ZFIN Lab: Neuhauss Lab

ZFIN ID: ZDB-LAB-000629-1

Neuhauss Lab

PI/Director:	Neuhauss, Stephan
Contact Person:	Neuhauss, Stephan
Email:	stephan.neuhauss@imls.uzh.ch
URL:	http://www.imls.uzh.ch/Research/Neurobiology/Neuhauss.html
Address:	Institute of Molecular Life Sciences University of Zürich Winterthurerstrasse 190 Zürich, CH - 8057 Switzerland
Country:	Switzerland
Phone:	41-44-635-6040
Fax:	41-44-635-6897
Line Designation:	zh

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 8 genomic features

STATEMENT OF RESEARCH INTERESTS

We are interested in studying vision and in particular the retina using the genetic and behavioral tools. We have identified a number of visually impaired mutations employing optokinetic and optomotor behavioral assays. These mutations are currently further characterized morphologically, physiologically and gentically. Such forward genetic studies are complemented by morpholino knock-down experiments. The ultimate goal of our research is to identify genes involved in building a functional visual system and specify their function in the processing of visual information. We are particularly interested in creating models for humans eye diseases and address mechanisms of light adaptation

LAB MEMBERS

Penton Ribas, David Post-Doc	Garbelli, Marco Graduate Student	Hotz, Adriana Graduate Student
Schlegel, Domino Graduate Student	Viegas, Filipe Graduate Student	Kristiansen, Kara Fish Facility Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Zhang, Z., Cao, Y., Caviglia, S., Agrawal, P., Neuhauss, S.C.F., Ahmed, D. (2024) A vibrating capillary for ultrasound rotation manipulation of zebrafish larvae. Lab on a Chip. 24(4):764-775

Letelier, J., Buono, L., Almuedo-Castillo, M., Zang, J., Mounieres, C., González-Díaz, S., Polvillo, R., Sanabria-Reinoso, E., Corbacho, J., Sousa-Ortega, A., Diez Del Corral, R., Neuhauss, S.C.F., Martínez-Morales, J.R. (2023) Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network. eLIFE. 12:

Voigt, F.F., Reuss, A.M., Naert, T., Hildebrand, S., Schaettin, M., Hotz, A.L., Whitehead, L., Bahl, A., Neuhauss, S.C.F., Roebroeck, A., Stoeckli, E.T., Lienkamp, S.S., Aguzzi, A., Helmchen, F. (2023) Reflective multi-immersion microscope objectives inspired by the Schmidt telescope. Nature Biotechnology. 42(1):65-71

Masek, M., Zang, J., Mateos, J.M., Garbelli, M., Ziegler, U., Neuhauss, S.C.F., Bachmann-Gagescu, R. (2023) Studying the morphology, composition and function of the photoreceptor primary cilium in zebrafish. Methods in cell biology. 175:9712897-128

Durrer, J., Agrawal, P., Ozgul, A., Neuhauss, S.C.F., Nama, N., Ahmed, D. (2022) A robot-assisted acoustofluidic end effector. Nature communications. 13:6370

Myren-Svelstad, S., Jamali, A., Ophus, S.S., D'gama, P.P., Ostenrath, A.M., Mutlu, A.K., Hoffshagen, H.H., Hotz, A.L., Neuhauss, S.C.F., Jurisch-Yaksi, N., Yaksi, E. (2022) Elevated photic response is followed by a rapid decay and depressed state in ictogenic networks. Epilepsia. 63:2543-2560

Özsoy, Ç., Hotz, A.L., Rieser, N.N., Chen, Z., Deán-Ben, X.L., Neuhauss, S.C.F., Razansky, D. (2022) Volumetric optoacoustic neurobehavioral tracking of epileptic seizures in freely-swimming zebrafish larvae. Frontiers in molecular neuroscience. 15:1004518

Ciampi, L., Mantica, F., López-Blanch, L., Permanyer, J., Rodriguez-Marín, C., Zang, J., Cianferoni, D., Jiménez-Delgado, S., Bonnal, S., Miravet-Verde, S., Ruprecht, V., Neuhauss, S.C.F., Banfi, S., Carrella, S., Serrano, L., Head, S.A., Irimia, M. (2022) Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision. Proceedings of the National Academy of Sciences of the United States of America. 119:e2117090119

Tuschl, K., White, R.J., Trivedi, C., Valdivia, L.E., Niklaus, S., Bianco, I.H., Dadswell, C., González-Méndez, R., Sealy, I.M., Neuhauss, S.C.F., Houart, C., Rihel, J., Wilson, S.W., Busch-Nentwich, E.M. (2022) Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish. Disease models & mechanisms. 15(6)

Masek, M., Etard, C., Hofmann, C., Hülsmeier, A.J., Zang, J., Takamiya, M., Gesemann, M., Neuhauss, S.C.F., Hornemann, T., Strähle, U., Bachmann-Gagescu, R. (2022) Loss of the Bardet-Biedl protein Bbs1 alters photoreceptor outer segment protein and lipid composition. Nature communications. 13:1282

Hotz, A.L., Jamali, A., Rieser, N.N., Niklaus, S., Aydin, E., Myren-Svelstad, S., Lalla, L., Jurisch-Yaksi, N., Yaksi, E., Neuhauss, S.C.F. (2021) Loss of glutamate transporter eaat2a leads to aberrant neuronal excitability, recurrent epileptic seizures, and basal hypoactivity. Glia. 70(1):196-214

