ZFIN Lab: Martin Lab

ZFIN ID: ZDB-LAB-101004-1

Martin Lab

PI/Director:	Martin, Paul
Contact Person:	Martin, Paul
Email:	paul.martin@bristol.ac.uk
URL:	http://www.embryowound.info
Address:	Departments of Physiology & Biochemistry School of Medical Sciences University Walk Bristol BS8 1TD UK
Country:	United Kingdom
Phone:	+44 (0)117 331 2298
Fax:	+44 (0)117 331 2288
Line Designation:	bsl

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 9 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Jones, Rebecca Amy Graduate Student

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Ward, J., Martin, P. (2023) Live imaging studies reveal how microclots and the associated inflammatory response enhance cancer cell extravasation. Journal of Cell Science. 136(18):

López-Cuevas, P., Xu, C., Severn, C.E., Oates, T.C.L., Cross, S.J., Toye, A.M., Mann, S., Martin, P. (2022) Macrophage Reprogramming with Anti-miR223-Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(35):e2202717

Okuda, K.S., Keyser, M.S., Gurevich, D.B., Sturtzel, C., Mason, E.A., Paterson, S., Chen, H., Scott, M., Condon, N.D., Martin, P., Distel, M., Hogan, B.M. (2021) Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis. eLIFE. 10:

López-Cuevas, P., Cross, S.J., Martin, P. (2021) Modulating the Inflammatory Response to Wounds and Cancer Through Infection. Frontiers in cell and developmental biology. 9:676193

Weavers, H., Martin, P. (2020) The cell biology of inflammation: From common traits to remarkable immunological adaptations. The Journal of cell biology. 219(7):

Gurevich, D.B., French, K.E., Collin, J.D., Cross, S.J., Martin, P. (2019) Live imaging the Foreign Body Response reveals how dampening inflammation reduces fibrosis. Journal of Cell Science. 133(5):

Bevan, L., Lim, Z.W., Venkatesh, B., Riley, P.R., Martin, P., Richardson, R.J. (2019) Specific macrophage populations promote both cardiac scar deposition and subsequent resolution in adult zebrafish. Cardiovascular research. 116(7):1357-1371

van den Berg, M.C.W., MacCarthy-Morrogh, L., Carter, D., Morris, J., Ribeiro Bravo, I., Feng, Y., Martin, P. (2019) Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation. Cell Reports. 27:2837-2846.e4

Greenhough, A., Bagley, C., Heesom, K.J., Gurevich, D.B., Gay, D., Bond, M., Collard, T.J., Paraskeva, C., Martin, P., Sansom, O.J., Malik, K., Williams, A.C. (2018) Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Molecular Medicine. 10(11):

Morris, J.L., Cross, S.J., Lu, Y., Kadler, K.E., Lu, Y., Dallas, S.L., Martin, P. (2018) Live imaging of collagen deposition during skin development and repair in a collagen I - GFP fusion transgenic zebrafish line. Developmental Biology. 441(1):4-11

Gurevich, D.B., Severn, C.E., Twomey, C., Greenhough, A., Cash, J., Toye, A.M., Mellor, H., Martin, P. (2018) Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression. The EMBO journal. 37(13)

Liepe, J., Sim, A., Weavers, H., Ward, L., Martin, P., Stumpf, M.P. (2016) Accurate Reconstruction of Cell and Particle Tracks from 3D Live Imaging Data. Cell systems. 3(1):102-7

Feng, Y., Santoriello, C., Mione, M., Hurlstone, A., Martin, P. (2016) Correction: Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation. PLoS Biology. 14:e1002377

Antonio, N., Bønnelykke-Behrndtz, M.L., Ward, L.C., Collin, J., Christensen, I.J., Steiniche, T., Schmidt, H., Feng, Y., Martin, P. (2015) The wound inflammatory response exacerbates growth of pre-neoplastic cells and progression to cancer. The EMBO journal. 34(17):2219-36

Feng, Y., Martin, P. (2015) Imaging innate immune responses at tumour initiation: new insights from fish and flies. Nature reviews. Cancer. 15(9):556-62

Martin, P., Nunan, R. (2015) Cellular and molecular mechanisms of repair in acute and chronic wound healing. The British journal of dermatology. 173:370-8

Jones, R.A., Feng, Y., Worth, A.J., Thrasher, A.J., Burns, S.O., and Martin, P. (2013) Modelling human Wiskott-Aldrich syndrome protein mutants in zebrafish larvae using live in vivo imaging. Journal of Cell Science. 126(Pt 18):4077-84

Lévesque, M., Feng, Y., Jones, R., and Martin, P. (2013) Inflammation drives wound hyperpigmentation by recruiting pigment cells to sites of tissue damage. Disease models & mechanisms. 6(2):508-515

Evans, M.A., Smart, N., Dube, K.N., Bollini, S., Clark, J.E., Evans, H.G., Taams, L.S., Richardson, R., Levesque, M., Martin, P., Mills, K., Riegler, J., Price, A.N., Lythgoe, M.F., and Riley, P.R. (2013) Thymosin beta4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing. Nature communications. 4:2081

Feng, Y., Renshaw, S., and Martin, P. (2012) Live Imaging of Tumor Initiation in Zebrafish Larvae Reveals a Trophic Role for Leukocyte-Derived PGE(2). Current biology : CB. 22(13):1253-1259

Williams, C.M., Feng, Y., Martin, P., and Poole, A.W. (2011) Protein kinase C alpha and beta are positive regulators of thrombus formation in vivo in a zebrafish (Danio rerio) model of thrombosis. Journal of thrombosis and haemostasis : JTH. 9(12):2457-65

Goudevenou, K., Martin, P., Yeh, Y.J., Jones, P., and Sablitzky, F. (2011) Def6 Is Required for Convergent Extension Movements during Zebrafish Gastrulation Downstream of Wnt5b Signaling. PLoS One. 6(10):e26548

Feng, Y., Santoriello, C., Mione, M., Hurlstone, A., and Martin, P. (2010) Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation. PLoS Biology. 8(12):e1000562

Cvejic, A., Hall, C., Bak-Maier, M., Flores, M.V., Crosier, P., Redd, M.J., and Martin, P. (2008) Analysis of WASp function during the wound inflammatory response - live-imaging studies in zebrafish larvae. Journal of Cell Science. 121(Pt 19):3196-3206

Redd, M.J., Kelly, G., Dunn, G., Way, M., and Martin, P. (2006) Imaging macrophage chemotaxis in vivo: Studies of microtubule function in zebrafish wound inflammation. Cell motility and the cytoskeleton. 63(7):415-422