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ZFIN ID: ZDB-LAB-100729-1
Fatkin Lab
PI/Director: Fatkin, Diane
Contact Person: Fatkin, Diane
Address: Molecular Cardiology and Biophysics Division Victor Chang Cardiac Research Institute 405 Liverpool St Darlinghurst NSW 2010 Australia
Country: Australia
Phone: +61 2 9295 8618
Fax: +61 2 9295 8601
Line Designation: vcc

Show all 6 genomic features

1. Molecular genetics of dilated cardiomyopathy and atrial fibrillation.
2. Zebrafish models of human heart disease.

Huttner, Inken Post-Doc Chand, Renee Research Staff Trivedi, Gunjan Research Staff

Pineda, S., Nikolova-Krstevski, V., Leimena, C., Atkinson, A.J., Altekoester, A.K., Cox, C.D., Jacoby, A., Huttner, I.G., Ju, Y.K., Soka, M., Ohanian, M., Trivedi, G., Kalvakuri, S., Birker, K., Johnson, R., Molenaar, P., Kuchar, D., Allen, D.G., van Helden, D.F., Harvey, R.P., Hill, A.P., Bodmer, R., Vogler, G., Dobrzynski, H., Ocorr, K., Fatkin, D. (2021) Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk. Circulation. Genomic and precision medicine. 14(2):e003144
Santiago, C.F., Huttner, I.G., Fatkin, D. (2021) Mechanisms of TTNtv-Related Dilated Cardiomyopathy: Insights from Zebrafish Models. Journal of cardiovascular development and disease. 8(2):
Hall, T.E., Wood, A.J., Ehrlich, O., Li, M., Sonntag, C.S., Cole, N.J., Huttner, I.G., Sztal, T.E., Currie, P.D. (2019) Cellular rescue in a zebrafish model of congenital muscular dystrophy type 1A. NPJ Regenerative medicine. 4:21
Huttner, I.G., Wang, L.W., Santiago, C.F., Horvat, C., Johnson, R., Cheng, D., von Frieling-Salewsky, M., Hillcoat, K., Bemand, T.J., Trivedi, G., Braet, F., Hesselson, D., Alford, K., Hayward, C.S., Seidman, J.G., Seidman, C.E., Feneley, M.P., Linke, W.A., Fatkin, D. (2018) A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance. Circulation. Genomic and precision medicine. 11:e002135
Zhang, H., Dvornikov, A.V., Huttner, I.G., Ma, X., Santiago, C.F., Fatkin, D., Xu, X. (2018) A Langendorff-like system to quantify cardiac pump function in adult zebrafish. Disease models & mechanisms. 11(9):
Wang, L.W., Kesteven, S.H., Huttner, I.G., Feneley, M.P., Fatkin, D. (2018) High-Frequency Echocardiography - Transformative Clinical and Research Applications in Humans, Mice, and Zebrafish. Circulation journal : official journal of the Japanese Circulation Society. 82(3):620-628
Wang, L.W., Huttner, I.G., Santiago, C.F., Kesteven, S.H., Yu, Z.Y., Feneley, M.P., Fatkin, D. (2017) Standardized echocardiographic assessment of cardiac function in normal adult zebrafish and heart disease models. Disease models & mechanisms. 10:63-76
Wang, L.W., Huttner, I.G., Santiago, C.F., Fatkin, D. (2016) Bradycardia in Zebrafish Heart Failure: A True Physiological Response or Anesthetic-Induced Red Herring?. Zebrafish. 13(6):475-476
Christensen, A.H., Chatelain, F.C., Huttner, I.G., Olesen, M.S., Soka, M., Feliciangeli, S., Horvat, C., Santiago, C.F., Vandenberg, J.I., Schmitt, N., Olesen, S.P., Lesage, F., Fatkin, D. (2016) The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size. Journal of Molecular and Cellular Cardiology. 97:24-35
Liang, B., Soka, M., Christensen, A.H., Olesen, M.S., Larsen, A.P., Knop, F.K., Wang, F., Nielsen, J.B., Andersen, M.N., Humphreys, D., Mann, S.A., Huttner, I.G., Vandenberg, J.I., Svendsen, J.H., Haunsø, S., Preiss, T., Seebohm, G., Olesen, S.P., Schmitt, N., and Fatkin, D. (2014) Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis. Journal of Molecular and Cellular Cardiology. 67:69-76
Huttner, I.G., Trivedi, G., Jacoby, A., Mann, S.A., Vandenberg, J.I., and Fatkin, D. (2013) A transgenic zebrafish model of a human cardiac sodium channel mutation exhibits bradycardia, conduction-system abnormalities and early death. Journal of Molecular and Cellular Cardiology. 61:123-32