ZFIN ID: ZDB-LAB-040113-2
Bruce Lab
PI/Director: Bruce, Ashley
Contact Person: Bruce, Ashley
Email: ashley.bruce@utoronto.ca
URL: http://labs.csb.utoronto.ca/bruce
Address: Department of Cell & Systems Biology University of Toronto 25 Harbord Street Toronto, Ontario M5S 3G5 CANADA
Country: Canada
Phone: (416) 946-0436
Fax: (416) 978-8532
Line Designation: uot


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 5 genomic features


STATEMENT OF RESEARCH INTERESTS
Axial patterning, morphogenesis and cell fate specification during development.


LAB MEMBERS
Bae, Koeun Graduate Student Fei, Zhonghui Graduate Student


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Willoughby, P.M., Allen, M., Yu, J., Korytnikov, R., Chen, T., Liu, Y., So, I., Macpherson, N., Mitchell, J.A., Fernandez-Gonzalez, R., Bruce, A.E.E. (2021) The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium. eLIFE. 10:
Bruce, A.E.E., Heisenberg, C.P. (2020) Mechanisms of zebrafish epiboly: A current view. Current topics in developmental biology. 136:319-341
Rutherford, N.E., Wong, A.H., Bruce, A.E.E. (2019) Spatio-temporal characterization of dynamic epithelial filopodia during zebrafish epiboly. Developmental dynamics : an official publication of the American Association of Anatomists. 248(10):997-1008
Fei, Z., Bae, K., Parent, S.E., Wan, H., Goodwin, K., Theisen, U., Tanentzapf, G., Bruce, A.E.E. (2018) A cargo model of yolk syncytial nuclear migration during zebrafish epiboly. Development (Cambridge, England). 146(1):
Hunter, M.V., Willoughby, P.M., Bruce, A.E.E., Fernandez-Gonzalez, R. (2018) Oxidative Stress Orchestrates Cell Polarity to Promote Embryonic Wound Healing. Developmental Cell. 47:377-387.e4
West, J.J., Zulueta-Coarasa, T., Maier, J.A., Lee, D.M., Bruce, A.E.E., Fernandez-Gonzalez, R., Harris, T.J.C. (2017) An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation under Stress. Current biology : CB. 27(15):2260-2270.e5
Hanwell, D., Hutchinson, S.A., Collymore, C., Bruce, A.E., Louis, R., Ghalami, A., Allison, W.T., Ekker, M., Eames, B.F., Childs, S., Kurrasch, D.M., Gerlai, R., Thiele, T., Scott, I., Ciruna, B., Dowling, J.J., McFarlane, S., Huang, P., Wen, X.Y., Akimenko, M.A., Waskiewicz, A.J., Drapeau, P., Babiuk, L.A., Dragon, D., Smida, A., Buret, A.G., O'Grady, E., Wilson, J., Sowden-Plunkett, L., Tropepe, V. (2016) Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus. Zebrafish. 13 Suppl 1:S153-63
Bruce, A.E. (2016) Zebrafish Epiboly: Spreading thin over the yolk. Developmental dynamics : an official publication of the American Association of Anatomists. 245(3):244-58
Luu, O., Damm, E.W., Parent, S.E., Barua, D., Smith, T.H., Wen, J.W., Lepage, S.E., Nagel, M., Ibrahim-Gawel, H., Huang, Y., Bruce, A.E., Winklbauer, R. (2015) PAPC mediates self/non-self-distinction during Snail1-dependent tissue separation. The Journal of cell biology. 208:839-856
Nelson, A.C., Cutty, S.J., Niini, M., Stemple, D.L., Flicek, P., Houart, C., Bruce, A., Wardle, F.C. (2014) Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression. BMC Biology. 12:81
Lepage, S.E., and Bruce, A.E. (2014) Dynamin-dependent maintenance of epithelial integrity is essential for zebrafish epiboly. Bioarchitecture. 4(1):31-34
Lepage, S.E., Tada, M., and Bruce, A.E. (2014) Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly. Developmental Biology. 385(1):52-66
Du, S., Draper, B.W., Mione, M., Moens, C.B., and Bruce, A.E. (2012) Differential regulation of epiboly initiation and progression by zebrafish Eomesodermin A. Developmental Biology. 362(1):11-23
Siddiqui, M., Sheikh, H., Tran, C., and Bruce, A.E. (2010) The tight junction component Claudin E is required for zebrafish epiboly. Developmental dynamics : an official publication of the American Association of Anatomists. 239(2):715-722
Lepage, S.E., and Bruce, A.E. (2010) Zebrafish epiboly: mechanics and mechanisms. The International journal of developmental biology. 54(8-9):1213-1228
Carfagnini, A.G., Rodd, F.H., Jeffers, K.B., and Bruce, A.E.E. (2009) The effects of habitat complexity on aggression and fecundity in zebrafish (Danio rerio). Environmental biology of fishes. 86(3):403-409
Dixon Fox, M., and Bruce, A.E. (2009) Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b. Development (Cambridge, England). 136(10):1675-1685
Hsu, K., Sheikh, H., Bruce, A.E.E. (2009) Expression pattern of the family 30 (zinc transporter), member 7, slc30a7. ZFIN Direct Data Submission.
Lepage, S.E., and Bruce, A.E. (2008) Characterization and comparative expression of zebrafish calpain system genes during early development. Developmental dynamics : an official publication of the American Association of Anatomists. 237(3):819-829
Miao, M., Bruce, A.E., Bhanji, T., Davis, E.C., and Keeley, F.W. (2007) Differential expression of two tropoelastin genes in zebrafish. Matrix biology : journal of the International Society for Matrix Biology. 26(2):115-124
Walton, R.Z., Bruce, A.E., Olivey, H.E., Najib, K., Johnson, V., Earley, J.U., Ho, R.K., and Svensson, E.C. (2006) Fog1 is required for cardiac looping in zebrafish. Developmental Biology. 289(2):482-493
Bruce, A.E., Howley, C., Dixon Fox, M., and Ho, R.K. (2005) T-box gene eomesodermin and the homeobox-containing Mix/Bix gene mtx2 regulate epiboly movements in the zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists. 233(1):105-114
Bruce, A.E., Howley, C., Zhou, Y., Vickers, S.L., Silver, L.M., King, M.L., and Ho, R.K. (2003) The maternally expressed zebrafish T-box gene eomesodermin regulates organizer formation. Development (Cambridge, England). 130(22):5503-5517
Bruce, A.E., Oates, A.C., Prince, V.E., and Ho, R.K. (2001) Additional hox clusters in the zebrafish: divergent expression patterns belie equivalent activities of duplicate hoxB5 genes. Evolution & development. 3(3):127-144
Oates, A.C., Bruce, A.E., and Ho, R.K. (2000) Too much interference: injection of double-stranded RNA has nonspecific effects in the zebrafish embryo. Developmental Biology. 224(1):20-28
Bruce, A.E.E., Prince, V.E., and Ho, R.K. (1999) Comparison of expression and function of two hoxb5 paralogues in the zebrafish. Developmental Biology. 210:188