ZFIN ID: ZDB-LAB-190401-1
Maegawa Lab
PI/Director: Maegawa, Shingo
Contact Person: Maegawa, Shingo
Email: maegawa.shingo.7m@kyoto-u.ac.jp
URL:
Address: Yoshida-Honmachi, Sakyo, Kyoto, 606-8501
Country: Japan
Phone: +81-75-753-9136
Fax: +81-75-753-3145
Line Designation: ko


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 2 genomic features


STATEMENT OF RESEARCH INTERESTS
We are interested in early embryogenesis, especially mechanisms for organizer formation regulated by maternal factors.
In addition, we are studying about novel methods for genome editing.


LAB MEMBERS


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Mu, A., Cao, Z., Huang, D., Hosokawa, H., Maegawa, S., Takata, M. (2023) Effects of the major formaldehyde catalyzer ADH5 on phenotypes of fanconi anemia zebrafish model. Molecular biology reports. 50(10):8385-8395
Suzuki, S., Kimura, R., Maegawa, S., Nakata, M., Hagiwara, M. (2020) Different effects of methylphenidate and atomoxetine on the behavior and brain transcriptome of zebrafish. Molecular brain. 13:70
Tanaka, S., Yoshioka, S., Nishida, K., Hosokawa, H., Kakizuka, A., Maegawa, S. (2018) In vivo targeted single-nucleotide editing in zebrafish. Scientific Reports. 8:11423
Tanaka, S., Hosokawa, H., Weinberg, E.S., Maegawa, S. (2017) Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish. Developmental Biology. 424(2):189-197
Aoyama, Y., Moriya, N., Tanaka, S., Taniguchi, T., Hosokawa, H., Maegawa, S. (2015) A Novel Method for Rearing Zebrafish by Using Freshwater Rotifers (Brachionus calyciflorus). Zebrafish. 12(4):288-95
Varga, M., Maegawa, S., and Weinberg, E.S. (2011) Correct anteroposterior patterning of the zebrafish neurectoderm in the absence of the early dorsal organizer. BMC Developmental Biology. 11(1):26
Hayashi, S., Yoshida, M., Fujiwara, T., Maegawa, S., and Fukusaki, E. (2011) Single-embryo metabolomics and systematic prediction of developmental stage in zebrafish. Zeitschrift fur Naturforschung. C, Journal of biosciences. 66(3-4):191-198
Cruz, C., Maegawa, S., Weinberg, E.S., Wilson, S.W., Dawid, I.B., and Kudoh, T. (2010) Induction and patterning of trunk and tail neural ectoderm by the homeobox gene eve1 in zebrafish embryos. Proceedings of the National Academy of Sciences of the United States of America. 107(8):3564-3569
Tang, X., Maegawa, S., Weinberg, E.S., and Dmochowski, I.J. (2007) Regulating Gene Expression in Zebrafish Embryos Using Light-Activated, Negatively Charged Peptide Nucleic Acids. Journal of the American Chemical Society. 129(36):11000-11001
Varga, M., Maegawa, S., Bellipanni, G., and Weinberg, E.S. (2007) Chordin expression, mediated by Nodal and FGF signaling, is restricted by redundant function of two beta-catenins in the zebrafish embryo. Mechanisms of Development. 124(9-10):775-791
Maegawa, S., Varga, M., and Weinberg, E.S. (2006) FGF signaling is required for {beta}-catenin-mediated induction of the zebrafish organizer. Development (Cambridge, England). 133(16):3265-3276
Bellipanni, G., Varga, M., Maegawa, S., Imai, Y., Kelly, C., Myers, A.P., Chu, F., Talbot, W.S., and Weinberg, E.S. (2006) Essential and opposing roles of zebrafish β-catenins in the formation of dorsal axial structures and neurectoderm. Development (Cambridge, England). 133(7):1299-1309
Saito, T., Fujimoto, T., Maegawa, S., Inoue, K., Tanaka, M., Arai, K., and Yamaha, E. (2006) Visualization of primordial germ cells in vivo using GFP-nos1 3'UTR mRNA. The International journal of developmental biology. 50(8):691-699
Gore, A.V., Maegawa, S., Cheong, A., Gilligan, P.C., Weinberg, E.S., and Sampath, K. (2005) The zebrafish dorsal axis is apparent at the four-cell stage. Nature. 438(7070):1030-1035
Tsang, M., Maegawa, S., Kiang, A., Habas, R., Weinberg, E., and Dawid, I.B. (2004) A role for MKP3 in axial patterning of the zebrafish embryo. Development (Cambridge, England). 131(12):2769-2779
Hashimoto, Y., Maegawa, S., Nagai, T., Yamaha, E., Suzuki, H., Yasuda, K., and Inoue, K. (2004) Localized maternal factors are required for zebrafish germ cell formation. Developmental Biology. 268(1):152-161
Jin, Y., Suzuki, H., Maegawa, S., Endo, H., Sugano, S., Hashimoto, K., Yasuda, K., and Inoue, K. (2003) A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG. The EMBO journal. 22(4):905-912
Maegawa, S., Yamashita, M., Yasuda, K., and Inoue, K. (2002) Zebrafish DAZ-like protein controls translation via the sequence 'GUUC'. Genes to cells : devoted to molecular & cellular mechanisms. 7(9):971-984
Suzuki, H., Maegawa, S., Nishibu, T., Sugiyama, T., Yasuda, K., and Inoue, K. (2000) Vegetal localization of the maternal mRNA encoding an EDEN-BP/Bruno-like protein in zebrafish. Mechanisms of Development. 93(1-2):205-209
Maegawa, S., Yasuda, K., and Inoue, K. (1999) Maternal mRNA localization of zebrafish DAZ-like gene. Mechanisms of Development. 81(1-2):223-226
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.