ZFIN Person: Etard, Christelle

ZFIN ID: ZDB-PERS-020724-7

ZFIN ID: ZDB-PERS-020724-7

Etard, Christelle

Email:	christelle.etard@itg.fzk.de
URL:
Affiliation:
Address:	Institute of Toxicology and Genetics Forschungszentrum Karlsruhe Postfach 3640 Karlsruhe, D-76021 Germany
Country:	Germany
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Characterisation of motility mutants in the zebrafish.

PUBLICATIONS

Masek, M., Etard, C., Hofmann, C., Hülsmeier, A.J., Zang, J., Takamiya, M., Gesemann, M., Neuhauss, S.C.F., Hornemann, T., Strähle, U., Bachmann-Gagescu, R. (2022) Loss of the Bardet-Biedl protein Bbs1 alters photoreceptor outer segment protein and lipid composition. Nature communications. 13:1282

Kröll-Hermi, A., Ebstein, F., Stoetzel, C., Geoffroy, V., Schaefer, E., Scheidecker, S., Bär, S., Takamiya, M., Kawakami, K., Zieba, B.A., Studer, F., Pelletier, V., Eyermann, C., Speeg-Schatz, C., Laugel, V., Lipsker, D., Sandron, F., McGinn, S., Boland, A., Deleuze, J.F., Kuhn, L., Chicher, J., Hammann, P., Friant, S., Etard, C., Krüger, E., Muller, J., Strähle, U., Dollfus, H. (2020) Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress. EMBO Molecular Medicine. 12(7):e11861

Estrada-Cuzcano, A., Etard, C., Delvallée, C., Stoetzel, C., Schaefer, E., Scheidecker, S., Geoffroy, V., Schneider, A., Studer, F., Mattioli, F., Chennen, K., Sigaudy, S., Plassard, D., Poch, O., Piton, A., Strahle, U., Muller, J., Dollfus, H. (2019) Novel IQCE variations confirm its role in postaxial polydactyly and cause ciliary defect phenotype in zebrafish. Human Mutation. 41(1):240-254

Joshi, S., Virdi, S., Etard, C., Geisler, R., Strähle, U. (2018) Mutation of a serine near the catalytic site of the choline acetyltransferase a gene almost completely abolishes motility of the zebrafish embryo. PLoS One. 13:e0207747

Paone, C., Rudeck, S., Etard, C., Strähle, U., Rottbauer, W., Just, S. (2018) Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response. Biochemical and Biophysical Research Communications. 496(2):339-345

Etard, C., Joshi, S., Stegmaier, J., Mikut, R., Strähle, U. (2017) Tracking of Indels by DEcomposition is a Simple and Effective Method to Assess Efficiency of Guide RNAs in Zebrafish. Zebrafish. 14(6):586-588

Stoetzel, C., Bär, S., De Craene, J.O., Scheidecker, S., Etard, C., Chicher, J., Reck, J.R., Perrault, I., Geoffroy, V., Chennen, K., Strähle, U., Hammann, P., Friant, S., Dollfus, H. (2016) A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi. Nature communications. 7:13586

Rudeck, S., Etard, C., Khan, M.M., Rottbauer, W., Rudolf, R., Strähle, U., Just, S. (2016) A compact unc45b-promoter drives muscle-specific expression in zebrafish and mouse. Genesis (New York, N.Y. : 2000). 54(8):431-8

Armant, O., Gourain, V., Etard, C., Strähle, U. (2016) Whole transcriptome data analysis of zebrafish mutants affecting muscle development. Data in brief. 8:61-8

Takamiya, M., Xu, F., Suhonen, H., Gourain, V., Yang, L., Ho, N.Y., Helfen, L., Schröck, A., Etard, C., Grabher, C., Rastegar, S., Schlunck, G., Reinhard, T., Baumbach, T., Strähle, U. (2016) Melanosomes in pigmented epithelia maintain eye lens transparency during zebrafish embryonic development. Scientific Reports. 6:25046

