ZFIN ID: ZDB-LAB-200917-1
Dahai Yang Lab
PI/Director: Yang, Dahai
Contact Person: Yang, Dahai
Email: dahaiyang@ecust.edu.cn
URL: http://biotech.ecust.edu.cn/2019/0423/c7935a88262/page.htm
Address: East China University of Science and Technology 130 Meilong Rd. Shanghai, 200237
Country: China
Phone: 86-21-64253065
Fax:
Line Designation: eib


GENOMIC FEATURES ORIGINATING FROM THIS LAB
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STATEMENT OF RESEARCH INTERESTS
Dr. Dahai Yang’s group is interested in fundamental research in microbial-host interactions, innate immune responses, the pathogenesis of inflammatory disease. Specifically, the research focuses on mechanistic studies to understand the role of bacterial infection-induced pyroptosis in regulating multi-organ dysfunction during sepsis. Several approaches that include biochemical reconstitution, cell biology, analysis of genetically modified mutant mice, and zebrafish genetics to identify new components in pathogen-induced inflammasome activation and to further reveal the underlying biochemical mechanism involved in the interaction between microbial/endogenous molecules and sepsis.


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Wang, Z., Gu, Z., Hou, Q., Chen, W., Mu, D., Zhang, Y., Liu, Q., Liu, Z., Yang, D. (2020) Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic-Acute Kidney Injury In Vivo. Journal of immunology (Baltimore, Md. : 1950). 204(7):1929-1942