ZFIN Lab: Yong Zhu Lab

ZFIN ID: ZDB-LAB-150713-1

Yong Zhu Lab

PI/Director:	Zhu, Yong
Contact Person:	Zhu, Yong
Email:	ZHUY@ecu.edu
URL:	http://core.ecu.edu/biol/zhuy/labwebsite/home.htm
Address:	Molecular and Comparative Endocrinology Laboratory, Department of Biology, Howell Science, East Carolina University, 1000 E. 5th Street, Greenville, NC 27858, USA
Country:	United States
Phone:	252-328-6504
Fax:	252-328-4178
Line Designation:	ecu

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 19 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Thet, Zayer Graduate Student

Wu, Xinjun Graduate Student

Liu, Dongteng Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

He, Y., Carver, J.J., Erickson, T., Le Pabic, P., Zhu, Y. (2023) Dynamic and broad expression of adamts9 in developing and adult zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 252(12):1449-1461

Carver, J.J., Zhu, Y. (2022) Metzincin Metalloproteases in PGC Migration and Gonadal Sex Conversion. General and comparative endocrinology. 330:114137

Huang, J., Sun, C., Liu, D.T., Zhao, N.N., Jordan, S.A., Zhu, Y., Chen, S.X. (2022) Nuclear Progestin Receptor Mediated Linkage of Blood Coagulation and Ovulation. Endocrinology. 163(7):

Carver, J.J., Carrell, S.C., Chilton, M.W., Brown, J.N., Yong, L., Zhu, Y., Issa, F.A. (2021) Nuclear androgen and progestin receptors inversely affect aggression and social dominance in male zebrafish (Danio rerio). Hormones and behavior. 134:105012

Carver, J.J., He, Y., Zhu, Y. (2021) Delay in primordial germ cell migration in adamts9 knockout zebrafish. Scientific Reports. 11:8545

Wu, X.J., Williams, M.J., Kew, K.A., Converse, A., Thomas, P., Zhu, Y. (2021) Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish. Frontiers in endocrinology. 12:637691

Wu, X.J., Liu, D.T., Chen, S., Hong, W., Zhu, Y. (2020) Impaired oocyte maturation and ovulation in membrane progestin receptor (mPR) knockouts in zebrafish. Molecular and Cellular Endocrinology. 511:110856

Lee, M.H., Wu, X., Zhu, Y. (2019) RNA-binding protein PUM2 regulates mesenchymal stem cell fate via repression of JAK2 and RUNX2 mRNAs. Journal of Cellular Physiology. 235(4):3874-3885

Liu, D.T., Hong, W.S., Chen, S.X., Zhu, Y. (2019) Upregulation of adamts9 by gonadotropin in preovulatory follicles of zebrafish. Molecular and Cellular Endocrinology. 499:110608

Wu, X.J., Zhu, Y. (2019) Downregulation of nuclear progestin receptor (Pgr) and subfertility in double knockouts of progestin receptor membrane component 1 (pgrmc1) and pgrmc2 in zebrafish. General and comparative endocrinology. 285:113275

Wu, X.J., Jermaul Williams, M., Rameshkumar Patel, P., Ann Kew, K., Zhu, Y. (2019) Subfertility and reduced progestin synthesis in Pgrmc2 knockout zebrafish. General and comparative endocrinology. 282:113218

Jansch Carter, N., Adam Roach, Z., Marie Byrnes, M., Zhu, Y. (2019) Adamts9 is Necessary for Ovarian Development in Zebrafish. General and comparative endocrinology. 277:130-140

Chen, L., Xiang, W., Mo, J., Sun, C., Zhou, Y., Wu, X., He, Z. (2019) [Wnt/β-catenin signaling pathway involved in the expression and drug resistance of abcb4 gene in transgenic zebrafish induced by chemotherapeutic drugs]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 35:134-139

Wu, X.J., Thomas, P., Zhu, Y. (2018) Pgrmc1 Knockout Impairs Oocyte Maturation in Zebrafish. Frontiers in endocrinology. 9:560

Liu, D.T., Carter, N.J., Wu, X.J., Hong, W.S., Chen, S.X., Zhu, Y. (2018) Progestin and Nuclear Progestin Receptor Are Essential for Upregulation of Metalloproteinase in Zebrafish Preovulatory Follicles. Frontiers in endocrinology. 9:517

Aizen, J., Pang, Y., Harris, C., Converse, A., Zhu, Y., Aguirre, M.A., Thomas, P. (2018) Roles of progesterone receptor membrane component 1 and membrane progestin receptor alpha in regulation of zebrafish oocyte maturation. General and comparative endocrinology. 263:51-61