Schlegel, D.K., Ramkumar, S., von Lintig, J., Neuhauss, S.C. (2021) Disturbed retinoid metabolism upon loss of rlbp1a impairs cone function and leads to subretinal lipid deposits and photoreceptor degeneration in the zebrafish retina. eLIFE. 10:

Glasauer, S.M.K., Triemer, T., Neef, A.B., Neuhauss, S.C.F., Luedtke, N.W. (2021) DNA template strand segregation in developing zebrafish. Cell chemical biology. 28(11):1638-1647.e4

Zang, J., Gesemann, M., Keim, J., Samardzija, M., Grimm, C., Neuhauss, S.C. (2021) Circadian regulation of vertebrate cone photoreceptor function. eLIFE. 10:

Schreier, V.N., Loehr, M.O., Deng, T., Lattmann, E., Hajnal, A., Neuhauss, S.C.F., Luedtke, N.W. (2020) Fluorescent dATP for DNA Synthesis In Vivo. ACS Chemical Biology. 15(11):2996-3003

Latour, B.L., Van De Weghe, J.C., Rusterholz, T.D., Letteboer, S.J., Gomez, A., Shaheen, R., Gesemann, M., Karamzade, A., Asadollahi, M., Barroso-Gil, M., Chitre, M., Grout, M.E., van Reeuwijk, J., van Beersum, S.E., Miller, C.V., Dempsey, J.C., Morsy, H., Bamshad, M.J., Nickerson, D.A., Neuhauss, S.C., Boldt, K., Ueffing, M., Keramatipour, M., Sayer, J.A., Alkuraya, F.S., Bachmann-Gagescu, R., Roepman, R., Doherty, D. (2020) Dysfunction of the ciliary ARMC9/TOGARAM1 protein module causes Joubert syndrome. The Journal of Clinical Investigation. 130(8):4423-4439

Ali, Z., Zang, J., Lagali, N., Schmitner, N., Salvenmoser, W., Mukwaya, A., Neuhauss, S.C.F., Jensen, L.D., Kimmel, R.A. (2020) Photoreceptor Degeneration Accompanies Vascular Changes in a Zebrafish Model of Diabetic Retinopathy. Investigative ophthalmology & visual science. 61:43

Chen, Z., Luciani, A., Mateos, J.M., Barmettler, G., Giles, R.H., Neuhauss, S.C.F., Devuyst, O. (2019) Transgenic zebrafish modeling low-molecular-weight proteinuria and lysosomal storage diseases. Kidney International. 97(6):1150-1163

Schlegel, D.K., Glasauer, S.M.K., Mateos, J.M., Barmettler, G., Ziegler, U., Neuhauss, S.C.F. (2019) A New Zebrafish Model for CACNA2D4-Dysfunction. Investigative ophthalmology & visual science. 60:5124-5135

Bachmann-Gagescu, R., Neuhauss, S.C. (2019) The photoreceptor cilium and its diseases. Current opinion in genetics & development. 56:22-33

Haug, M.F., Berger, M., Gesemann, M., Neuhauss, S.C.F. (2019) Differential expression of PKCα and -β in the zebrafish retina. Histochemistry and cell biology. 151(6):521-530

Ojeda Naharros, I., Cristian, F.B., Zang, J., Gesemann, M., Ingham, P.W., Neuhauss, S.C.F., Bachmann-Gagescu, R. (2018) Publisher Correction: The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance. Scientific Reports. 8:12534

Neuhauss, S.C.F. (2018) Sensory Biology: How to Structure a Tailor-Made Retina. Current biology : CB. 28:R737-R739

Dona, M., Slijkerman, R., Lerner, K., Broekman, S., Wegner, J., Howat, T., Peters, T., Hetterschijt, L., Boon, N., de Vrieze, E., Sorusch, N., Wolfrum, U., Kremer, H., Neuhauss, S., Zang, J., Kamermans, M., Westerfield, M., Phillips, J., van Wijk, E. (2018) Usherin defects lead to early-onset retinal dysfunction in zebrafish. Experimental Eye Research. 173:148-159

Naharros, I.O., Cristian, F.B., Zang, J., Gesemann, M., Ingham, P.W., Neuhauss, S.C.F., Bachmann-Gagescu, R. (2018) The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance. Scientific Reports. 8:2211

Haug, M.F., Gesemann, M., Berger, M., Neuhauss, S.C.F. (2018) Phylogeny and distribution of protein kinase C variants in the zebrafish. The Journal of comparative neurology. 526(7):1097-1109

Ojeda Naharros, I., Gesemann, M., Mateos, J.M., Barmettler, G., Forbes, A., Ziegler, U., Neuhauss, S.C.F., Bachmann-Gagescu, R. (2017) Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors. PLoS Genetics. 13:e1007150

Mateos, J.M., Barmettler, G., Doehner, J., Ojeda Naharros, I., Guhl, B., Neuhauss, S.C.F., Kaech, A., Bachmann-Gagescu, R., Ziegler, U. (2017) Correlative Super-resolution and Electron Microscopy to Resolve Protein Localization in Zebrafish Retina. Journal of visualized experiments : JoVE. (129)

