ZFIN Morpholino: MO1-foxc1a

Target Location

Genome Build: GRCz11Chromosome: 2

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-foxc1a

No data available

Phenotype

Phenotype resulting from MO1-foxc1a

Phenotype	Fish	Figures
pronephric podocyte decreased amount, abnormal	TU + MO1-foxc1a	Fig. 3 from O'Brien et al., 2011

1 - 1 of 1

Phenotype of all Fish created by or utilizing MO1-foxc1a

Phenotype	Fish	Conditions	Figures
pronephric podocyte decreased amount, abnormal	TU + MO1-foxc1a	standard conditions	Fig. 3 from O'Brien et al., 2011
optic fissure closure incomplete, abnormal	WT + MO1-foxc1a + MO2-foxc1a	standard conditions	Fig. 6 from Lupo et al., 2011
closure of optic fissure arrested, abnormal	WT + MO1-foxc1a + MO2-foxc1a	standard conditions	Fig. 6 from Lupo et al., 2011
endocardium decreased size, abnormal	WT + MO13-tp53 + MO1-foxc1a + MO3-foxc1a	standard conditions	Fig. S5 from Palencia-Desai et al., 2011
endocardium morphology, abnormal	WT + MO13-tp53 + MO1-foxc1a + MO3-foxc1a	standard conditions	Fig. S5 from Palencia-Desai et al., 2011

1 - 5 of 13 Show all

Citations

Include unpublished citations

Lupo, G., Gestri, G., O'Brien, M., Denton, R.M., Chandraratna, R.A., Ley, S.V., Harris, W.A., and Wilson, S.W. (2011) Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme. Proceedings of the National Academy of Sciences of the United States of America. 108(21):8698-8703
O'Brien, L.L., Grimaldi, M., Kostun, Z., Wingert, R.A., Selleck, R., and Davidson, A.J. (2011) Wt1a, Foxc1a, and the Notch mediator Rbpj physically interact and regulate the formation of podocytes in zebrafish. Developmental Biology. 358(2):318-30
Palencia-Desai, S., Kohli, V., Kang, J., Chi, N.C., Black, B.L., and Sumanas, S. (2011) Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. Development (Cambridge, England). 138(21):4721-4732
Lee, H.C., Tseng, W.A., Lo, F.Y., Liu, T.M., and Tsai, H.J. (2009) FoxD5 mediates anterior-posterior polarity through upstream modulator Fgf signaling during zebrafish somitogenesis. Developmental Biology. 336(2):232-245
Skarie, J.M., and Link, B.A. (2009) FoxC1 is essential for vascular basement membrane integrity and hyaloid vessel morphogenesis. Investigative ophthalmology & visual science. 50(11):5026-5034
Berry, F.B., Skarie, J.M., Mirzayans, F., Fortin, Y., Hudson, T.J., Raymond, V., Link, B.A., and Walter, M.A. (2008) FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A. Human molecular genetics. 17(4):490-505
Topczewska, J.M., Topczewski, J., Shostak, A., Kume, T., Solnica-Krezel, L., and Hogan, B.L. (2001) The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish. Genes & Development. 15(18):2483-2493

1 - 7 of 7

Show