ZFIN Lab: Qiang Li Lab

ZFIN ID: ZDB-LAB-200928-2

Qiang Li Lab

PI/Director:	Li, Qiang
Contact Person:	Li, Qiang
Email:	liq@fudan.edu.cn
URL:
Address:	399 Wanyuan Road, Shanghai, 201102
Country:	China
Phone:
Fax:
Line Designation:	fdu

GENOMIC FEATURES ORIGINATING FROM THIS LAB

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STATEMENT OF RESEARCH INTERESTS

Gene Therapy and Molecular Mechanism of Developmental Disorders

LAB MEMBERS

Jing, Wu Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Zhang, Q., Li, F., Li, T., Lin, J., Jian, J., Zhang, Y., Chen, X., Liu, T., Gou, S., Zhang, Y., Liu, X., Ji, Y., Wang, X., Li, Q. (2024) Nomo1 deficiency causes autism-like behavior in zebrafish. EMBO reports. 25(2):570-592

Deng, J., Liu, C., Hu, M., Hu, C., Lin, J., Li, Q., Xu, X. (2023) Dynamic Regulation of brsk2 in the Social and Motor Development of Zebrafish: A Developmental Behavior Analysis. International Journal of Molecular Sciences. 24(22):

Zhang, R., Sun, Y., Zhang, Q., Lin, J., Zhang, Y., Chen, X., Liu, T., Li, Q. (2023) Overexpression of miR-124-3p affects zebrafish inner ear development and hearing function via downregulation of EYA1 gene expression. Neuroscience letters. 802:137172

Wang, Y., Liu, C., Deng, J., Xu, Q., Lin, J., Li, H., Hu, M., Hu, C., Li, Q., Xu, X. (2023) Behavioral and Sensory Deficits Associated with Dysfunction of GABAergic System in a Novel shank2-Deficient Zebrafish Model. International Journal of Molecular Sciences. 24(3):

Wu, C., Hu, B., Wang, L., Wu, X., Gu, H., Dong, H., Yan, J., Qi, Z., Zhang, Q., Chen, H., Yu, B., Hu, S., Qian, Y., Dong, S., Li, Q., Wang, X., Long, J. (2022) Assessment of stromal SCD-induced drug resistance of PDAC using 3D-printed zPDX model chips. iScience. 26:105723105723

Chen, X., Zhang, Q., Lin, J., Zhang, Y., Zhang, Y., Gui, Y., Zhang, R., Liu, T., Li, Q. (2022) The tissue-specificity associated region and motif of an emx2 downstream enhancer CNE2.04 in zebrafish. Gene expression patterns : GEP. 45:119269

Gui, Y., Zhang, Y., Zhang, Q., Chen, X., Wang, F., Wu, F., Gui, Y., Li, Q. (2022) The functional verification and analysis of Fugu promoter of cardiac gene tnni1a in zebrafish. Cells & development. 171:203801

Deng, J., Wang, Y., Hu, M., Lin, J., Li, Q., Liu, C., Xu, X. (2022) Deleterious Variation in BR Serine/Threonine Kinase 2 Classified a Subtype of Autism. Frontiers in molecular neuroscience. 15:904935

Wu, F., Yang, Q., Mi, Y., Wang, F., Cai, K., Zhang, Y., Wang, Y., Wang, X., Gui, Y., Li, Q. (2022) miR-29b-3p Inhibitor Alleviates Hypomethylation-Related Aberrations Through a Feedback Loop Between miR-29b-3p and DNA Methylation in Cardiomyocytes. Frontiers in cell and developmental biology. 10:788799

Zhang, Q., Sun, S., Zhang, Y., Wang, X., Li, Q. (2022) Identification of Scd5 as a functional regulator of visceral fat deposition and distribution. iScience. 25:103916

Zhang, Q., Li, T., Lin, J., Zhang, Y., Li, F., Chen, X., Wang, X., Li, Q. (2022) Deficiency of nde1 in zebrafish induces brain inflammatory responses and autism-like behavior. iScience. 25:103876

Li, F., Lin, J., Li, T., Jian, J., Zhang, Q., Zhang, Y., Liu, X., Li, Q. (2022) Rrn3 gene knockout affects ethanol-induced locomotion in adult heterozygous zebrafish. Psychopharmacology. 239(2):621-630

Liu, C., Wang, Y., Deng, J., Lin, J., Hu, C., Li, Q., Xu, X. (2021) Social Deficits and Repetitive Behaviors Are Improved by Early Postnatal Low-Dose VPA Intervention in a Novel shank3-Deficient Zebrafish Model. Frontiers in neuroscience. 15:682054

Zhang, Q., Li, T., Zhang, Y., Lin, J., Chen, X., Gui, Y., Li, Q. (2020) Comparative sequence analysis and functional validation identified a retina-specific enhancer around zic5 and zic2a. Gene expression patterns : GEP. 39:119162

Zhang, Y., Wang, F., Wu, F., Wang, Y., Wang, X., Gui, Y., Li, Q. (2020) Tnni1b-ECR183-d2, an 87 bp cardiac enhancer of zebrafish. PeerJ. 8:e10289

Li, T., Li, F., Lin, J., Zhang, Y., Zhang, Q., Sun, Y., Chen, X., Xu, M., Wang, X., Li, Q. (2020) Deletion of c16orf45 in zebrafish results in a low fertilization rate and increased thigmotaxis. Developmental psychobiology. 62(8):1003-1010

Wu, J., Yang, Y., He, Y., Li, Q., Wang, X., Sun, C., Wang, L., An, Y., Luo, F. (2019) EFTUD2 gene deficiency disrupts osteoblast maturation and inhibits chondrocyte differentiation via activation of the p53 signaling pathway. Human genomics. 13:63

Liu, L., Fei, F., Zhang, R., Wu, F., Yang, Q., Wang, F., Sun, S., Zhao, H., Li, Q., Wang, L., Wang, Y., Gui, Y., Wang, X. (2019) Combinatorial genetic replenishments in myocardial and outflow tract tissues restore heart function in tnnt2 mutant zebrafish. Biology Open. 8(12):

Yang, Q., Wu, F., Wang, F., Cai, K., Zhang, Y., Sun, Q., Zhao, X., Gui, Y., Li, Q. (2019) Impact of DNA methyltransferase inhibitor 5-azacytidine on cardiac development of zebrafish in vivo and cardiomyocyte proliferation, apoptosis, and the homeostasis of gene expression in vitro. Journal of cellular biochemistry. 120(10):17459-17471

Zhou, J., Zhao, H., Zhang, L., Liu, C., Feng, S., Ma, J., Li, Q., Ke, H., Wang, X., Liu, L., Liu, C., Su, X., Liu, Y., Yang, S. (2019) Integrated analysis of RNA-seq and microRNA-seq depicts miRNA-mRNA networks involved in stripe patterns of Botia superciliaris skin. Functional & integrative genomics. 19(5):827-838

Wang, F., Lin, J., Jian, J., Wang, Y.H., Guo, N., Li, Q. (2019) Protection role of resveratrol against alcohol-induced heart defect in zebrafish embryos. Chinese Medical Journal. 132:990-993

Wang, F., Yang, Q., Wu, F., Zhang, Y., Sun, S., Wang, X., Gui, Y., Li, Q. (2019) Identification of a 42-bp heart-specific enhancer of the notch1b gene in zebrafish embryos. Developmental Dynamics : an official publication of the American Association of Anatomists. 248(6):426-436