ZFIN Person: Holbech, Henrik

ZFIN ID: ZDB-PERS-011010-1

Holbech, Henrik

Email:	hol@biology.sdu.dk
URL:
Affiliation:	Environmental Endocrine Disruption Research Group
Address:	Danish Centre for Environmental Oestrogen Research Institute of Biology, University of Southern Denmark Odense University Campusvej 55 Odense M., DK-5230 Denmark
Country:	Denmark
Phone:	45-6550-2770
Fax:	45-6593-0457
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Volz, S.N., Poulsen, R., Hansen, M., Holbech, H. (2023) Bisphenol A alters retinal morphology, visually guided behavior, and thyroid hormone levels in zebrafish larvae. Chemosphere. 348:140776

Baumann, L., Holbech, H., Schmidt-Posthaus, H., Moissl, A.P., Hennies, M., Tiedemann, J., Weltje, L., Segner, H., Braunbeck, T. (2019) Does hepatotoxicity interfere with endocrine activity in zebrafish (Danio rerio)?. Chemosphere. 238:124589

Bjerregaard, P., Kinnberg, K.L., Mose, M.P., Holbech, H. (2018) Investigation of the potential endocrine effect of nitrate in zebrafish Danio rerio and brown trout Salmo trutta. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 211:32-40

Morthorst, J.E., Lund, B.F., Holbech, H., Bjerregaard, P. (2017) Two common mild analgesics have no effect on general endocrine mediated endpoints in zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 204:63-70

Örn, S., Holbech, H., Norrgren, L. (2016) Sexual disruption in zebrafish (Danio rerio) exposed to mixtures of 17α-ethinylestradiol and 17β-trenbolone. Environmental Toxicology and Pharmacology. 41:225-231

Kinnberg, K.L., Petersen, G.I., Albrektsen, M., Minghlani, M., Awad, S.M., Holbech, B.F., Green, J.W., Bjerregaard, P., Holbech, H. (2015) Endocrine-disrupting effect of the ultraviolet filter benzophenone-3 in zebrafish, Danio rerio. Environmental toxicology and chemistry. 34(12):2833-40

Baumann, L., Knörr, S., Keiter, S., Nagel, T., Rehberger, K., Volz, S., Oberrauch, S., Schiller, V., Fenske, M., Holbech, H., Segner, H., Braunbeck, T. (2014) Persistence of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the androgen 17β-trenbolone. Environmental toxicology and chemistry. 33(11):2488-96

Baumann, L., Knörr, S., Keiter, S., Rehberger, K., Volz, S., Schiller, V., Fenske, M., Holbech, H., Segner, H., Braunbeck, T. (2014) Reversibility of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the estrogen 17α-ethinylestradiol. Toxicology and applied pharmacology. 278(3):230-7

Holbech, H., Schröder, K.D., Nielsen, M.L., Brande-Lavridsen, N., Holbech, B.F., and Bjerregaard, P. (2013) Estrogenic effect of the phytoestrogen biochanin A in zebrafish, Danio rerio, and brown trout, Salmo trutta. Aquatic toxicology (Amsterdam, Netherlands). 144-145C:19-25

Baumann, L., Holbech, H., Keiter, S., Kinnberg, K.L., Knörr, S., Nagel, T., and Braunbeck, T. (2013) The maturity index as a tool to facilitate the interpretation of changes in vitellogenin production and sex ratio in the Fish Sexual Development Test. Aquatic toxicology (Amsterdam, Netherlands). 128-129C:34-42

Keiter, S., Baumann, L., Färber, H., Holbech, H., Skutlarek, D., and Engwall, M., and Braunbeck, T. (2012) Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 118-119C:116-129

Holbech, H., Kinnberg, K., Brande-Lavridsen, N., Bjerregaard, P., Petersen, G.I., Norrgren, L., Orn, S., Braunbeck, T., Baumann, L., Bomke, C., Dorgerloh, M., Bruns, E., Ruehl-Fehlert, C., Green, J.W., Springer, T.A., and Gourmelon, A. (2012) Comparison of zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) as test species in the Fish Sexual Development Test (FSDT). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 155(2):407-15

