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ZFIN ID: ZDB-LAB-170214-6
Zhen-Yu Du Lab
PI/Director: Du, Zhen-Yu
Co-PI / Senior
Zhang, Mei-Ling
Contact Person: Li, Dong-Liang
Address: Laboratory of Aquaculture Nutrition and Environmental Health (LANEH) School of Life Sciences, East China Normal University 500 Dongchuan Road, Minhang District, Shanghai 200241, CHINA CHINA
Country: China
Phone: 86-21-54345354
Line Designation: ecn

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Li, Dong-Liang Post-Doc Li, Jia-Min Graduate Student Limbu, Samwel Michele Graduate Student
Lu, Dong-Liang Graduate Student Wang, Jing Graduate Student Qiao, Fang Administrative Staff

Han, S.L., Liu, Y., Limbu, S.M., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2020) The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish. Fish physiology and biochemistry. 47(1):173-188
Li, L.Y., Lv, H.B., Jiang, Z.Y., Qiao, F., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2020) Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish. The Journal of physiology. 598(20):4537-4553
Li, L.Y., Li, J.M., Ning, L.J., Lu, D.L., Luo, Y., Ma, Q., Limbu, S.M., Li, D.L., Chen, L.Q., Lodhi, I.J., Degrace, P., Zhang, M.L., Du, Z.Y. (2020) Mitochondrial Fatty Acid β-Oxidation Inhibition Promotes Glucose Utilization and Protein Deposition through Energy Homeostasis Remodeling in Fish. The Journal of nutrition. 150(9):2322-2335
Sun, S.X., Wu, J.L., Lv, H.B., Zhang, H.Y., Zhang, J., Limbu, S.M., Qiao, F., Chen, L.Q., Yang, Y., Zhang, M.L., Du, Z.Y. (2020) Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways. Journal of hazardous materials. 394:122537
Ma, Q., Hu, C.T., Yue, J., Luo, Y., Qiao, F., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) High-carbohydrate diet promotes the adaptation to acute hypoxia in zebrafish. Fish physiology and biochemistry. 46(2):665-679
Tan, F., Limbu, S.M., Qian, Y., Qiao, F., Du, Z.Y., Zhang, M. (2019) The Responses of Germ-Free Zebrafish (Danio rerio) to Varying Bacterial Concentrations, Colonization Time Points, and Exposure Duration. Frontiers in microbiology. 10:2156
Wang, J., Han, S.L., Lu, D.L., Li, L.Y., Limbu, S.M., Li, D.L., Zhang, M.L., Du, Z.Y. (2019) Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells. Frontiers in Physiology. 10:1077
Sun, S.X., Zhang, Y.N., Lu, D.L., Wang, W.L., Limbu, S.M., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) Concentration-dependent effects of 17β-estradiol and bisphenol A on lipid deposition, inflammation and antioxidant response in male zebrafish (Danio rerio). Chemosphere. 237:124422
Shi, C., Lu, Y., Zhai, G., Huang, J., Shang, G., Lou, Q., Li, D., Jin, X., He, J., Du, Z., Gui, J., Yin, Z. (2019) Hyperandrogenism in POMCa-deficient zebrafish enhances somatic growth without increasing adiposity. Journal of molecular cell biology. 12(4):291-304
Lu, D.L., Ma, Q., Sun, S.X., Zhang, H., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) Reduced oxidative stress increases acute cold stress tolerance in zebrafish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 235:166-173
Lu, D.L., Ma, Q., Wang, J., Li, L.Y., Han, S.L., Limbu, S.M., Li, D.L., Chen, L.Q., Zhang, M.L., Du, Z.Y. (2019) Fasting enhances cold resistance in fish through stimulating lipid catabolism and autophagy. The Journal of physiology. 597(6):1585-1603
Sheng, Y., Ren, H., Limbu, S.M., Sun, Y., Qiao, F., Zhai, W., Du, Z.Y., Zhang, M. (2018) The Presence or Absence of Intestinal Microbiota Affects Lipid Deposition and Related Genes Expression in Zebrafish (Danio rerio).. Frontiers in microbiology. 9:1124
Li, J.M., Li, L.Y., Qin, X., Degrace, P., Demizieux, L., Limbu, S.M., Wang, X., Zhang, M.L., Li, D.L., Du, Z.Y. (2018) Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish. Frontiers in Physiology. 9:509
Zhou, L., Limbu, S.M., Qiao, F., Du, Z.Y., Zhang, M. (2018) Influence of Long-Term Feeding Antibiotics on the Gut Health of Zebrafish. Zebrafish. 15(4):340-348
Zhou, L., Limbu, S.M., Shen, M., Zhai, W., Qiao, F., He, A., Du, Z.Y., Zhang, M. (2017) Environmental concentrations of antibiotics impair zebrafish gut health. Environmental pollution (Barking, Essex : 1987). 235:245-254
Yang, B.Y., Zhai, G., Gong, Y.L., Su, J.Z., Peng, X.Y., Shang, G.H., Han, D., Jin, J.Y., Liu, H.K., Du, Z.Y., Yin, Z., Xie, S.Q. (2017) Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. American journal of physiology. Endocrinology and metabolism. 315(1):E38-E51
Peng, X., Shang, G., Wang, W., Chen, X., Lou, Q., Zhai, G., Li, D., Du, Z., Ye, Y., Jin, X., He, J., Zhang, Y., Yin, Z. (2017) Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)2D3.. Cell Reports. 19:1444-1455
Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Corrigendum: Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:44970
Li, J.M., Li, L.Y., Qin, X., Ning, L.J., Lu, D.L., Li, D.L., Zhang, M.L., Wang, X., Du, Z.Y. (2017) Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio. Scientific Reports. 7:40815
Liu, H.J., Zhang, C.Y., Song, F., Xiao, T., Meng, J., Zhang, Q., Liang, C.L., Li, S., Wang, J., Zhang, B., Liu, Y.R., Sun, T., Zhou, H.G. (2015) A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor γ with Excellent Effect on Insulin Resistance and Type 2 Diabetes. The Journal of pharmacology and experimental therapeutics. 353:573-81