utami, K.H., Winata, C.L., Hillmer, A.M., Rouam, S.L., Briault, S., Davila, S., Stanton, L.W., Cacheux, V. (2017) Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders. Human molecular genetics. 26:367-382

Tan, H., Onichtchouk, D., Winata, C. (2016) DANIO-CODE: Toward an Encyclopedia of DNA Elements in Zebrafish. Zebrafish. 13(1):54-60

Kraus, P., Winata, C.L., Lufkin, T. (2015) BAC Transgenic Zebrafish for Transcriptional Promoter and Enhancer Studies. Methods in molecular biology (Clifton, N.J.). 1227:245-58

Utami, K.H., Winata, C.L., Hillmer, A.M., Aksoy, I., Long, H.T., Liany, H., Yan, E.C., Mathavan, S., Hong, S.T., Korzh, V., Sarda, P., Davila, S., Cacheux, V. (2014) Impaired Development Of Neural-Crest Cell Derived Organs and Intellectual Disability Caused By MED13L Haploinsufficiency. Human Mutation. 35(11):1311-20

Aanes, H., Winata, C., Moen, L.F., Østrup, O., Mathavan, S., Collas, P., Rognes, T., and Aleström, P. (2014) Normalization of RNA-sequencing data from samples with varying mRNA levels. PLoS One. 9(2):e89158

Winata, C.L., Kondrychyn, I., Kumar, V., Srinivasan, K.G., Orlov, Y., Ravishankar, A., Prabhakar, S., Stanton, L.W., Korzh, V., and Mathavan, S. (2013) Genome wide analysis reveals zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish. PLoS Genetics. 9(10):e1003852

Lindeman, L.C., Andersen, I.S., Reiner, A.H., Li, N., Aanes, H., Ostrup, O., Winata, C., Mathavan, S., Muller, F., Aleström, P., and Collas, P. (2011) Prepatterning of Developmental Gene Expression by Modified Histones before Zygotic Genome Activation. Developmental Cell. 21(6):993-1004

Korzh, S., Winata, C.L., Zheng, W., Yang, S., Yin, A., Ingham, P., Korzh, V., and Gong, Z. (2011) The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development. Developmental Biology. 359(2):262-76

Aanes, H., Winata, C.L., Lin, C.H., Chen, J.P., Srinivasan, K.G., Lee, S.G., Lim, A.Y., Hajan, H.S., Collas, P., Bourque, G., Gong, Z., Korzh, V., Aleström, P., and Mathavan, S. (2011) Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. Genome research. 21(8):1328-38

Yin, A., Korzh, S., Winata, C.L., Korzh, V., and Gong, Z. (2011) Wnt signaling is required for early development of zebrafish swimbladder. PLoS One. 6(3):e18431

Ung, C.Y., Lam, S.H., Hlaing, M.M., Winata, C.L., Korzh, S., Mathavan, S., and Gong, Z. (2010) Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation. BMC Genomics. 11:212

Winata, C.L., Korzh, S., Kondrychyn, I., Korzh, V., and Gong, Z. (2010) The role of vasculature and blood circulation in zebrafish swimbladder development. BMC Developmental Biology. 10:3

Lindeman, L.C., Winata, C.L., Aanes, H., Mathavan, S., Alestrom, P., and Collas, P. (2010) Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos. The International journal of developmental biology. 54(5):803-813

Winata, C.L., Korzh, S., Kondrychyn, I., Zheng, W., Korzh, V., and Gong, Z. (2009) Development of zebrafish swimbladder: the requirement of Hedgehog signaling in specification and organization of the three tissue layers. Developmental Biology. 331(2):222-236

Korzh, S., Pan, X., Garcia-Lecea, M., Winata, C.L., Pan, X., Wohland, T., Korzh, V., and Gong, Z. (2008) Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish. BMC Developmental Biology. 8(1):84

Lam, S.H., Winata, C.L., Tong, Y., Korzh, S., Lim, W.S., Korzh, V., Spitsbergen, J., Mathavan, S., Miller, L.D., Liu, E.T., and Gong, Z. (2006) Transcriptome Kinetics of Arsenic-induced Adaptive Response in Zebrafish Liver. Physiological Genomics. 27(3):351-361

NON-ZEBRAFISH PUBLICATIONS