Stainier, D.Y.R., Raz, E., Lawson, N.D., Ekker, S.C., Burdine, R.D., Eisen, J.S., Ingham, P.W., Schulte-Merker, S., Yelon, D., Weinstein, B.M., Mullins, M.C., Wilson, S.W., Ramakrishnan, L., Amacher, S.L., Neuhauss, S.C.F., Meng, A., Mochizuki, N., Panula, P., Moens, C.B. (2017) Guidelines for morpholino use in zebrafish. PLoS Genetics. 13:e1007000

Niklaus, S., Neuhauss, S.C.F. (2017) Genetic approaches to retinal research in zebrafish. Journal of neurogenetics. 31(3):70-87

Sugano, Y., Cianciolo Cosentino, C., Loffing-Cueni, D., Neuhauss, S.C.F., Loffing, J. (2017) Comparative transcriptomic analysis identifies evolutionarily conserved gene products in the vertebrate renal distal convoluted tubule. Pflugers Archiv : European journal of physiology. 469(7-8):859-867

Van De Weghe, J.C., Rusterholz, T.D.S., Latour, B., Grout, M.E., Aldinger, K.A., Shaheen, R., Dempsey, J.C., Maddirevula, S., Cheng, Y.H., Phelps, I.G., Gesemann, M., Goel, H., Birk, O.S., Alanzi, T., Rawashdeh, R., Khan, A.O., Bamshad, M.J., Nickerson, D.A., Neuhauss, S.C.F., Dobyns, W.B., Alkuraya, F.S., Roepman, R., Bachmann-Gagescu, R., Doherty, D. (2017) Mutations in ARMC9, which Encodes a Basal Body Protein, Cause Joubert Syndrome in Humans and Ciliopathy Phenotypes in Zebrafish. American journal of human genetics. 101(1):23-36

Niklaus, S., Cadetti, L., Vom Berg-Maurer, C.M., Lehnherr, A., Hotz, A.L., Forster, I.C., Gesemann, M., Neuhauss, S.C.F. (2017) Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters. eNeuro. 4(3)

Martella, A., Sepe, R.M., Silvestri, C., Zang, J., Fasano, G., Carnevali, O., De Girolamo, P., Neuhauss, S.C., Sordino, P., Di Marzo, V. (2016) Important role of endocannabinoid signaling in the development of functional vision and locomotion in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30(12):4275-4288

Fehr, A.G., Ruetten, M., Seth-Smith, H.M., Nufer, L., Voegtlin, A., Lehner, A., Greub, G., Crosier, P.S., Neuhauss, S.C., Vaughan, L. (2016) A Zebrafish Model for Chlamydia Infection with the Obligate Intracellular Pathogen Waddlia chondrophila.. Frontiers in microbiology. 7:1829

Glasauer, S.M., Wäger, R., Gesemann, M., Neuhauss, S.C. (2016) mglur6b:EGFP transgenic zebrafish suggest novel functions of metabotropic glutamate signaling in retina and other brain regions. The Journal of comparative neurology. 524(12):2363-78

Eshwar, A.K., Tall, B.D., Gangiredla, J., Gopinath, G.R., Patel, I.R., Neuhauss, S.C., Stephan, R., Lehner, A. (2016) Linking Genomo- and Pathotype: Exploiting the Zebrafish Embryo Model to Investigate the Divergent Virulence Potential among Cronobacter spp. PLoS One. 11(6):e0158428

Baumann, L., Ros, A., Rehberger, K., Neuhauss, S.C., Segner, H. (2016) Thyroid disruption in zebrafish (Danio rerio) larvae: Different molecular response patterns lead to impaired eye development and visual functions. Aquatic toxicology (Amsterdam, Netherlands). 172:44-55

Sugano, Y., Lindenmeyer, M.T., Auberger, I., Ziegler, U., Segerer, S., Cohen, C.D., Neuhauss, S.C., Loffing, J. (2015) The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney International. 88(5):1047-56

Bachmann-Gagescu, R., Dona, M., Hetterschijt, L., Tonnaer, E., Peters, T., de Vrieze, E., Mans, D.A., van Beersum, S.E., Phelps, I.G., Arts, H.H., Keunen, J.E., Ueffing, M., Roepman, R., Boldt, K., Doherty, D., Moens, C.B., Neuhauss, S.C., Kremer, H., van Wijk, E. (2015) The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking. PLoS Genetics. 11:e1005575

Carmean, V., Yonkers, M.A., Tellez, M.B., Willer, J.R., Willer, G.B., Gregg, R.G., Geisler, R., Neuhauss, S.C., Ribera, A.B. (2015) pigk mutation underlies macho behavior and affects Rohon-Beard cell excitability. Journal of neurophysiology. 114(2):1146-57

Zang, J., Keim, J., Kastenhuber, E., Gesemann, M., Neuhauss, S.C. (2015) Recoverin depletion accelerates cone photoresponse recovery. Open Biology. 5(8)

Gopal, S.R., Chen, D.H., Chou, S.W., Zang, J., Neuhauss, S.C., Stepanyan, R., McDermott, B.M., Alagramam, K.N. (2015) Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:10188-201

Fehr, A., Eshwar, A.K., Neuhauss, S.C., Ruetten, M., Lehner, A., Vaughan, L. (2015) Evaluation of zebrafish as a model to study the pathogenesis of the opportunistic pathogen Cronobacter turicensis. Emerging microbes & infections. 4:e29

Haug, M.F., Gesemann, M., Lazovic, V., Neuhauss, S.C. (2015) Eumetazoan Cryptochrome Phylogeny and Evolution. Genome biology and evolution. 7(2):601-19

