Morpholino

MO1-scn12aa

ID
ZDB-MRPHLNO-100616-1
Name
MO1-scn12aa
Previous Names
  • AA-MO1 (1)
Target
Sequence
5' - CCGCTGGTAAGAGCATGGTCGCCAT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-scn12aa
Expressed Gene Anatomy Figures
gata4 Fig. 4 from Chopra et al., 2010
gata5 Fig. 4 from Chopra et al., 2010
hand2 Fig. 4 from Chopra et al., 2010
myh7 Fig. 5 from Chopra et al., 2010
myl7 Fig. 5 from Chopra et al., 2010
nkx2.5 Fig. 4,  Fig. 5 from Chopra et al., 2010
Phenotype
Phenotype resulting from MO1-scn12aa
Phenotype Fish Figures
atrium decreased size, abnormal f1Tg + MO1-scn12aa Fig. 3 from Chopra et al., 2010
atrium morphology, abnormal f1Tg + MO1-scn12aa Fig. 2 from Chopra et al., 2010
atrium orientation cardiac ventricle, abnormal f1Tg + MO1-scn12aa Fig. 2,  Fig. 3,  Fig. S6 from Chopra et al., 2010
blood circulation disrupted, abnormal f1Tg + MO1-scn12aa Fig. 2 from Chopra et al., 2010
cardiac muscle cell differentiation disrupted, abnormal WT + MO1-scn12aa Fig. 5 from Chopra et al., 2010
cardiac ventricle decreased size, abnormal f1Tg + MO1-scn12aa Fig. 3 from Chopra et al., 2010
cardiac ventricle lacks all parts of type trabecular layer of ventricle, abnormal f1Tg + MO1-scn12aa Fig. 3 from Chopra et al., 2010
cardiac ventricle morphology, abnormal f1Tg + MO1-scn12aa Fig. 2 from Chopra et al., 2010
cardiac ventricle cardiac muscle cell irregular spatial pattern, abnormal f1Tg + MO1-scn12aa Fig. 3 from Chopra et al., 2010
eye apoptotic, abnormal WT + MO1-scn12aa Fig. S7 from Chopra et al., 2010
forebrain apoptotic, abnormal WT + MO1-scn12aa Fig. S7 from Chopra et al., 2010
head decreased size, abnormal WT + MO1-scn12aa Fig. 2,  Fig. S6 from Chopra et al., 2010
heart has fewer parts of type cardiac muscle cell, abnormal f2Tg + MO1-scn12aa Fig. 3 from Chopra et al., 2010
heart hypoplastic, abnormal WT + MO1-scn12aa Fig. S7 from Chopra et al., 2010
heart malformed, abnormal WT + MO1-scn12aa Fig. S7 from Chopra et al., 2010
heart contraction decreased rate, abnormal f1Tg + MO1-scn12aa Fig. 2 from Chopra et al., 2010
heart looping arrested, abnormal WT + MO1-scn12aa Fig. 2,  Fig. 3,  Fig. S6 from Chopra et al., 2010
heart primordium decreased size, abnormal WT + MO1-scn12aa Fig. 5 from Chopra et al., 2010
heart primordium has fewer parts of type cardiac muscle cell, abnormal WT + MO1-scn12aa Fig. 5 from Chopra et al., 2010
heart rudiment decreased size, abnormal f1Tg + MO1-scn12aa Fig. 5 from Chopra et al., 2010
heart rudiment has fewer parts of type cardiac muscle cell, abnormal f1Tg + MO1-scn12aa Fig. 5 from Chopra et al., 2010
Phenotype of all Fish created by or utilizing MO1-scn12aa
Phenotype Fish Conditions Figures
forebrain apoptotic, abnormal WT + MO1-scn12aa standard conditions Fig. S7 from Chopra et al., 2010
head decreased size, abnormal WT + MO1-scn12aa standard conditions Fig. 2,  Fig. S6 from Chopra et al., 2010
atrium orientation cardiac ventricle, abnormal WT + MO1-scn12aa standard conditions Fig. S6 from Chopra et al., 2010
heart primordium has fewer parts of type cardiac muscle cell, abnormal WT + MO1-scn12aa standard conditions Fig. 5 from Chopra et al., 2010
heart looping arrested, abnormal WT + MO1-scn12aa standard conditions Fig. S6 from Chopra et al., 2010
cardiac muscle cell differentiation disrupted, abnormal WT + MO1-scn12aa standard conditions Fig. 5 from Chopra et al., 2010
heart hypoplastic, abnormal WT + MO1-scn12aa standard conditions Fig. S7 from Chopra et al., 2010
heart primordium decreased size, abnormal WT + MO1-scn12aa standard conditions Fig. 5 from Chopra et al., 2010
heart malformed, abnormal WT + MO1-scn12aa standard conditions Fig. S7 from Chopra et al., 2010
eye apoptotic, abnormal WT + MO1-scn12aa standard conditions Fig. S7 from Chopra et al., 2010
heart looping arrested, abnormal WT + MO1-scn12aa + MO4-tp53 standard conditions Fig. S6 from Chopra et al., 2010
atrium orientation cardiac ventricle, abnormal WT + MO1-scn12aa + MO4-tp53 standard conditions Fig. S6 from Chopra et al., 2010
heart contraction decreased rate, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 2 from Chopra et al., 2010
cardiac ventricle morphology, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 2 from Chopra et al., 2010
atrium decreased size, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 3 from Chopra et al., 2010
blood circulation disrupted, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 2 from Chopra et al., 2010
