Community Action Needed: Please respond to the NIH RFI
ZFIN ID: ZDB-LAB-070906-1
James G. Patton Lab
PI/Director: Patton, James G.
Contact Person: Patton, James G.
Email: James.G.Patton@Vanderbilt.edu
URL: http://www.cas.vanderbilt.edu/pattonlab/pattonlab.html
Address: Department of Biological Sciences Vanderbilt University 2301 Vanderbilt Place VU Station B 351820 Nashville TN 37235-1820
Country: United States
Phone: 615-322-4738
Fax: 615-343-6707
Line Designation: vu


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 3 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Flynt, Alex Graduate Student Li, Nan Graduate Student Thatcher, Elizabeth Graduate Student


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Kent, M.R., Kara, N., Patton, J.G. (2021) Inhibition of GABAA-ρ receptors induces retina regeneration in zebrafish. Neural regeneration research. 16:367-374
Konar, G.J., Ferguson, C., Flickinger, Z., Kent, M.R., Patton, J.G. (2021) miRNAs and Müller Glia Reprogramming During Retina Regeneration. Frontiers in cell and developmental biology. 8:632632
Didiano, D., Abner, J.J., Hinger, S.A., Flickinger, Z., Kent, M., Clement, M.A., Balaiya, S., Liu, Q., Dai, X., Levine, E.M., Patton, J.G. (2020) Induction of a proliferative response in the zebrafish retina by injection of extracellular vesicles. Experimental Eye Research. 200:108254
Kara, N., Kent, M.R., Didiano, D., Rajaram, K., Zhao, A., Summerbell, E.R., Patton, J.G. (2019) The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration. Cell Reports. 28:2037-2047.e4
Neitzel, L.R., Spencer, Z.T., Nayak, A., Cselenyi, C.S., Benchabane, H., Youngblood, C.Q., Zouaoui, A., Ng, V., Stephens, L., Hann, T., Patton, J.G., Robbins, D., Ahmed, Y., Lee, E. (2019) Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway. Mechanisms of Development. 156:20-31
Kara, N., Wei, C., Commanday, A.C., Patton, J.G. (2017) miR-27 regulates chondrogenesis by suppressing Focal Adhesion Kinase during pharyngeal arch development. Developmental Biology. 429(1):321-334
Rao, M.B., Didiano, D., Patton, J.G. (2017) Neurotransmitter-Regulated Regeneration in the Zebrafish Retina. Stem Cell Reports. 8(4):831-842
Flynt, A.S., Rao, M., Patton, J.G. (2017) Blocking Zebrafish MicroRNAs with Morpholinos. Methods in molecular biology (Clifton, N.J.). 1565:59-78
Khuansuwan, S., Clanton, J.A., Dean, B.J., Patton, J.G., Gamse, J.T. (2016) A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex. Development (Cambridge, England). 143(14):2641-50
Broadus, M.R., Chen, T.W., Neitzel, L.R., Ng, V.H., Jodoin, J.N., Lee, L.A., Salic, A., Robbins, D.J., Capobianco, A.J., Patton, J.G., Huppert, S.S., Lee, E. (2016) Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. 15(9):1920-9
Yin, L., Maddison, L.A., Li, M., Kara, N., LaFave, M.C., Varshney, G.K., Burgess, S.M., Patton, J.G., Chen, W. (2015) Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs. Genetics. 200(2):431-41
Olena, A.F., Rao, M.B., Thatcher, E.J., Wu, S.Y., Patton, J.G. (2015) miR-216a regulates snx5, a novel notch signaling pathway component, during zebrafish retinal development. Developmental Biology. 400(1):72-81
Rajaram, K., Harding, R.L., Bailey, T., Patton, J.G., Hyde, D.R. (2014) Dynamic miRNA Expression Patterns During Retina Regeneration in Zebrafish: Reduced Dicer or miRNA Expression Suppresses Proliferation of Müller Glia-Derived Neuronal Progenitor Cells. Developmental dynamics : an official publication of the American Association of Anatomists. 243(12):1591-605
Rajaram, K., Summerbell, E.R., Patton, J.G. (2014) Technical brief: Constant intense light exposure to lesion and initiate regeneration in normally pigmented zebrafish. Molecular Vision. 20:1075-84
Andrews, O.E., Cha, D.J., Wei, C., Patton, J.G. (2014) RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription. Scientific Reports. 4:5222
Wei, C., Thatcher, E.J., Olena, A.F., Cha, D.J., Perdigoto, A.L., Marshall, A.F., Carter, B.D., Broadie, K., and Patton, J.G. (2013) miR-153 Regulates SNAP-25, Synaptic Transmission, and Neuronal Development. PLoS One. 8(2):e57080
Wei, C., Salichos, L., Wittgrove, C.M., Rokas, A., and Patton, J.G. (2012) Transcriptome-wide analysis of small RNA expression in early zebrafish development. RNA (New York, N.Y.). 18(5):915-929
Li, N., Wei, C., Olena, A.F., and Patton, J.G. (2011) Regulation of endoderm formation and left-right asymmetry by miR-92 during early zebrafish development. Development (Cambridge, England). 138(9):1817-1826
Flynt, A.S., and Patton, J.G. (2010) Crosstalk between planar cell polarity signaling and miR-8 control of NHERF1-mediated actin reorganization. Cell cycle (Georgetown, Tex.). 9(2):235-237
Flynt, A.S., Thatcher, E.J., Burkewitz, K., Li, N., Liu, Y., and Patton, J.G. (2009) miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos. The Journal of cell biology. 185(1):115-127
Thatcher, E.J., Paydar, I., Anderson, K.K., and Patton, J.G. (2008) Regulation of zebrafish fin regeneration by microRNAs. Proceedings of the National Academy of Sciences of the United States of America. 105(47):18384-18389
Li, N., Flynt, A.S., Kim, H.R., Solnica-Krezel, L., and Patton, J.G. (2008) Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites. Nucleic acids research. 36(13):4277-4285
Thatcher, E.J., Bond, J.M., Paydar, I., and Patton, J.G. (2008) Genomic Organization of Zebrafish microRNAs. BMC Genomics. 9:253