Etard, C., Armant, O., Roostalu, U., Gourain, V., Ferg, M., Strähle, U. (2015) Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells. Genome biology. 16:267

Scheidecker, S., Etard, C., Haren, L., Stoetzel, C., Hull, S., Arno, G., Plagnol, V., Drunat, S., Passemard, S., Toutain, A., Obringer, C., Koob, M., Geoffroy, V., Marion, V., Strähle, U., Ostergaard, P., Verloes, A., Merdes, A., Moore, A.T., Dollfus, H. (2015) Mutations in TUBGCP4 Alter Microtubule Organization via the γ-Tubulin Ring Complex in Autosomal-Recessive Microcephaly with Chorioretinopathy. American journal of human genetics. 96(4):666-74

Tixier, V., Bataillé, L., Etard, C., Jagla, T., Weger, M., Daponte, J.P., Strähle, U., Dickmeis, T., and Jagla, K. (2013) Glycolysis supports embryonic muscle growth by promoting myoblast fusion. Proceedings of the National Academy of Sciences of the United States of America. 110(47):18982-7

Bloch-Zupan, A., Jamet, X., Etard, C., Laugel, V., Muller, J., Geoffroy, V., Strauss, J.P., Pelletier, V., Marion, V., Poch, O., Strahle, U., Stoetzel, C., and Dollfus, H. (2011) Homozygosity Mapping and Candidate Prioritization Identify Mutations, Missed by Whole-Exome Sequencing, in SMOC2, Causing Major Dental Developmental Defects. American journal of human genetics. 89(6):773-781

Just, S., Meder, B., Berger, I.M., Etard, C., Trano, N., Patzel, E., Hassel, D., Marquart, S., Dahme, T., Vogel, B., Fishman, M.C., Katus, H.A., Strähle, U., and Rottbauer, W. (2011) The myosin-interacting protein SMYD1 is essential for sarcomere organization. Journal of Cell Science. 124(Pt 18):3127-36

Etard, C., Roostalu, U., and Strähle, U. (2010) Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos. The Journal of cell biology. 189(3):527-539

Etard, C., Roostalu, U., and Strähle, U. (2008) Shuttling of the chaperones Unc45b and Hsp90a between the A band and the Z line of the myofibril. The Journal of cell biology. 180(6):1163-1175

Hawkins, T.A., Haramis, A.P., Etard, C., Prodromou, C., Vaughan, C.K., Ashworth, R., Ray, S., Behra, M., Holder, N., Talbot, W.S., Pearl, L.H., Strähle, U., and Wilson, S.W. (2008) The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis. Development (Cambridge, England). 135(6):1147-1156

Etard, C., Behra, M., Fischer, N., Hutcheson, D., Geisler, R., and Strähle, U. (2007) The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis. Developmental Biology. 308(1):133-143

Etard, C., Behra, M., Ertzer, R., Fischer, N., Jesuthasan, S., Blader, P., Geisler, R., and Strähle, U. (2005) Mutation in the delta-subunit of the nAChR suppresses the muscle defects caused by lack of Dystrophin. Developmental Dynamics : an official publication of the American Association of Anatomists. 234(4):1016-1025

Behra, M., Etard, C., Cousin, X., and Strähle, U. (2004) The use of zebrafish mutants to identify secondary target effects of acetylcholine esterase inhibitors. Toxicological sciences : an official journal of the Society of Toxicology. 77(2):325-333

NON-ZEBRAFISH PUBLICATIONS
Etard, C., Gradl, D., Kunz, M., Eilers, M., and Wedlich, D. (2005) Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1. Mech. Dev. 122(4):545-56. PMID: 15804567

Etard, C., Wedlich, D., Bauer, A., Huber, O., and Kuhl, M. (2000) Expression of Xenopus homologs of the beta-catenin binding protein pontin52. Mech Dev. 94(1-2):219-22. PMID: 10842076