Ingold, E., Vom Berg-Maurer, C.M., Burckhardt, C.J., Lehnherr, A., Rieder, P., Keller, P.J., Stelzer, E.H., Greber, U.F., Neuhauss, S.C., Gesemann, M. (2015) Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A. Biology Open. 4(2):146-54

Zahnleiter, D., Hauer, N.N., Kessler, K., Uebe, S., Sugano, Y., Neuhauss, S.C., Giessl, A., Ekici, A.B., Blessing, H., Sticht, H., Dörr, H.G., Reis, A., Thiel, C.T. (2015) MAP4 Dependent Regulation of Microtubule Formation Affects Centrosome, Cilia and Golgi Architecture as A Central Mechanism in Growth Regulation. Human Mutation. 36(1):87-97

Sirisi, S., Folgueira, M., López-Hernández, T., Minieri, L., Pérez-Rius, C., Gaitán-Peñas, H., Zang, J., Martínez, A., Capdevila-Nortes, X., de la Villa, P., Roy, U., Alia, A., Neuhauss, S., Ferroni, S., Nunes, V., Estévez, R., Barrallo-Gimeno, A. (2014) Megalencephalic Leukoencephalopathy with subcortical Cysts protein 1 regulates glial surface localization of GLIALCAM from fish to humans. Human molecular genetics. 23(19):5069-86

Hodel, C., Niklaus, S., Heidemann, M., Klooster, J., Kamermans, M., Biehlmaier, O., Gesemann, M., Neuhauss, S.C. (2014) Myosin VIIA is a Marker for the Cone Accessory Outer Segment in Zebrafish. Anatomical record (Hoboken, N.J. : 2007). 297:1777-84

Huber-Reggi, S.P., Mueller, K., Straumann, D., Huang, M.Y., Neuhauss, S.C. (2014) Individual Larvae of the Zebrafish Mutant belladonna Display Multiple Infantile Nystagmus-like Waveforms that Are Influenced by Viewing Conditions. Investigative ophthalmology & visual science. 55(6):3971-8

Mueller, K.P., and Neuhauss, S.C. (2014) Sunscreen for fish: co-option of UV light protection for camouflage. PLoS One. 9(1):e87372

Tuz, K., Bachmann-Gagescu, R., O'Day, D.R., Hua, K., Isabella, C.R., Phelps, I.G., Stolarski, A.E., O'Roak, B.J., Dempsey, J.C., Lourenco, C., Alswaid, A., Bönnemann, C.G., Medne, L., Nampoothiri, S., Stark, Z., Leventer, R.J., Topçu, M., Cansu, A., Jagadeesh, S., Done, S., Ishak, G.E., Glass, I.A., Shendure, J., Neuhauss, S.C., Haldeman-Englert, C.R., Doherty, D., and Ferland, R.J. (2014) Mutations in CSPP1 cause primary cilia abnormalities and Joubert syndrome with or without Jeune asphyxiating thoracic dystrophy. American journal of human genetics. 94(1):62-72

Chen, C.C., Bockisch, C.J., Bertolini, G., Olasagasti, I., Neuhauss, S.C., Weber, K.P., Straumann, D., and Huang, M.Y. (2014) Velocity storage mechanism in zebrafish larvae. The Journal of physiology. 592(Pt 1):203-14

von Niederhäusern, V., Kastenhuber, E., Stäuble, A., Gesemann, M., and Neuhauss, S.C. (2013) Phylogeny and expression of canonical transient receptor potential (TRPC) genes in developing zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(12):1427-41

Kastenhuber, E., Gesemann, M., Mickoleit, M., and Neuhauss, S.C. (2013) Phylogenetic analysis and expression of zebrafish transient receptor potential melastatin family genes. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(11):1236-49

Sugano, Y., and Neuhauss, S.C. (2013) Reverse genetics tools in zebrafish: A forward dive into endocrinology. General and comparative endocrinology. 188:303-8

Haug, M.F., Gesemann, M., Mueller, T., and Neuhauss, S.C. (2013) Phylogeny and expression divergence of metabotropic glutamate receptor genes in the brain of zebrafish (Danio rerio). The Journal of comparative neurology. 521(7):1533-1560

Dooley, C.M., Schwarz, H., Mueller, K.P., Mongera, A., Konantz, M., Neuhauss, S.C., Nüsslein-Volhard, C., and Geisler, R. (2013) Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease. Pigment cell & melanoma research. 26(2):205-217

Kalueff, A.V., Gebhardt, M., Stewart, A.M., Cachat, J.M., Brimmer, M., Chawla, J.S., Craddock, C., Kyzar, E.J., Roth, A., Landsman, S., Gaikwad, S., Robinson, K., Baatrup, E., Tierney, K., Shamchuk, A., Norton, W., Miller, N., Nicolson, T., Braubach, O., Gilman, C.P., Pittman, J., Rosemberg, D.B., Gerlai, R., Echevarria, D., Lamb, E., Neuhauss, S.C., Weng, W., and Bally-Cuif, L. (2013) Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond. Zebrafish. 10(1):70-86

Huber-Reggi, S.P., Mueller, K.P., and Neuhauss, S.C. (2013) Analysis of optokinetic response in zebrafish by computer-based eye tracking. Methods in molecular biology (Clifton, N.J.). 935:139-160

