ZFIN Morpholino: MO1-fgf8a

Target Location

Genome Build: GRCz11Chromosome: 13

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-fgf8a

No data available

Phenotype

Phenotype resulting from MO1-fgf8a

Phenotype	Fish	Figures
eye pax6a expression decreased amount, abnormal	AB + MO1-fgf8a	Fig. 2 from Zhang et al., 2017
forebrain pax6a expression decreased amount, abnormal	AB + MO1-fgf8a	Fig. 2 from Zhang et al., 2017
hindbrain pax6a expression decreased amount, abnormal	AB + MO1-fgf8a	Fig. 2 from Zhang et al., 2017
Kupffer's vesicle cilium decreased amount, abnormal	AB + MO1-fgf8a	Fig. 5 from Hong et al., 2009
midbrain pax6a expression mislocalised, abnormal	AB + MO1-fgf8a	Fig. 2 from Zhang et al., 2017

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Phenotype of all Fish created by or utilizing MO1-fgf8a

Phenotype	Fish	Conditions	Figures
midbrain posterior side otx2b expression increased distribution, abnormal	AB + MO1-fgf8a	standard conditions	Fig. 1 from Zhang et al., 2017
midbrain pax6a expression mislocalised, abnormal	AB + MO1-fgf8a	standard conditions	Fig. 2 from Zhang et al., 2017
midbrain posterior region en2b expression absent, abnormal	AB + MO1-fgf8a	standard conditions	Fig. 8 from Zhang et al., 2017
midbrain posterior region epha4a expression mislocalised, abnormal	AB + MO1-fgf8a	standard conditions	Fig. 3 from Zhang et al., 2017
eye pax6a expression decreased amount, abnormal	AB + MO1-fgf8a	standard conditions	Fig. 2 from Zhang et al., 2017

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Citations

Include unpublished citations

Zhang, C., Boa-Amponsem, O., Cole, G.J. (2017) Comparison of molecular marker expression in early zebrafish brain development following chronic ethanol or morpholino treatment. Experimental brain research. 235(8):2413-2423
McCarthy, N., Sidik, A., Bertrand, J.Y., Eberhart, J.K. (2016) An Fgf-Shh signaling hierarchy regulates early specification of the zebrafish skull. Developmental Biology. 415(2):261-77
Maulding, K., Padanad, M.S., Dong, J., Riley, B.B. (2014) Mesodermal Fgf10b cooperates with other Fgfs during induction of otic and epibranchial placodes in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 243(10):1275-85
Su, C.Y., Kemp, H.A., and Moens, C.B. (2014) Cerebellar development in the absence of Gbx function in zebrafish. Developmental Biology. 386(1):181-90
Shimozono, S., Iimura, T., Kitaguchi, T., Higashijima, S.I., and Miyawaki, A. (2013) Visualization of an endogenous retinoic acid gradient across embryonic development. Nature. 496(7445):363-6
Sorrell, M.R., and Waxman, J.S. (2011) Restraint of Fgf8 signaling by retinoic acid signaling is required for proper heart and forelimb formation. Developmental Biology. 358(1):44-55
Hong, S.K., and Dawid, I.B. (2009) FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1. Proceedings of the National Academy of Sciences of the United States of America. 106(7):2230-2235
Neugebauer, J.M., Amack, J.D., Peterson, A.G., Bisgrove, B.W., and Yost, H.J. (2009) FGF signalling during embryo development regulates cilia length in diverse epithelia. Nature. 458(7238):651-654
Nechiporuk, A., Linbo, T., Poss, K.D., and Raible, D.W. (2007) Specification of epibranchial placodes in zebrafish. Development (Cambridge, England). 134(3):611-623
Nechiporuk, A., Linbo, T., and Raible, D.W. (2005) Endoderm-derived Fgf3 is necessary and sufficient for inducing neurogenesis in the epibranchial placodes in zebrafish. Development (Cambridge, England). 132(16):3717-3730

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