Morpholino

MO1-ednrab

ID

ZDB-MRPHLNO-070829-1

Name

MO1-ednrab

Previous Names

ednra1 MO (1)
MO1-ednra
MO1-ednraa

Target

ednrab (1)

Sequence

5' - AGTGGTGTGTTCACCTGTTTGAGGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

targets sixth transmembrane domain; splice blocker

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-ednrab

Expressed Gene	Anatomy	Figures
dlx2a	pharyngeal arch	Fig. 4 from Nair et al., 2007
edn1	ectoderm pharyngeal arch pharyngeal endoderm	Fig. 6 from Nair et al., 2007
en2a	mandibular muscle	Fig. 4 from Nair et al., 2007
gsc	dorsal hyoid arch palatoquadrate arch ventral hyoid arch	Fig. 4 from Nair et al., 2007
hand2	mandibular arch skeleton pharyngeal arch	Fig. 4 , Fig. 5 from Nair et al., 2007
nkx3-2	dorsal hyoid arch mandibular arch skeleton palatoquadrate arch ventral hyoid arch	Fig. 5 from Nair et al., 2007
sox9a	Meckel's cartilage palatoquadrate cartilage	Fig. 5 from Nair et al., 2007

Phenotype

Phenotype resulting from MO1-ednrab

Phenotype	Fish	Figures
hyosymplectic cartilage dorsal region fused with ceratohyal cartilage ventral region, abnormal	WT + MO1-ednrab	Fig. 3 from Nair et al., 2007
interhyal cartilage aplastic, abnormal	WT + MO1-ednrab	Fig. 3 from Nair et al., 2007
Meckel's cartilage fused with ceratohyal cartilage, abnormal	WT + MO1-ednrab	Fig. 3 from Nair et al., 2007
Meckel's cartilage ventral region fused with palatoquadrate cartilage dorsal region, abnormal	WT + MO1-ednrab	Fig. 3 from Nair et al., 2007
pharyngeal arch 1 decreased length, abnormal	WT + MO1-ednrab	Fig. 4 from Hisano et al., 2013
ventral mandibular arch decreased length, abnormal	WT + MO1-ednrab	Fig. 3 from Nair et al., 2007

Phenotype of all Fish created by or utilizing MO1-ednrab

Phenotype	Fish	Conditions	Figures
interhyal cartilage aplastic, abnormal	WT + MO1-ednrab	standard conditions	Fig. 3 from Nair et al., 2007
Meckel's cartilage ventral region fused with palatoquadrate cartilage dorsal region, abnormal	WT + MO1-ednrab	standard conditions	Fig. 3 from Nair et al., 2007
ventral mandibular arch decreased length, abnormal	WT + MO1-ednrab	standard conditions	Fig. 3 from Nair et al., 2007
pharyngeal arch 1 decreased length, abnormal	WT + MO1-ednrab	standard conditions	Fig. 4 from Hisano et al., 2013
hyosymplectic cartilage dorsal region fused with ceratohyal cartilage ventral region, abnormal	WT + MO1-ednrab	standard conditions	Fig. 3 from Nair et al., 2007
Meckel's cartilage fused with ceratohyal cartilage, abnormal	WT + MO1-ednrab	standard conditions	Fig. 3 from Nair et al., 2007
pharyngeal arch 1 decreased length, abnormal	fn1a^kt259/kt259 + MO1-ednrab	standard conditions	Fig. 4 from Hisano et al., 2013
ventral mandibular arch disorganized, abnormal	fn1a^kt259/kt259 + MO1-ednrab	standard conditions	Fig. 4 from Hisano et al., 2013
Meckel's cartilage decreased length, abnormal	WT + MO1-ednrab + MO2-ednraa	standard conditions	Fig. 5, Fig. S8 from Gordon et al., 2015
ceratohyal cartilage hypoplastic, abnormal	WT + MO1-ednrab + MO2-ednraa	standard conditions	Fig. S8 from Gordon et al., 2015
mandibular arch skeleton cartilage development disrupted, abnormal	WT + MO1-ednrab + MO2-ednraa	standard conditions	Fig. 5, Fig. S8 from Gordon et al., 2015
ceratohyal cartilage aplastic, abnormal	WT + MO1-ednrab + MO2-ednraa	standard conditions	Fig. 3 from Nair et al., 2007
Meckel's cartilage absent, abnormal	WT + MO1-ednrab + MO2-ednraa	standard conditions	Fig. 5 from Gordon et al., 2015
ventral mandibular arch aplastic, abnormal	WT + MO1-ednrab + MO2-ednraa	standard conditions	Fig. 3 from Nair et al., 2007
Meckel's cartilage decreased size, abnormal	WT + MO1-ednrab + MO2-ednraa	standard conditions	Fig. 3 from Nair et al., 2007
heart tube mislocalised laterally, abnormal	fn1a^kt259/kt259; ko07Tg + MO1-ednrab	standard conditions	Fig. 4 from Hisano et al., 2013
heart tube increased amount, abnormal	fn1a^kt259/kt259; ko07Tg + MO1-ednrab	standard conditions	Fig. 4 from Hisano et al., 2013

Citations