Huber-Reggi, S.P., Chen, C.C., Grimm, L., Straumann, D., Neuhauss, S.C., and Huang, M.Y. (2012) Severity of Infantile Nystagmus Syndrome-Like Ocular Motor Phenotype Is Linked to the Extent of the Underlying Optic Nerve Projection Defect in Zebrafish belladonna Mutant. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(50):18079-18086

Mueller, K.P., and Neuhauss, S.C. (2012) Light perception: more than meets the eyes. Current biology : CB. 22(21):R912-914

Gestri, G., Link, B.A., and Neuhauss, S.C. (2012) The visual system of zebrafish and its use to model human ocular diseases. Developmental Neurobiology. 72(3):302-327

Mueller, K.P., and Neuhauss, S.C. (2012) Automated visual choice discrimination learning in zebrafish (Danio rerio). Journal of Integrative Neuroscience. 11(1):73-85

Glover, G., Mueller, K.P., Söllner, C., Neuhauss, S.C., and Nicolson, T. (2012) The Usher gene cadherin 23 is expressed in the zebrafish brain and a subset of retinal amacrine cells. Molecular Vision. 18:2309-2322

Huang, Y.Y., Haug, M.F., Gesemann, M., and Neuhauss, S.C. (2012) Novel expression patterns of metabotropic glutamate receptor 6 in the zebrafish nervous system. PLoS One. 7(4):e35256

Kalueff, A.V., Stewart, A.M., Kyzar, E.J., Cachat, J., Gebhardt, M., Landsman, S., Robinson, K., Maximino, C., Herculano, A.M., Jesuthasan, S., Wisenden, B., Bally-Cuif, L., Lange, M., Vernier, P., Norton, W., Tierney, K., Tropepe, V., and Neuhauss, S. (2012) Time to recognize zebrafish ‘affective’ behavior. Behaviour. 149:1019-1036

Mueller, K.P., Schnaedelbach, O.D., Russig, H.D., and Neuhauss, S.C. (2011) VisioTracker, an Innovative Automated Approach to Oculomotor Analysis. Journal of visualized experiments : JoVE. (56)

Huang, M., Chen, C.C., Huber-Reggi, S.P., Neuhauss, S.C., and Straumann, D. (2011) Comparison of infantile nystagmus syndrome in achiasmatic zebrafish and humans. Annals of the New York Academy of Sciences. 1233(1):285-291

Renninger, S.L., Schonthaler, H.B., Neuhauss, S.C., and Dahm, R. (2011) Investigating the genetics of visual processing, function and behaviour in zebrafish. Neurogenetics. 12(2):97-116

Renninger, S.L., Gesemann, M., and Neuhauss, S.C. (2011) Cone arrestin confers cone vision of high temporal resolution in zebrafish larvae. The European journal of neuroscience. 33(4):658-667

Maurer, C.M., Huang, Y.Y., and Neuhauss, S.C. (2011) Application of zebrafish oculomotor behavior to model human disorders. Reviews in the Neurosciences. 22(1):5-16

Neuhauss, S.C., Rico, E.P., and Gesemann, M. (2010) Nomenclature of glutamate transporters in zebrafish and other vertebrates. Brain research bulletin. 83(6):297

Tschopp, M., Takamiya, M., Cerveny, K.L., Gestri, G., Biehlmaier, O., Wilson, S.W., Strähle, U., and Neuhauss, S.C. (2010) Funduscopy in adult zebrafish and its application to isolate mutant strains with ocular defects. PLoS One. 5(11):e15427

Fleisch, V.C., and Neuhauss, S.C. (2010) Parallel visual cycles in the zebrafish retina. Progress in Retinal and Eye Research. 29(6):476-486

Gesemann, M., Maurer, C.M., and Neuhauss, S.C. (2010) Excitatory amino acid transporters in the zebrafish: Letter to "Expression and functional analysis of Na(+)-dependent glutamate transporters from zebrafish brain" from Rico et al. Brain research bulletin. 83(5):202-206

Maurer, C.M., Schönthaler, H.B., Mueller, K.P., and Neuhauss, S.C. (2010) Distinct retinal deficits in a zebrafish pyruvate dehydrogenase-deficient mutant. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(36):11962-11972

Huang, Y.Y., Tschopp, M., Straumann, D., and Neuhauss, S.C. (2010) Vestibular deficits do not underlie looping behavior in achiasmatic fish. Communicative & integrative biology. 3(4):379-381

Gesemann, M., Lesslauer, A., Maurer, C.M., Schönthaler, H.B., and Neuhauss, S.C. (2010) Phylogenetic analysis of the vertebrate excitatory/neutral amino acid transporter (SLC1/EAAT) family reveals lineage specific subfamilies. BMC Evolutionary Biology. 10:117

Schonthaler, H.B., Franz-Odendaal, T.A., Hodel, C., Gehring, I., Geisler, R., Schwarz, H., Neuhauss, S.C., and Dahm, R. (2010) The zebrafish mutant bumper shows a hyperproliferation of lens epithelial cells and fibre cell degeneration leading to functional blindness. Mechanisms of Development. 127(3-4):203-219

Haug, M.F., Biehlmaier, O., Mueller, K.P., and Neuhauss, S.C. (2010) Visual acuity in larval zebrafish: behavior and histology. Frontiers in Zoology. 7:8

