ZFIN ID: ZDB-PERS-001129-6
Schorpp, Michael
Email: schorpp@immunbio.mpg.de
URL:
Affiliation: Boehm Lab
Address: Department of Developmental Immunology Max-Planck-Institute for Immunobiology Stuebeweg 51 Freiburg, D-79108 Germany
Country: Germany
Phone: 49-761-510-8328
Fax: 49-761-510-8323
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Lawir, D.F., Soza-Ried, C., Iwanami, N., Siamishi, I., Bylund, G.O., O Meara, C., Sikora, K., Kanzler, B., Johansson, E., Schorpp, M., Cauchy, P., Boehm, T. (2024) Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish. Communications biology. 7:3131
Schorpp, M., Swann, J.B., Hess, I., Ho, H.C., Pietsch, T.W., Boehm, T. (2023) Foxn1 is not essential for T-cell development in teleosts. European journal of immunology. 53(12):e2350725
Hess, I., Sagar, ., O Meara, C., Grün, D., Schorpp, M., Boehm, T. (2022) Stage-specific and cell type-specific requirements of ikzf1 during haematopoietic differentiation in zebrafish. Scientific Reports. 12:2140121401
O'Meara, C.P., Guerri, L., Lawir, D.F., Mateos, F., Iconomou, M., Iwanami, N., Soza-Ried, C., Sikora, K., Siamishi, I., Giorgetti, O., Peter, S., Schorpp, M., Boehm, T. (2021) Genetic landscape of T cells identifies synthetic lethality for T-ALL. Communications biology. 4:1201
Iwanami, N., Lawir, D.F., Sikora, K., O Meara, C., Takeshita, K., Schorpp, M., Boehm, T. (2020) Transgenerational inheritance of impaired larval T cell development in zebrafish. Nature communications. 11:4505
Lawir, D.F., Sikora, K., O'Meara, C.P., Schorpp, M., Boehm, T. (2020) Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development. Proceedings of the National Academy of Sciences of the United States of America. 117(27):15799-15808
Iwanami, N., Takeshita, K., Lawir, D.F., Suetake, I., Tajima, S., Sikora, K., Trancoso, I., ÓMeara, C., Siamishi, I., Takahama, Y., Furutani-Seiki, M., Kondoh, H., Yonezawa, Y., Schorpp, M., Boehm, T. (2020) Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience. 23:101260
Lawir, D.F., Hess, I., Sikora, K., Iwanami, N., Siamishi, I., Schorpp, M., Boehm, T. (2019) Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. Proceedings of the National Academy of Sciences of the United States of America. 116(52):26759-26767
Lawir, D.F., Iwanami, N., Schorpp, M., Boehm, T. (2017) A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish. Scientific Reports. 7:44145
Iwanami, N., Hess, I., Schorpp, M., Boehm, T. (2017) Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells. Methods in cell biology. 138:151-161
Iwanami, N., Sikora, K., Richter, A.S., Mönnich, M., Guerri, L., Soza-Ried, C., Lawir, D.F., Mateos, F., Hess, I., O'Meara, C.P., Schorpp, M., Boehm, T. (2016) Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Cell Reports. 17:2259-2270
Swann, J.B., Weyn, A., Nagakubo, D., Bleul, C.C., Toyoda, A., Happe, C., Netuschil, N., Hess, I., Haas-Assenbaum, A., Taniguchi, Y., Schorpp, M., Boehm, T. (2014) Conversion of the thymus into a bipotent lymphoid organ by replacement of FOXN1 with its paralog, FOXN4. Cell Reports. 8:1184-97
Hess, I., Iwanami, N., Schorpp, M., and Boehm, T. (2013) Zebrafish model for allogeneic hematopoietic cell transplantation not requiring preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 110(11):4327-32
Iwanami, N., Mateos, F., Hess, I., Riffel, N., Soza-Ried, C., Schorpp, M., and Boehm, T. (2011) Genetic Evidence for an Evolutionarily Conserved Role of IL-7 Signaling in T Cell Development of Zebrafish. Journal of immunology (Baltimore, Md. : 1950). 186(12):7060-6
Soza-Ried, C., Hess, I., Netuschil, N., Schorpp, M., and Boehm, T. (2010) Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved. Proceedings of the National Academy of Sciences of the United States of America. 107(40):17304-17308
Mönnich, M., Hess, I., Wiest, W., Bachrati, C., Hickson, I.D., Schorpp, M., and Boehm, T. (2010) Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha. European journal of immunology. 40(9):2379-2384
Bajoghli, B., Aghaallaei, N., Hess, I., Rode, I., Netuschil, N., Tay, B.H., Venkatesh, B., Yu, J.K., Kaltenbach, S.L., Holland, N.D., Diekhoff, D., Happe, C., Schorpp, M., and Boehm, T. (2009) Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates. Cell. 138(1):186-197
Soza-Ried, C., Bleul, C.C., Schorpp, M., and Boehm, T. (2008) Maintenance of thymic epithelial phenotype requires extrinsic signals in mouse and zebrafish. Journal of immunology (Baltimore, Md. : 1950). 181(8):5272-5277
Schorpp, M., Bialecki, M., Diekhoff, D., Walderich, B., Odenthal, J., Maischein, H.M., Zapata, A.G., and Boehm, T. (2006) Conserved functions of ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish. Journal of immunology (Baltimore, Md. : 1950). 177(4):2463-2476
Boehm, T., Bleul, C.C., and Schorpp, M. (2003) Genetic dissection of thymus development in mouse and zebrafish. Immunological reviews. 195:15-27
Schorpp, M., Leicht, M., Nold, E., Hammerschmidt, M., Haas-Assenbaum, A., Wiest, W., and Boehm, T. (2002) A zebrafish orthologue (whnb) of the mouse nude gene is expressed in the epithelial compartment of the embryonic thymic rudiment. Mechanisms of Development. 118(1-2):179-185
Schlake, T., Schorpp, M., and Boehm, T. (2000) Formation of regulator/target gene relationships during evolution. Gene. 256(1-2):29-34
Schlake, T., Schorpp, M., Nehls, M., and Boehm, T. (1997) The nude gene encodes a sequence-specific DNA binding protein with homologs in organisms that lack an anticipatory immune system. Proceedings of the National Academy of Sciences of the United States of America. 94(8):3842-3847

NON-ZEBRAFISH PUBLICATIONS