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Figure 7.

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Gan et al., 2026 - COMMD9-regulated endothelial cell abnormality-induced hypercoagulability is associated with Budd-Chiari syndrome
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Figure 7.

Commd9 knockdown exacerbates venous hypercoagulability induced by flow restriction in vivo. (A) Flowchart of animal experiments. (B) Representative images of thrombi induced by IVC ligation after Commd9 inhibition using adeno-associated viral vector serotype-9 (AAV9). Thrombus lengths and weights were measured (right panel, N = 6 per group). (C, D) Immunostaining of IVC tissue sections for fibronectin (C) and integrin alpha 2b (D). Scale bar, 100 μm. The results are shown as mean ± SD, ***P < 0.001; **P < 0.01; *P < 0.05.

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