Mueller, K.P., and Neuhauss, S.C. (2010) Behavioral Neurobiology: How Larval Fish Orient towards the Light. Current biology : CB. 20(4):R159-R161

Mueller, K.P., and Neuhauss, S.C. (2010) Quantitative Measurements of the Optokinetic Response in Adult Fish. Journal of Neuroscience Methods. 186(1):29-34

Froehlicher, M., Liedtke, A., Groh, K.J., Neuhauss, S.C., Segner, H., and Eggen, R.I. (2009) Zebrafish (Danio rerio) neuromast: Promising biological endpoint linking developmental and toxicological studies. Aquatic toxicology (Amsterdam, Netherlands). 95(4):307-319

Huang, Y.Y., Tschopp, M., and Neuhauss, S.C. (2009) Illusionary self-motion perception in zebrafish. PLoS One. 4(8):e6550

Froehlicher, M., Liedtke, A., Groh, K., Lopez-Schier, H., Neuhauss, S.C., Segner, H., and Eggen, R.I. (2009) Estrogen receptor subtype beta2 is involved in neuromast development in zebrafish (Danio rerio) larvae. Developmental Biology. 330(1):32-43

Fleisch, V.C., Schonthaler, H.B., von Lintig, J., and Neuhauss, S.C. (2008) Subfunctionalization of a retinoid-binding protein provides evidence for two parallel visual cycles in the cone-dominant zebrafish retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(33):8208-8216

Aleström, P., Begemann, G., Carvan, M.J. 3rd, Cheng, K.C., Crosier, K., Crosier, P., Ekker, S., Huttenlocher, A., Kawakami, K., Kelly, G., Korzh, V., Lieschke, G., Mione, M., Neely, M.N., Neuhauss, S., and Trede, N.S. (2008) Views on four key questions about zebrafish research. Zebrafish. 5(1):9-24

Huang, Y.Y., and Neuhauss, S.C. (2008) The optokinetic response in zebrafish and its applications. Frontiers in bioscience : a journal and virtual library. 13(1):1899-1916

Schonthaler, H.B., Fleisch, V.C., Biehlmaier, O., Makhankov, Y., Rinner, O., Bahadori, R., Geisler, R., Schwarz, H., Neuhauss, S.C., and Dahm, R. (2008) The zebrafish mutant lbk/vam6 resembles human multi-systemic disorders caused by aberrant trafficking of endosomal vesicles. Development (Cambridge, England). 135(2):387-399

Kallivretaki, E., Eggen, R.I., Neuhauss, S.C., Kah, O., and Segner, H. (2007) The zebrafish, brain-specific, aromatase cyp19a2 is neither expressed nor distributed in a sexually dimorphic manner during sexual differentiation. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(11):3155-3166

Schonthaler, H.B., Lampert, J.M., Isken, A., Rinner, O., Mader, A., Gesemann, M., Oberhauser, V., Golczak, M., Biehlmaier, O., Palczewski, K., Neuhauss, S.C., and von Lintig, J. (2007) Evidence for RPE65-independent vision in the cone-dominated zebrafish retina. The European journal of neuroscience. 26(7):1940-1949

Biehlmaier, O., Makhankov, Y., and Neuhauss, S.C. (2007) Impaired retinal differentiation and maintenance in zebrafish laminin mutants. Investigative ophthalmology & visual science. 48(6):2887-2894

Geisler, R., Rauch, G.J., Geiger-Rudolph, S., Albrecht, A., van Bebber, F., Berger, A., Busch-Nentwich, E., Dahm, R., Dekens, M.P., Dooley, C., Elli, A.F.,Gehring, I., Geiger, H., Geisler, M., Glaser, S., Holley, S., Huber, M., Kerr, A., Kirn, A., Knirsch, M., Konantz, M., Kuchler, A.M., Maderspacher, F., Neuhauss, S.C., Nicolson, T., Ober, E.A., Praeg, E., Ray, R., Rentzsch, B., Rick, J.M., Rief, E., Schauerte, H.E., Schepp, C.P., Schonberger, U., Schonthaler, H.B., Seiler, C., Sidi, S., Söllner, C., Wehner, A., Weiler, C., Nüsslein-Volhard, C. (2007) Large-scale mapping of mutations affecting zebrafish development. BMC Genomics. 8(1):11

Bahadori, R., Rinner, O., Schonthaler, H.B., Biehlmaier, O., Makhankov, Y.V., Rao, P., Jagadeeswaran, P., and Neuhauss, S.C. (2006) The Zebrafish fade out Mutant: A Novel Genetic Model for Hermansky-Pudlak Syndrome. Investigative ophthalmology & visual science. 47(10):4523-4531

Huang, Y.Y., Rinner, O., Hedinger, P., Liu, S.C., and Neuhauss, S.C. (2006) Oculomotor instabilities in zebrafish mutant belladonna: a behavioral model for congenital nystagmus caused by axonal misrouting. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(39):9873-9880

Bahadori, R., Biehlmaier, O., Zeitz, C., Labhart, T., Makhankov, Y.V., Forster, U., Gesemann, M., Berger, W., and Neuhauss, S.C. (2006) Nyctalopin is essential for synaptic transmission in the cone dominated zebrafish retina. The European journal of neuroscience. 24(6):1664-1674

Kallivretaki, E., Eggen, R., Neuhauss, S., Alberti, M., Kausch, U., and Segner, H. (2006) Aromatase in zebrafish: A potential target for endocrine disrupting chemicals. Marine Environmental Research. 62 Suppl 1:S187-90

