Morpholino
MO3-eaf2
- ID
- ZDB-MRPHLNO-130501-9
- Name
- MO3-eaf2
- Previous Names
- None
- Target
- Sequence
-
5' - AAAAGATGCAACTTACATCGTACCG - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
Splice-blocking MO.
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-eaf2
No data available
Phenotype
Phenotype resulting from MO3-eaf2
| Phenotype | Fish | Figures |
|---|---|---|
| neuroectoderm anterior region decreased size, abnormal | WT + MO3-eaf2 |
Fig. 1 
from Liu et al., 2013 |
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Phenotype of all Fish created by or utilizing MO3-eaf2
| Phenotype | Fish | Conditions | Figures |
|---|---|---|---|
| neuroectoderm anterior region decreased size, abnormal | WT + MO3-eaf2 | standard conditions |
Fig. 1
from Liu et al., 2013 |
1 - 1 of 1
Citations
- Liu, W., Lin, S., Li, L., Tai, Z., Liu, J.X. (2023) Zebrafish ELL-associated factors Eaf1/2 modulate erythropoiesis via regulating gata1a expression and WNT signaling to facilitate hypoxia tolerance. Cell regeneration (London, England). 12:1010
- Liu, J.X., Xu, Q.H., Yu, X., Zhang, T., Xie, X., Ouyang, G. (2018) Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/β-Catenin activity.. International journal of biological sciences. 14:705-716
- Liu, J.X., Xu, Q.H., Li, S., Yu, X., Liu, W., Ouyang, G., Zhang, T., Chen, L.L. (2017) Transcriptional factors Eaf1/2 inhibit endoderm and mesoderm formation via suppressing TGF-β signaling. Biochimica et biophysica acta. 1860(10):1103-1116
- Liu, J.X., Zhang, D., Xie, X., Ouyang, G., Liu, X., Sun, Y., and Xiao, W. (2013) Eaf1 and Eaf2 negatively regulate canonical Wnt/β-catenin signaling. Development (Cambridge, England). 140(5):1067-1078
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