ZFIN Lab: Sakaguchi Lab

ZFIN ID: ZDB-LAB-100614-1

Sakaguchi Lab

PI/Director:	Sakaguchi, Takuya
Contact Person:	Sakaguchi, Takuya
Email:	sakagut2@ccf.org
URL:
Address:	9500 Euclid Ave. NE30 Cleveland, OH 44195
Country:	United States
Phone:	216-445-9280
Fax:	216-636-5454
Line Designation:	lri

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 6 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Nussbaum, Justin M. Post-Doc

Schaub, Madeline Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Ghaffari, K., Pierce, L.X., Roufaeil, M., Gibson, I., Tae, K., Sahoo, S., Cantrell, J.R., Andersson, O., Lau, J., Sakaguchi, T.F. (2021) NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis. PLoS Genetics. 17:e1009402

DeRossi, C., Bambino, K., Morrison, J., Sakarin, I., Villacorta-Martin, C., Zhang, C., Ellis, J.L., Fiel, M.I., Ybanez, M., Lee, Y.A., Huang, K.L., Yin, C., Sakaguchi, T.F., Friedman, S.L., Villanueva, A., Chu, J. (2019) Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans. Hepatology (Baltimore, Md.). 70(6):2107-2122

Posner, M., Murray, K.L., McDonald, M.S., Eighinger, H., Andrew, B., Drossman, A., Haley, Z., Nussbaum, J., David, L.L., Lampi, K.J. (2017) The zebrafish as a model system for analyzing mammalian and native α-crystallin promoter function.. PeerJ. 5:e4093

Dimri, M., Bilogan, C., Pierce, L.X., Naegele, G., Vasanji, A., Gibson, I., McClendon, A., Tae, K., Sakaguchi, T.F. (2017) Three-dimensional structural analysis reveals a Cdk5-mediated kinase cascade regulating hepatic biliary network branching in zebrafish. Development (Cambridge, England). 144:2595-2605

Davuluri, G., Song, P., Liu, Z., Wald, D., Sakaguchi, T.F., Green, M.R., Devireddy, L. (2016) Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy. Proceedings of the National Academy of Sciences of the United States of America. 113(11):E1460-9

Posner, M., Skiba, J., Brown, M., Liang, J.O., Nussbaum, J., and Prior, H. (2013) Loss of the small heat shock protein alphaA-crystallin does not lead to detectable defects in early zebrafish lens development. Experimental Eye Research. 116:227-33

Nussbaum, J.M., Liu, L.J., Hasan, S.A., Schaub, M., McClendon, A., Stainier, D.Y., and Sakaguchi, T.F. (2013) Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis. Hepatology (Baltimore, Md.). 58(4):1326-1338

Schaub, M., Nussbaum, J., Verkade, H., Ober, E.A., Stainier, D.Y., and Sakaguchi, T.F. (2012) Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Developmental Biology. 363(1):128-137

Sakaguchi, T.F., Sadler, K.C., Crosnier, C., and Stainier, D.Y. (2008) Endothelial Signals Modulate Hepatocyte Apicobasal Polarization in Zebrafish. Current biology : CB. 18(20):1565-1571

Sakaguchi, T., Kikuchi, Y., Kuroiwa, A., Takeda, H., and Stainier, D.Y. (2006) The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish. Development (Cambridge, England). 133(20):4063-4072

Kawamura, A., Koshida, S., Hijikata, H., Sakaguchi, T., Kondoh, H., and Takada, S. (2005) Zebrafish Hairy/Enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites. Genes & Development. 19(10):1156-1161

Takeuchi, M., Nakabayashi, J., Sakaguchi, T., Yamamoto, T.S., Takahashi, H., Takeda, H., and Ueno, N. (2003) The prickle-related gene in vertebrates is essential for gastrulation cell movements. Current biology : CB. 13(8):674-679

Sakaguchi, T., Mizuno, T., and Takeda, H. (2002) Formation and patterning roles of the yolk syncytial layer. Results and problems in cell differentiation. 40:1-14

Sakaguchi, T., Kuroiwa, A., and Takeda, H. (2001) A novel sox gene, 226D7, acts downstream of Nodal signaling to specify endoderm precursors in zebrafish. Mechanisms of Development. 107(1-2):25-38

Sakaguchi, T., Kuroiwa, A., and Takeda, H. (2001) Expression of zebrafish btg-b, an anti-proliferative cofactor, during early embryogenesis. Mechanisms of Development. 104(1-2):113-115