Hodel, C., Neuhauss, S.C., and Biehlmaier, O. (2006) Time course and development of light adaptation processes in the outer zebrafish retina. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology. 288(6):653-662

Ninkovic, J., Folchert, A., Makhankov, Y.V., Neuhauss, S.C., Sillaber, I., Straehle, U., and Bally-Cuif, L. (2006) Genetic identification of AChE as a positive modulator of addiction to the psychostimulant D-amphetamine in zebrafish. Journal of neurobiology. 66(5):463-475

Seth, A., Culverwell, J., Walkowicz, M., Toro, S., Rick, J.M., Neuhauss, S.C., Varga, Z.M., and Karlstrom, R.O. (2006) belladonna/(lhx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain. Development (Cambridge, England). 133(4):725-735

Fleisch, V.C., and Neuhauss, S.C.F. (2006) Visual Behavior in Zebrafish. Zebrafish. 3(2):191-201

Schonthaler, H.B., Lampert, J.M., von Lintig, J., Schwarz, H., Geisler, R., and Neuhauss, S.C. (2005) A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision. Developmental Biology. 284(2):421-436

Rinner, O., Makhankov, Y.V., Biehlmaier, O., and Neuhauss, S.C. (2005) Knockdown of Cone-Specific Kinase GRK7 in Larval Zebrafish Leads to Impaired Cone Response Recovery and Delayed Dark Adaptation. Neuron. 47(2):231-242

Seiler, C., Finger-Baier, K.C., Rinner, O., Makhankov, Y.V., Schwarz, H., Neuhauss, S.C., and Nicolson, T. (2005) Duplicated genes with split functions: independent roles of protocadherin15 orthologues in zebrafish hearing and vision. Development (Cambridge, England). 132(3):615-623

Trueb, B., Neuhauss, S.C., Baertschi, S., Rieckmann, T., Schild, C., and Taeschler, S. (2005) Fish possess multiple copies of fgfrl1, the gene for a novel FGF receptor. BBA Gene Structure and Expression. 1727(1):65-74

Rinner, O., Rick, J.M., and Neuhauss, S.C. (2005) Contrast sensitivity, spatial and temporal tuning of the larval zebrafish optokinetic response. Investigative ophthalmology & visual science. 46(1):137-142

Makhankov, Y.V., Rinner, O., and Neuhauss, S.C. (2004) An inexpensive device for non-invasive electroretinography in small aquatic vertebrates. Neurosci. Methods. 135(1-2):205-210

Biehlmaier, O., Neuhauss, S.C.F., and Kohler, K. (2003) Synaptic plasticity and functionality at the cone terminal of the developing zebrafish retina. Journal of neurobiology. 56(3):222-236

Bahadori, R., Huber, M., Rinner, O., Seeliger, M.W., Geiger-Rudolph, S., Geisler, R., and Neuhauss, S.C. (2003) Retinal function and morphology in two zebrafish models of oculo-renal syndromes. The European journal of neuroscience. 18(6):1377-1386

Neuhauss, S.C., Seeliger, M.W., Schepp, C.P., and Biehlmaier, O. (2003) Retinal defects in the zebrafish bleached mutant. Documenta ophthalmologica. Advances in ophthalmology. 107(1):71-78

Biehlmaier, O., Neuhauss, S.C., and Kohler, K. (2003) Double cone dystrophy and RPE degeneration in the retina of the zebrafish gnn mutant. Investigative ophthalmology & visual science. 44(3):1287-1298

Neuhauss, S.C. (2003) Behavioral genetic approaches to visual system development and function in zebrafish. Journal of neurobiology. 54(1):148-160

Seeliger, M.W., Rilk, A., and Neuhauss, S.C.F. (2002) Ganzfeld ERG in zebrafish larvae. Documenta ophthalmologica. Advances in ophthalmology. 104(1):57-68

Biehlmaier, O., Neuhauss, S.C.F., and Kohler, K. (2001) Onset and time course of apoptosis in the developing zebrafish retina. Cell and tissue research. 306:199-207

Gnuegge, L., Schmid, S., and Neuhauss, S.C.F. (2001) Analysis of the activity-deprived zebrafish mutant macho reveals an essential requirement of neuronal activity for the development of a fine-grained visuotopic map. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(10):3542-3548

Biehlmaier, O., Neuhauss, S.C.F., and Kohler, K. (2001) Onset and time course of apoptosis in the developing retina of zebrafish. Investigative ophthalmology & visual science. 42(4):3407

Rick, J.M., Horschke, I., and Neuhauss, S.C. (2000) Optokinetic behavior is reversed in achiasmatic mutant zebrafish larvae. Current biology : CB. 10(10):595-598

Biehlmaier, O., Neuhauss, S.C.F., Werts, D., and Kohler, K. (2000) Visual mutant zebrafish express morphological abnormalities during retinal development. The European journal of neuroscience. 12:487

Neuhauss, S.C.F., Biehlmaier, O., Seeliger, M.W., Das, T., Kohler, K., Harris, W.A., and Baier, H. (1999) Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(19):8603-8615

Geisler, R., Rauch, G.J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M.P., Finger, K., Fricke, C., Gates, M.A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnugge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson, T., Pelegri, F., Ray, R., Rick, J.M., Roehl, H., Roeser, T., Schauerte, H.E., Schier, A.F., Schönberger, U., Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W.S., Weiler, C., Nüsslein-Volhard, C., and Haffter, P. (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics. 23(1):86-89

