ZFIN Morpholino: MO4-ptf1a

Target Location

Genome Build: GRCz11Chromosome: 2

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO4-ptf1a

No data available

Phenotype

Phenotype resulting from MO4-ptf1a

No data available

Phenotype of all Fish created by or utilizing MO4-ptf1a

Phenotype	Fish	Conditions	Figures
amacrine cell absent, abnormal	ptf1a^sa126/sa126 + MO1-ptf1a + MO4-ptf1a + MO4-tp53	standard conditions	Fig. 2 from Randlett et al., 2013
retinal inner plexiform layer decreased thickness, abnormal	ptf1a^sa126/sa126 + MO1-ptf1a + MO4-ptf1a + MO4-tp53	standard conditions	Fig. 2 from Randlett et al., 2013
retinal outer plexiform layer ptf1a expression absent, abnormal	WT + MO1-ptf1a + MO4-ptf1a	control	Fig. 1 from Davison et al., 2021
retinal inner nuclear layer ptf1a expression absent, abnormal	WT + MO1-ptf1a + MO4-ptf1a	control	Fig. 1 from Davison et al., 2021
retinal inner plexiform layer ptf1a expression absent, abnormal	WT + MO1-ptf1a + MO4-ptf1a	control	Fig. 1 from Davison et al., 2021

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Citations

Include unpublished citations

Davison, C., Zolessi, F.R. (2021) Slit2 is necessary for optic axon organization in the zebrafish ventral midline. Cells & development. 166:203677
Rulands, S., Iglesias Gonzalez, A.B., Boije, H. (2018) Deterministic fate assignment of Müller glia cells in the zebrafish retina suggest a clonal backbone during development. The European journal of neuroscience. 48(12):3597-3605
Ng Chi Kei, J., Dudczig, S., Currie, P.D., Jusuf, P.R. (2016) Feedback from each retinal neuron population drives expression of subsequent fate determinant genes without influencing the cell cycle exit timing. The Journal of comparative neurology. 524(13):2553-66
Boije, H., Rulands, S., Dudczig, S., Simons, B.D., Harris, W.A. (2015) The Independent Probabilistic Firing of Transcription Factors: A Paradigm for Clonal Variability in the Zebrafish Retina. Developmental Cell. 34(5):532-43
Almeida, A.D., Boije, H., Chow, R.W., He, J., Tham, J., Suzuki, S.C., Harris, W.A. (2014) Spectrum of Fates: a new approach to the study of the developing zebrafish retina. Development (Cambridge, England). 141:1971-80
Weber, I.P., Ramos, A.P., Strzyz, P.J., Leung, L.C., Young, S., and Norden, C. (2014) Mitotic Position and Morphology of Committed Precursor Cells in the Zebrafish Retina. Cell Reports. 7(2):386-97
Randlett, O., MacDonald, R.B., Yoshimatsu, T., Almeida, A.D., Suzuki, S.C., Wong, R.O., Harris, W.A. (2013) Cellular requirements for building a retinal neuropil. Cell Reports. 3:282-90
Jusuf, P.R., Albadri, S., Paolini, A., Currie, P.D., Argenton, F., Higashijima, S., Harris, W.A., and Poggi, L. (2012) Biasing Amacrine Subtypes in the Atoh7 Lineage through Expression of Barhl2. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(40):13929-13944
Jusuf, P.R., Almeida, A.D., Randlett, O., Joubin, K., Poggi, L., and Harris, W.A. (2011) Origin and determination of inhibitory cell lineages in the vertebrate retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(7):2549-2562
Pisharath, H., Rhee, J.M., Swanson, M.A., Leach, S.D., and Parsons, M.J. (2007) Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase. Mechanisms of Development. 124(3):218-229

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