ZFIN Lab: Marlow Lab

ZFIN ID: ZDB-LAB-080819-1

Marlow Lab

PI/Director:	Marlow, Florence
Contact Person:	Marlow, Florence
Email:	florence.marlow@mssm.edu
URL:	http://labs.icahn.mssm.edu/marlowlab/
Address:	Department of Cell, Developmental and Regenerative Biology 1468 Madison Avenue Box 1020 New York, NY 10029
Country:	United States
Phone:	718-421-4160
Fax:
Line Designation:	ae

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 20 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Bravo, P., Liu, Y., Draper, B.W., Marlow, F.L. (2023) Macrophage activation drives ovarian failure and masculinization in zebrafish. Science advances. 9:eadg7488eadg7488

Bertho, S., Kaufman, O., Lee, K., Santos-Ledo, A., Dellal, D., Marlow, F.L. (2021) A transgenic system for targeted ablation of reproductive and maternal-effect genes. Development (Cambridge, England). 148(12):

Bertho, S., Clapp, M., Banisch, T.U., Bandemer, J., Raz, E., Marlow, F.L. (2021) Zebrafish dazl regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition. Development (Cambridge, England). 148(7)

Hong, S., Feng, L., Yang, Y., Jiang, H., Hou, X., Guo, P., Marlow, F.L., Stanley, P., Wu, P. (2020) In Situ Fucosylation of the Wnt Co-receptor LRP6 Increases Its Endocytosis and Reduces Wnt/β-Catenin Signaling. Cell chemical biology. 27:1140-1150.e4

Romano, S., Kaufman, O.H., Marlow, F.L. (2020) Loss of dmrt1 restores female fates in the absence of cyp19a1a but not rbpms2a/b. Development (Cambridge, England). 147(18):

Abrams, E.W., Fuentes, R., Marlow, F.L., Kobayashi, M., Zhang, H., Lu, S., Kapp, L., Joseph, S.R., Kugath, A., Gupta, T., Lemon, V., Runke, G., Amodeo, A.A., Vastenhouw, N.L., Mullins, M.C. (2020) Molecular genetics of maternally-controlled cell divisions. PLoS Genetics. 16:e1008652

Marlow, F.L. (2020) Setting up for gastrulation in zebrafish. Current topics in developmental biology. 136:33-83

Lee, K.L., Marlow, F.L. (2019) Visualizing the Balbiani Body in Zebrafish Oocytes. Methods in molecular biology (Clifton, N.J.). 1920:277-293

Kaufman, O.H., Lee, K., Martin, M., Rothhämel, S., Marlow, F.L. (2018) rbpms2 functions in Balbiani body architecture and ovary fate. PLoS Genetics. 14:e1007489

Kim, S., Alsrhani, A., Zafreen, L., Khandekar, G., Marlow, F.L., Abrams, E.W., Mullins, M.C., Jagadeeswaran, P. (2017) G protein-coupled receptor gpr34l mutation affects thrombocyte function in zebrafish. British journal of haematology. 180(3):412-419

Santos-Ledo, A., Garcia-Macia, M., Campbell, P.D., Gronska, M., Marlow, F.L. (2017) Kinesin-1 promotes chondrocyte maintenance during skeletal morphogenesis. PLoS Genetics. 13:e1006918

Forbes, M.M., Draper, B.W., Marlow, F.L. (2017) Retraction: The polarity factor Bucky ball associates with the centrosome and promotes microtubule rearrangements to establish the oocyte axis in zebrafish. Development (Cambridge, England).

Hartung, O., Forbes, M.M., Marlow, F.L. (2016) Erratum: Zebrafish vasa is required for germ-cell differentiation and maintenance. Molecular reproduction and development. 83:1128-1130

Langdon, Y.G., Fuentes, R., Zhang, H., Abrams, E.W., Marlow, F.L., Mullins, M.C. (2016) Split top: A maternal cathepsin B that regulates dorsoventral patterning and morphogenesis. Development (Cambridge, England). 143(6):1016-28

Kaufman, O.H., Marlow, F.L. (2016) Methods to study maternal regulation of germ cell specification in zebrafish. Methods in cell biology. 134:1-32