Yong, L., Thet, Z., Zhu, Y. (2017) Genetic editing of the androgen receptor contributes to impaired male courtship behavior in zebrafish. The Journal of experimental biology. 220(Pt 17):3017-3021

Liu, D., Brewer, M.S., Chen, S., Hong, W., Zhu, Y. (2017) Transcriptomic Signatures for Ovulation in Vertebrates. General and comparative endocrinology. 247:74-86

Chen, S.X., Yang, X.Z., Deng, Y., Huang, J., Li, Y., Sun, Q., Yu, C.P., Zhu, Y., Hong, W.S. (2017) Silver nanoparticles induce oocyte maturation in zebrafish (Danio rerio). Chemosphere. 170:51-60

Wang, C., Liu, D., Chen, W., Ge, W., Hong, W., Zhu, Y., Chen, S.X. (2016) Progestin increases the expression of gonadotropins in pituitaries of male Zebrafish. The Journal of endocrinology. 230(1):143-56

Zhu, Y., Liu, D., Shaner, Z.C., Chen, S., Hong, W., Stellwag, E.J. (2015) Nuclear progestin receptor (pgr) knockouts in zebrafish demonstrate role for pgr in ovulation but not in rapid non-genomic steroid mediated meiosis resumption. Frontiers in endocrinology. 6:37

Zhu, Y., Wang, D., Wang, F., Li, T., Dong, L., Liu, H., Ma, Y., Jiang, F., Yin, H., Yan, W., Luo, M., Tang, Z., Zhang, G., Wang, Q., Zhang, J., Zhou, J., and Yu, J. (2013) A comprehensive analysis of GATA-1-regulated miRNAs reveals miR-23a to be a positive modulator of erythropoiesis. Nucleic acids research. 41(7):4129-43

Hanna, R.N., and Zhu, Y. (2011) Controls of meiotic signaling by membrane or nuclear progestin receptor in zebrafish follicle-enclosed oocytes. Molecular and Cellular Endocrinology. 337(1-2):80-8

Diotel, N., Servili, A., Gueguen, M.M., Mironov, S., Pellegrini, E., Vaillant, C., Zhu, Y., Kah, O., and Anglade, I. (2011) Nuclear progesterone receptors are up-regulated by estrogens in neurons and radial glial progenitors in the brain of zebrafish. PLoS One. 6(11):e28375

Carnevali, O., Tosti, L., Speciale, C., Peng, C., Zhu, Y., and Maradonna, F. (2010) DEHP Impairs Zebrafish Reproduction by Affecting Critical Factors in Oogenesis. PLoS One. 5(4):e10201

Hanna, R.N., Daly, S.C., Pang, Y., Anglade, I., Kah, O., Thomas, P., and Zhu, Y. (2010) Characterization and Expression of the Nuclear Progestin Receptor in Zebrafish Gonads and Brain. Biology of reproduction. 82(1):112-122

Nguyen, N., and Zhu, Y. (2009) Prolactin functions as a survival factor during zebrafish embryogenesis. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 153(1):88-93

Hanna, R.N., and Zhu, Y. (2009) Expression of membrane progestin receptors in zebrafish (Danio rerio) oocytes, testis and pituitary. General and comparative endocrinology. 161(1):153-157

Nguyen, N., Stellwag, E.J., and Zhu, Y. (2008) Prolactin-dependent modulation of organogenesis in the vertebrate: Recent discoveries in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 148(4):370-380

Xie, C., Nguyen, N., Zhu, Y., and Li, Y.Q. (2007) Detection of the Recombinant Proteins in Single Transgenic Microbial Cell Using Laser Tweezers and Raman Spectroscopy. Analytical chemistry. 79(24):9269-9275

Zhu, Y., Song, D., Tran, N.T., and Nguyen, N. (2007) The effects of the members of growth hormone family knockdown in zebrafish development. General and comparative endocrinology. 150(3):395-404

Nguyen, N., Sugimoto, M., and Zhu, Y. (2006) Production and purification of recombinant somatolactin beta and its effects on melanosome aggregation in zebrafish. General and comparative endocrinology. 145(2):182-187

Thomas, P., Pang, Y., Zhu, Y., Detweiler, C., and Doughty, K. (2004) Multiple rapid progestin actions and progestin membrane receptor subtypes in fish. Steroids. 69(8-9):567-573

Zhu, Y., Bond, J., and Thomas, P. (2003) Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proceedings of the National Academy of Sciences of the United States of America. 100(5):2237-2242

Zhu, Y., Rice, C.D., Pang, Y., Pace, M., and Thomas, P. (2003) Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. Proceedings of the National Academy of Sciences of the United States of America. 100(5):2231-2236