ZFIN ID: ZDB-PERS-030818-2
Hsu, Todd
Email: toddhsu@mail.ntou.edu.tw
URL: http://www.ntou.edu.tw
Affiliation:
Address: Institute of Bioscience and Biotechnology National Taiwan Ocean University 2, Pei-Ning Road Keelung Taiwan, 20224 Taiwan
Country:
Phone: 886-2-2462-2192 ext. 5503 or 5512
Fax: 886-2-2462-2320
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS
Studying developmental stage-dependent regulation of DNA repair gene expressions in zebrafish and the controlling mechanism of spontaneous heat shock protein 70 (HSP 70) expression in developing zebrafish.


PUBLICATIONS
Huang, Y.Y., Paul, G.V., Hsu, T. (2023) Thallium(I) induces a prolonged inhibition of (6-4)photoproduct binding and UV damage excision repair activities in zebrafish (Danio rerio) embryos via protein inactivation. Chemico-biological interactions. 388:110837
Paul, G.V., Sihite, A.C., Hsu, T. (2023) Susceptibility of DNA damage recognition activities linked to nucleotide excision and mismatch repair in zebrafish (Danio rerio) early and mid-early embryos to 2.5 to 4.5 °C heat stress. Fish physiology and biochemistry. 49(3):515-527
Paul, G.V., Huang, Y.Y., Wu, Y.N., Ho, T.N., Hsiao, H.I., Hsu, T. (2022) Aluminum (Al) causes a delayed suppression of nucleotide excision repair (NER) capacity in zebrafish (Danio rerio) embryos via disturbance of DNA lesion detection. Ecotoxicology and environmental safety. 242:113902
Chien, L.C., Wu, Y.H., Ho, T.N., Huang, Y.Y., Hsu, T. (2019) Heat stress modulates nucleotide excision repair capacity in zebrafish (Danio rerio) early and mid-early embryos via distinct mechanisms. Chemosphere. 238:124653
Ho, T.N., Paul, G.V., Chen, Y.H., Hsu, T. (2018) Heat stress upregulates G-T mismatch binding activities in zebrafish (Danio rerio) embryos preexposed and nonexposed to a sublethal level of cadmium (Cd). Chemosphere. 218:179-188
Chang, Y., Lee, W.Y., Lin, Y.J., Hsu, T. (2017) Mercury (II) impairs nucleotide excision repair (NER) in zebrafish (Danio rerio) embryos by targeting primarily at the stage of DNA incision. Aquatic toxicology (Amsterdam, Netherlands). 192:97-104
Ling, L.B., Chang, Y., Liu, C.W., Lai, P.L., Hsu, T. (2017) Oxidative stress intensity-related effects of cadmium (Cd) and paraquat (PQ) on UV-damaged-DNA binding and excision repair activities in zebrafish (Danio rerio) embryos. Chemosphere. 167:10-18
Ho, T.N., Sung, S.T., Huang, K.M., Hsu, T. (2015) Comparative Effects of Mercury(II) and Cadmium on MutS Homolog 6(MSH6)-Mediated DNA Mismatch Binding Activities in Zebrafish (Danio rerio) Embryos. Journal of biochemical and molecular toxicology. 29(11):513-20
Hsu, T., Huang, K.M., Tsai, H.T., Sung, S.T., and Ho, T.N. (2013) Cadmium(Cd)-induced oxidative stress down-regulates the gene expression of DNA mismatch recognition proteins MutS homolog 2 (MSH2) and MSH6 in zebrafish (Danio rerio) embryos. Aquatic toxicology (Amsterdam, Netherlands). 126C:9-16
Lai, Y.S., Hsieh, F.J., and Hsu, T. (2012) Affinity isolation and mass spectral analysis of 1,10-phenanthroline (OP)-stimulated UV-damaged-DNA binding proteins expressed in zebrafish (Danio rerio) embryos. Fish physiology and biochemistry. 38(4):1117-1129
Hsu, T. (2012) Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms. Oncogene. 31(18):2247-2257
Hsu, T., Tsai, H.T., Huang, K.M., Luan, M.C., and Hsieh, C.R. (2010) Sublethal levels of cadmium down-regulate the gene expression of DNA mismatch recognition protein MutS homolog 6 (MSH6) in zebrafish (Danio rerio) embryos. Chemosphere. 81(6):748-754
Hsu, L.Y., Yeh, F.L., Cheng, T.Y., Chang, Y.H., Liu, S.M., and Hsu, T. (2010) A spontaneous high expression of heat shock cognate 70 (HSC 70) in zebrafish Danio rerio larvae arising from tissue-specific translation of preexisting mRNA. Fisheries science : FS. 76:857-864
Yeh, F.L., Hsu, L.Y., Lin, B.A., Chen, C.F., Li, I.C., Tsai, S.H., and Hsu, T. (2006) Cloning of zebrafish (Danio rerio) heat shock factor 2 (HSF2) and similar patterns of HSF2 and HSF1 mRNA expression in brain tissues. Biochimie. 88(12):1983-1988
Lai, Y.S., Chiue, L.F., and Hsu, T. (2006) Low-molecular-weight vitellogenin 1-like proteins are components of a UV-damaged-DNA binding activity highly expressed in zebrafish (Danio rerio) embryos. Journal of experimental zoology. Part A, Ecological genetics and physiology. 305(3):215-224
Yeh, F.L., Wang, S.Y., Hsu, L.Y., Wang, D.Y., and Hsu, T. (2004) Cloning of the mismatch recognition protein MSH2 from zebrafish (Danio rerio) and its developmental stage-dependent mRNA expression. BBA Gene Structure and Expression. 1680(2):129-136
Yeh, F.-L., Yan, H.-L., Wang, S.-Y., Jung, T.-Y., and Hsu, T. (2003) Molecular cloning of zebrafish (Danio rerio) MutS homolog 6(MSH6) and noncoordinate expression of MSH6 gene activity and G-T mismatch binding proteins in zebrafish larvae. The Journal of experimental zoology. 297A(2):118-129
Hsu, T., Cheng, C.S., Shih, C.Y., and Yeh, F.L. (2002) Detection and partial characterization of a UV-damaged-DNA binding activity highly expressed in zebrafish (Danio rerio) embryos. Fish physiology and biochemistry. 25(1):41-51

NON-ZEBRAFISH PUBLICATIONS
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.