Campbell, P.D., Heim, A.E., Smith, M.Z., Marlow, F.L. (2015) Kinesin-1 interacts with Bucky ball to form germ cells and is required to pattern the zebrafish body axis. Development (Cambridge, England). 142(17):2996-3008

Li-Villarreal, N., Forbes, M.M., Loza, A.J., Chen, J., Ma, T., Helde, K., Moens, C.B., Shin, J., Sawada, A., Hindes, A.E., Dubrulle, J., Schier, A.F., Longmore, G.D., Marlow, F.L., Solnica-Krezel, L. (2015) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (Cambridge, England). 142(15):2704-18

Campbell, P.D., Chao, J.A., Singer, R.H., Marlow, F.L. (2015) Dynamic visualization of transcription and RNA subcellular localization in zebrafish. Development (Cambridge, England). 142(7):1368-74

Feng, L., Jiang, H., Wu, P., Marlow, F.L. (2014) Negative feedback regulation of Wnt signaling via N-linked fucosylation in zebrafish. Developmental Biology. 395(2):268-86

Campbell, P.D., Shen, K., Sapio, M.R., Glenn, T.D., Talbot, W.S., Marlow, F.L. (2014) Unique Function of Kinesin Kif5A in Localization of Mitochondria in Axons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:14717-32

Hartung, O., Forbes, M.M., Marlow, F.L. (2014) Zebrafish vasa is required for germ-cell differentiation and maintenance. Molecular reproduction and development. 81(10):946-61

Ge, X., Grotjahn, D., Welch, E., Lyman-Gingerich, J., Holguin, C., Dimitrova, E., Abrams, E.W., Gupta, T., Marlow, F.L., Yabe, T., Adler, A., Mullins, M.C., Pelegri, F. (2014) Hecate/Grip2a acts to reorganize the cytoskeleton in the symmetry-breaking event of embryonic axis induction. PLoS Genetics. 10(6):e1004422

Jiang, H., Zheng, T., Lopez-Aguilar, A., Feng, L., Kopp, F., Marlow, F.L., and Wu, P. (2014) Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chemistry. 25(4):698-706

Heim, A.E., Hartung, O., Rothhämel, S., Ferreira, E., Jenny, A., and Marlow, F.L. (2014) Oocyte polarity requires a Bucky ball-dependent feedback amplification loop. Development (Cambridge, England). 141(4):842-854

Campbell, P.D., and Marlow, F.L. (2013) Temporal and tissue specific gene expression patterns of the zebrafish kinesin-1 heavy chain family, kif5s, during development. Gene expression patterns : GEP. 13(7):271-279

Kapp, L.D., Abrams, E.W., Marlow, F.L., and Mullins, M.C. (2013) The integrator complex subunit 6 (ints6) confines the dorsal organizer in vertebrate embryogenesis. PLoS Genetics. 9(10):e1003822

Zaucker, A., Mercurio, S., Sternheim, N., Talbot, W.S., and Marlow, F.L. (2013) notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish. Disease models & mechanisms. 6(5):1246-59

Li, X., Roszko, I., Sepich, D.S., Ni, M., Hamm, H.E., Marlow, F.L., and Solnica-Krezel, L. (2013) Gpr125 modulates Dishevelled distribution and planar cell polarity signaling. Development (Cambridge, England). 140(14):3028-3039

Nair, S., Marlow, F., Abrams, E., Kapp, L., Mullins, M.C., and Pelegri, F. (2013) The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo. PLoS Genetics. 9(4):e1003448

Santos-Ledo, A., Jenny, A., and Marlow, F.L. (2013) Comparative gene expression analysis of the fmnl family of formins during zebrafish development and implications for tissue specific functions. Gene expression patterns : GEP. 13(1-2):30-37

Abrams, E.W., Zhang, H., Marlow, F.L., Kapp, L., Lu, S., and Mullins, M.C. (2012) Dynamic Assembly of Brambleberry Mediates Nuclear Envelope Fusion during Early Development. Cell. 150(3):521-532

Jiang, H., Feng, L., Soriano Del Amo, D., Seidel Iii, R.D., Marlow, F., and Wu, P. (2011) Imaging glycans in zebrafish embryos by metabolic labeling and bioorthogonal click chemistry. Journal of visualized experiments : JoVE.