Drummond, I.A., Majumdar, A., Hentschel, H., Elger, M., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Stemple, D.L., Zwartkruis, F., Rangini, Z., Driever, W., and Fishman, M.C. (1998) Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (Cambridge, England). 125:4655-4667

Marlow, F., Zwartkruis, F., Malicki, J., Neuhauss, S.C.F., Abbas, L., Weaver, M., Driever, W., and Solnica-Krezel, L. (1998) Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish. Developmental Biology. 203:382-399

Knapik, E.W., Goodman, A., Ekker, M., Chevrette, M., Delgado, J., Neuhauss, S., Shimoda, N., Driever, W., Fishman, M.C., and Jacob, H.J. (1998) A microsatellite genetic linkage map for zebrafish (Danio rerio). Nature Genetics. 18:338-343

Seeliger, M., Neuhauss, S.C.F., Kohler, K., and Zrenner, E. (1998) Ganzfeld electroretinography in the zebrafish (Danio rerio). Investigative ophthalmology & visual science. 39:975

Talbot, W.S., Egan, E.S., Gates, M.A., Walker, C., Ullmann, B., Neuhauss, S.C.F., Kimmel, C.B., and Postlethwait, J.H. (1998) Genetic analysis of chromosomal rearrangements in the cyclops region of the zebrafish genome. Genetics. 148:373-380

Schier, A.F., Neuhauss, S.C.F., Helde, K.A., Talbot, W.S., and Driever, W. (1997) The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development (Cambridge, England). 124(2):327-342

Abdelilah, S., Mountcastle-Shah, E., Harvey, M., Solnica-Krezel, L., Schier, A.F., Stemple, D.L., Malicki, J., Neuhauss, S.C., Zwartkruis, F., Stainier, D.Y., Rangini, Z., and Driever, W. (1996) Mutations affecting neural survival in the zebrafish Danio rerio. Development (Cambridge, England). 123:217-227

Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C. (1996) A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123:37-46

Malicki, J., Neuhauss, S.C., Schier, A.F., Solnica-Krezel, L., Stemple, D.L., Stainier, D.Y., Abdelilah, S., Zwartkruis, F., Rangini, Z., and Driever, W. (1996) Mutations affecting development of the zebrafish retina. Development (Cambridge, England). 123:263-273

Malicki, J., Schier, A.F., Solnica-Krezel, L., Stemple, D.L., Neuhauss, S.C., Stainier, D.Y., Abdelilah, S., Rangini, Z., Zwartkruis, F., and Driever, W. (1996) Mutations affecting development of the zebrafish ear. Development (Cambridge, England). 123:275-283

Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Abdelilah, S., Stainier, D.Y., and Driever, W. (1996) Mutations affecting craniofacial development in zebrafish. Development (Cambridge, England). 123:357-367

Pack, M., Solnica-Krezel, L., Malicki, J., Neuhauss, S.C., Schier, A-, F., Stemple, D.L., Driever, W., and Fishman, M.C. (1996) Mutations affecting development of zebrafish digestive organs. Development (Cambridge, England). 123:321-328

Schier, A.F., Neuhauss, S.C., Harvey, M., Malicki, J., Solnica-Krezel, L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Stemple, D.L., Rangini, Z., Yang, H., and Driever, W. (1996) Mutations affecting the development of the embryonic zebrafish brain. Development (Cambridge, England). 123:165-178

Solnica-Krezel, L., Stemple, D.L., Mountcastle-Shah, E., Rangini, Z., Neuhauss, S.C., Malicki, J., Schier, A.F., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., and Driever, W. (1996) Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development (Cambridge, England). 123:67-80

Stainier, D.Y., Fouquet, B., Chen, J.N., Warren, K.S., Weinstein, B.M., Meiler, S.E., Mohideen, M.A., Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Driever, W., and Fishman, M.C. (1996) Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123:285-292

Stemple, D.L., Solnica-Krezel, L., Zwartkruis, F., Neuhauss, S.C., Schier, A.F., Malicki, J., Stainier, D.Y., Abdelilah, S., Rangini, Z., Mountcastle-Shah, E., and Driever, W. (1996) Mutations affecting development of the notochord in zebrafish. Development (Cambridge, England). 123:117-128

Yelick, P.C., Driever, W., Neuhauss, S., and Stashenko, P. (1996) Craniofacial cartilage development in zebrafish. Annals of the New York Academy of Sciences. 785:360-361

Abdelilah, S.,Driever, W., Gorn, A., Malicki,J., Neuhauss, S., Pack, M., Rangini, Z., Schier, A., Solnica-Krezel, L., Stanier, D., and Stemple, D. (1996) Anatomy of the 24, 48, 72 and 120 hours Zebrafish (Danio rerio) Embryo. ZFIN Direct Data Submission.

Brockerhoff, S.E., Hurley, J.B., Janssen-Bienhold, U., Neuhauss, S.C.F., Driever, W., and Dowling, J.E. (1995) A behavioral screen for isolating zebrafish mutants with visual system defects. Proceedings of the National Academy of Sciences of the United States of America. 92:10545-10549

Neuhauss, S. (1992) Early development of germ cells and alkaline phosphatase activity in zebrafish embryos. Master's Thesis.