ZFIN Person: Lessman, Charles

ZFIN ID: ZDB-PERS-020717-9

ZFIN ID: ZDB-PERS-020717-9

Lessman, Charles

Email:	clessman@memphis.edu
URL:	http://umpeople.memphis.edu/clessman
Affiliation:
Address:	Department of Biology The University of Memphis 201 Life Sciences Building 3774 Walker Memphis, TN 38152 USA
Country:
Phone:	(901) 678-2963
Fax:	(901) 678-4457
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Our lab is interested in zebrafish oocyte maturation, oogenesis and developing screening tools to automate mutagenesis screens. Currently we have developed a new technique to analyze in vitro oocyte maturation (Computer-Aided Meiotic Maturation Assay or CAMMA). This procedure allows investigators to follow oocyte maturation in large arrays of oocytes with multiple treatment protocols.

PUBLICATIONS

Lessman, C.A., Brantley, N.A. (2020) Puberty visualized: sexual maturation in the transparent Casper zebrafish. Zygote (Cambridge, England). 28(4):322-332

Brantley, N., Lessman, C.A. (2019) In vivo assessment of gonad status, secondary sex characteristics and spawning in transparent Casper zebrafish. Mechanisms of Development. 160:103582

Eden, C.J., Ju, B., Murugesan, M., Phoenix, T.N., Nimmervoll, B., Tong, Y., Ellison, D.W., Finkelstein, D., Wright, K., Boulos, N., Dapper, J., Thiruvenkatam, R., Lessman, C.A., Taylor, M.R., Gilbertson, R.J. (2015) Orthotopic models of pediatric brain tumors in zebrafish. Oncogene. 34(13):1736-42

Lessman, C.A. (2012) Centrosomes in the zebrafish (Danio rerio): a review including the related basal body. Cilia. 1(1):9

Lessman, C.A. (2011) The developing zebrafish (Danio rerio): A vertebrate model for high-throughput screening of chemical libraries. Birth defects research. Part C, Embryo today : reviews. 93(3):268-280

Lessman, C.A., Taylor, M.R., Orisme, W., and Carver, E.A. (2010) Chapter 12 - Use of Flatbed Transparency Scanners in Zebrafish Research Versatile and Economical Adjuncts to Traditional Imaging Tools for the Danio rerio Laboratory. Methods in cell biology. 100:295-322

Lessman, C.A. (2009) Oocyte maturation: Converting the zebrafish oocyte to the fertilizable egg. General and comparative endocrinology. 161(1):53-57

Liu, J., and Lessman, C.A. (2008) Changes of gamma-tubulin expression and distribution in the zebrafish (Danio rerio) ovary, oocyte and embryo. Gene expression patterns : GEP. 8(4):237-247

Liu, J., and Lessman, C.A. (2007) Soluble tubulin complexes, gamma-tubulin, and their changing distribution in the zebrafish (Danio rerio) ovary, oocyte and embryo. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 147(1):56-73

Lessman, C.A., Nathani, R., Uddin, R., Walker, J., and Liu, J. (2007) Computer-aided meiotic maturation assay (CAMMA) of zebrafish (danio rerio) oocytes in vitro. Molecular reproduction and development. 74(1):97-107

Lessman, C.A. (2004) Computer-aided screening for zebrafish embryonic motility mutants. The Zebrafish: Cellular and Developmental Biology,2nd Ed. Methods Cell Biol.. 76:285-313

Lessman, C.A. (2002) Use of computer-aided screening for detection of motility mutants in zebrafish embryos. Real Time Imaging. 8(3):189-201

Liu, J.X. and Lessman, C.A. (2001) Changes in soluble and polymer alpha-tubulin pools during zebrafish oogenesis and embryogenesis. Molecular biology of the cell. (Suppl.) 12:2364

NON-ZEBRAFISH PUBLICATIONS