Soriano Del Amo, D., Wang, W., Jiang, H., Besanceney, C., Yan, A.C., Levy, M., Liu, Y., Marlow, F.L., and Wu, P. (2010) Biocompatible Copper(I) Catalysts for in Vivo Imaging of Glycans. Journal of the American Chemical Society. 132(47):16893-16899

Gupta, T., Marlow, F.L., Ferriola, D., Mackiewicz, K., Dapprich, J., Monos, D., and Mullins, M.C. (2010) Microtubule actin crosslinking factor 1 regulates the Balbiani body and animal-vegetal polarity of the zebrafish oocyte. PLoS Genetics. 6(8):e1001073

Nojima, H., Rothhämel, S., Shimizu, T., Kim, C.H., Yonemura, S., Marlow, F.L., and Hibi, M. (2010) Syntabulin, a motor protein linker, controls dorsal determination. Development (Cambridge, England). 137(6):923-933

Mei, W., Lee, K.W., Marlow, F.L., Miller, A.L., and Mullins, M.C. (2009) hnRNP I is required to generate the Ca2+ signal that causes egg activation in zebrafish. Development (Cambridge, England). 136(17):3007-3017

Bontems, F., Stein, A., Marlow, F., Lyautey, J., Gupta, T., Mullins, M.C., and Dosch, R. (2009) Bucky Ball Organizes Germ Plasm Assembly in Zebrafish. Current biology : CB. 19(5):414-422

Alvarez-Delfin, K., Morris, A.C., Snelson, C.D., Gamse, J.T., Gupta, T., Marlow, F.L., Mullins, M.C., Burgess, H.A., Granato, M., and Fadool, J.M. (2009) Tbx2b is required for ultraviolet photoreceptor cell specification during zebrafish retinal development. Proceedings of the National Academy of Sciences of the United States of America. 106(6):2023-2028

Marlow, F.L., and Mullins, M.C. (2008) Bucky ball functions in Balbiani body assembly and animal-vegetal polarity in the oocyte and follicle cell layer in zebrafish. Developmental Biology. 321(1):40-50

Blaser, H., Reichman-Fried, M., Castanon, I., Dumstrei, K., Marlow, F.L., Kawakami, K., Solnica-Krezel, L., Heisenberg, C.P., and Raz, E. (2006) Migration of zebrafish primordial germ cells: a role for Myosin contraction and cytoplasmic flow. Developmental Cell. 11(5):613-627

Marlow, F., Gonzalez, E.M., Yin, C., Rojo, C., and Solnica-Krezel, L. (2004) No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish. Development (Cambridge, England). 131(1):203-216

Marlow, F.L. (2003) Genetic dissection of zebrafish gastrulation and tail morphogenesis. Ph.D. Thesis. :198P

Jessen, J.R., Topczewski, J., Bingham, S., Sepich, D.S., Marlow, F., Chandrasekhar, A., and Solnica-Krezel, L. (2002) Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nature cell biology. 4(8):610-615

Solnica-Krezel, L., Marlow, F., Topczewski, J., Jessen, J., and Sepich, D. (2002) Regulation of cell polarity during zebrafish gastrulation. Developmental Biology. 247(2):479

Marlow, F., Topczewski, J., Sepich, D., and Solnica-Krezel, L. (2002) Zebrafish rho kinase 2 acts downstream of wnt11 to mediate cell polarity and effective convergence and extension movements. Current biology : CB. 12(11):876-884

Solnica-Krezel, L., Topczewski, J., Sepich, D., Myers, D., Marlow, F., and Jessen, J. (2001) Genetic control of convergent extension movements during zebrafish gastrulation. Developmental Biology. 235(1):175 (#17)

Sepich, D.S., Myers, D.C., Short, R., Topczewski, J., Marlow, F., and Solnica-Krezel, L. (2000) Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension. Genesis (New York, N.Y. : 2000). 27(4):159-173

Marlow, F., Zwartkruis, F., Malicki, J., Neuhauss, S.C.F., Abbas, L., Weaver, M., Driever, W., and Solnica-Krezel, L. (1998) Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish. Developmental Biology. 203:382-399