Haldén, A.N., Nyholm, J.R., Andersson, P.L., Holbech, H., and Norrgren, L. (2010) Oral exposure of adult zebrafish (Danio rerio) to 2,4,6-tribromophenol affects reproduction. Aquatic toxicology (Amsterdam, Netherlands). 100(1):30-37

Morthorst, J.E., Holbech, H., and Bjerregaard, P. (2010) Trenbolone causes irreversible masculinization of zebrafish at environmentally relevant concentrations. Aquatic toxicology (Amsterdam, Netherlands). 98(4):336-343

Holth, T.F., Nourizadeh-Lillabadi, R., Blaesbjerg, M., Grung, M., Holbech, H., Petersen, G.I., Aleström, P., and Hylland, K. (2008) Differential gene expression and biomarkers in zebrafish (Danio rerio) following exposure to produced water components. Aquatic toxicology (Amsterdam, Netherlands). 90(4):277-291

Kinnberg, K., Holbech, H., Petersen, G.I., and Bjerregaard, P. (2007) Effects of the fungicide prochloraz on the sexual development of zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 145(2):165-170

Orn, S., Svenson, A., Viktor, T., Holbech, H., and Norrgren, L. (2006) Male-Biased Sex Ratios and Vitellogenin Induction in Zebrafish Exposed to Effluent Water from a Swedish Pulp Mill. Archives of environmental contamination and toxicology. 51(3):445-451

Holbech, H., Kinnberg, K., Petersen, G.I., Jackson, P., Hylland, K., Norrgren, L., and Bjerregaard, P. (2006) Detection of endocrine disrupters: Evaluation of a Fish Sexual Development Test (FSDT). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 144(1):57-66

Andersen, L., Kinnberg, K., Holbech, H., Korsgaard, B. and Bjerregaard, P. (2004) Evaluation of a 40 day Assay for Testing Endocrine Disrupters: Effects of an Anti-Estrogen and an Aromatase Inhibitor on Sex Ratio and Vitellogenin Concentrations in Juvenile Zebrafish (Danio rerio). Fish physiology and biochemistry. 30(3-4):257-266

Orn, S., Holbech, H., Madsen, T.H., Norrgren, L., and Petersen, G.I. (2003) Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone. Aquatic toxicology (Amsterdam, Netherlands). 65(4):397-411

van der Ven, L.T.M., Holbech, H., Fenske, M., van den Brandhof, E.J., Gielis-Proper, F.K., and Wester, P.W. (2003) Vitellogenin expression in zebrafish Danio rerio: evaluation by histochemistry, immunohistochemistry, and in situ mRNA hybridisation. Aquatic toxicology (Amsterdam, Netherlands). 65(1):1-11

Andersen, L., Holbech, H., Gessbo, A., Norrgren, L., and Petersen, G.I. (2003) Effects of exposure to 17alpha-ethinylestradiol during early development on sexual differentiation and induction of vitellogenin in zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 134(3):365-374

Rose, J., Holbech, H., Lindholst, C., Narum, U., Povlsen, A., Korsgaard, B., and Bjerregaard, P. (2002) Vitellogenin induction by 17beta-estradiol and 17alpha-ethinylestradiol in male zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 131(4):531-539

Andersen, L., Petersen, G.I., Gessbo, A., Oern, S., Holbech, H., Bjerregaard, P., and Norrgren, L. (2001) Zebrafish Danio rerio and roach Rutilus rutilus: Two species suitable for evaluating effects of endocrine disrupting chemicals?. Aquatic ecosystem health & management. 4(3):275-282

Holbech, H., Andersen, L., Petersen, G.I., Korsgaard, B., Pedersen, K.L., and Bjerregaard, P. (2001) Development of an ELISA for vitellogenin in whole body homogenate of zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 130(1):119-131

NON-ZEBRAFISH PUBLICATIONS