heart rudiment decreased size, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 5 from Chopra et al., 2010
cardiac muscle cell differentiation disrupted, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 5 from Chopra et al., 2010
atrium morphology, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 2 from Chopra et al., 2010
cardiac ventricle lacks all parts of type trabecular layer of ventricle, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 3 from Chopra et al., 2010
heart rudiment has fewer parts of type cardiac muscle cell, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 5 from Chopra et al., 2010
heart looping arrested, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 2,  Fig. 3 from Chopra et al., 2010
atrium orientation cardiac ventricle, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 2,  Fig. 3 from Chopra et al., 2010
cardiac ventricle cardiac muscle cell irregular spatial pattern, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 3 from Chopra et al., 2010
cardiac ventricle decreased size, abnormal f1Tg + MO1-scn12aa standard conditions Fig. 3 from Chopra et al., 2010
heart looping arrested, abnormal f2Tg + MO1-scn12aa standard conditions Fig. 3 from Chopra et al., 2010
heart has fewer parts of type cardiac muscle cell, abnormal f2Tg + MO1-scn12aa standard conditions Fig. 3 from Chopra et al., 2010
atrium orientation cardiac ventricle, abnormal f2Tg + MO1-scn12aa standard conditions Fig. 3 from Chopra et al., 2010
heart looping decreased process quality, abnormal WT + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
regulation of heart contraction disrupted, abnormal WT + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Chetaille et al., 2014
heart contraction decreased rate, abnormal WT + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Chetaille et al., 2014
heart edematous, abnormal WT + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
heart contraction decreased process quality, abnormal WT + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
head decreased size, abnormal WT + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
head decreased size, abnormal WT + MO1-scn12aa + MO2-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
heart looping arrested, abnormal f1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
blood circulation disrupted, abnormal f1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
atrium morphology, abnormal f1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
heart contraction decreased rate, abnormal f1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
atrium orientation cardiac ventricle, abnormal f1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
cardiac ventricle morphology, abnormal f1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
atrium orientation cardiac ventricle, abnormal f1Tg + MO1-scn12aa + MO2-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
cardiac ventricle morphology, abnormal f1Tg + MO1-scn12aa + MO2-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
heart looping arrested, abnormal f1Tg + MO1-scn12aa + MO2-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
atrium morphology, abnormal f1Tg + MO1-scn12aa + MO2-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
heart contraction decreased rate, abnormal f1Tg + MO1-scn12aa + MO2-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
blood circulation disrupted, abnormal f1Tg + MO1-scn12aa + MO2-scn5lab standard conditions Fig. 2 from Chopra et al., 2010
heart has fewer parts of type cardiac muscle cell, abnormal f2Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 3 from Chopra et al., 2010
heart looping decreased process quality, abnormal vcc1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
heart edematous, abnormal vcc1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
heart contraction decreased process quality, abnormal vcc1Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
heart looping decreased process quality, abnormal vcc2Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
heart edematous, abnormal vcc2Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
heart contraction decreased process quality, abnormal vcc2Tg + MO1-scn12aa + MO1-scn5lab standard conditions Fig. 4 from Huttner et al., 2013
Citations
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.