miRNA Gene
dre-let-7e
- ID
- ZDB-MIRNAG-050103-4
- Name
- microRNA let7e
- Symbol
- dre-let-7e Nomenclature History
- Previous Names
- Type
- miRNA_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within miRNA-mediated post-transcriptional gene silencing.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Hsu et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dre-let-7e-201
(1)
|
Ensembl | 100 nt | ||
| miRNA | mirlet7e-001 (1) | 22 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Citations |
|---|---|---|---|
| Contained in | BAC | CH211-194J14 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NR_039095 (1) | |||
| Genomic | GenBank:CR936540 (1) | 187191 nt |
- Siegerist, F., Lange, T., Iervolino, A., Koppe, T.M., Zhou, W., Capasso, G., Endlich, K., Endlich, N. (2021) Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models. Scientific Reports. 11:22894
- Hsu, A.Y., Wang, D., Liu, S., Lu, J., Syahirah, R., Bennin, D.A., Huttenlocher, A., Umulis, D.M., Wan, J., Deng, Q. (2019) Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration. Proceedings of the National Academy of Sciences of the United States of America. 116(37):18561-18570
- Hsu, A.Y., Wang, D., Gurol, T., Zhou, W., Zhu, X., Lu, H.Y., Deng, Q. (2017) Overexpression of microRNA-722 fine-tunes neutrophilic inflammation by inhibiting Rac2 in zebrafish.. Disease models & mechanisms. 10(11):1323-1332
- Kasper, D.M., Moro, A., Ristori, E., Narayanan, A., Hill-Teran, G., Fleming, E., Moreno-Mateos, M., Vejnar, C.E., Zhang, J., Lee, D., Gu, M., Gerstein, M., Giraldez, A., Nicoli, S. (2017) MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos. Developmental Cell. 40:552-565.e5
- King, B.L., Yin, V.P. (2016) A Conserved MicroRNA Regulatory Circuit Is Differentially Controlled during Limb/Appendage Regeneration. PLoS One. 11:e0157106
- Narayanan, A., Hill-Teran, G., Moro, A., Ristori, E., Kasper, D.M., A Roden, C., Lu, J., Nicoli, S. (2016) In vivo mutagenesis of miRNA gene families using a scalable multiplexed CRISPR/Cas9 nuclease system. Scientific Reports. 6:32386
- Craig, T.A., Zhang, Y., Magis, A.T., Funk, C.C., Price, N.D., Ekker, S.C., Kumar, R. (2014) Detection of 1,25-Dihydroxyvitamin D-Regulated miRNAs in Zebrafish by Whole Transcriptome Sequencing. Zebrafish. 11(3):207-18
- Desvignes, T., Beam, M.J., Batzel, P., Sydes, J., Postlethwait, J.H. (2014) Expanding the annotation of zebrafish microRNAs based on small RNA sequencing. Gene. 546(2):386-9
- Xu, J., Zhang, R., Shen, Y., Liu, G., Lu, X., and Wu, C.I. (2013) The evolution of evolvability in microRNA target sites in vertebrates. Genome research. 23(11):1810-1816
- Johnston, I.A., Lee, H.T., Macqueen, D.J., Paranthaman, K., Kawashima, C., Anwar, A., Kinghorn, J.R., and Dalmay, T. (2009) Embryonic temperature affects muscle fibre recruitment in adult zebrafish: genome-wide changes in gene and microRNA expression associated with the transition from hyperplastic to hypertrophic growth phenotypes. The Journal of experimental biology. 212(Pt 12):1781-1793
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