ZFIN Person: Laue, Kathrin

ZFIN ID: ZDB-PERS-031215-6

ZFIN ID: ZDB-PERS-031215-6

Laue, Kathrin

Email:	kathrinjulialaue@gmail.com
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BIOGRAPHY AND RESEARCH INTERESTS

Epigenetics, Chromatin, Developmental Biology, Aging, Metabolism

PUBLICATIONS

Calvird, A.E., Broniec, M.N., Duval, K.L., Higgs, A.N., Arora, V., Ha, L.N., Schouten, E.B., Crippen, A.R., McGrail, M., Laue, K., Goll, M.G. (2022) Uncovering Regulators of Heterochromatin Mediated Silencing Using a Zebrafish Transgenic Reporter. Frontiers in cell and developmental biology. 10:832461

Laue, K., Rajshekar, S., Courtney, A.J., Lewis, Z.A., Goll, M.G. (2019) The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo. Nature communications. 10:1551

Laue, K., Pogoda, H.M., Daniel, P.B., van Haeringen, A., Alanay, Y., von Ameln, S., Rachwalski, M., Morgan, T., Gray, M.J., Breuning, M.H., Sawyer, G.M., Sutherland-Smith, A.J., Nikkels, P.G., Kubisch, C., Bloch, W., Wollnik, B, Hammerschmidt, M., and Robertson, S.P. (2011) Craniosynostosis and Multiple Skeletal Anomalies in Humans and Zebrafish Result from a Defect in the Localized Degradation of Retinoic Acid. American journal of human genetics. 89(5):595-606

Li, Y., Laue, K., Temtamy, S., Aglan, M., Kotan, L.D., Yigit, G., Canan, H., Pawlik, B., Nürnberg, G., Wakeling, E.L., Quarrell, O.W., Baessmann, I., Lanktree, M.B., Yilmaz, M., Hegele, R.A., Amr, K., May, K.W., Nürnberg, P., Topaloglu, A.K., Hammerschmidt, M., and Wollnik, B. (2010) Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling. American journal of human genetics. 87(6):757-767

Laue, K., Jänicke, M., Plaster, N., Sonntag, C., and Hammerschmidt, M. (2008) Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development. Development (Cambridge, England). 135(22):3775-3787

Laue, K., Daujat, S., Crump, J.G., Plaster, N., Roehl, H.H., Tübingen 2000 Screen Consortium, Kimmel, C.B., Schneider, R., and Hammerschmidt, M. (2008) The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development (Cambridge, England). 135(11):1935-1946

NON-ZEBRAFISH PUBLICATIONS
Mera P, Laue, K, Wei J, Berger J, Karsenty G. Osteocalcin is necessary and sufficient to maintain muscle mass in older mice.
Molecular Metabolism, 1-6, 18 July 2016.

Mera P, Laue, K, Ferron M, Confavreux C, Wei J, Galan-Diaz M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, deCabo R, Friedman RA, Torsitano C, Mc Graw TE, Puchowicz M, Kurland I, Karsenty G. Osteocalcin signalling in myofibers is necessary and sufficient for optimum adaptation to exercise.
Cell Metabolism, 2016 June 14; 23 (6): 1078-92.

Mera P, Laue, K, Karsenty G. Osteocalcin regulates muscle function and mass.
J Bone Miner Res, 29: S50.