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ID: ZDB-IMAGE-260423-46
Publication: Wei et al., 2026 - A Novel CRYBB2 Splicing Mutation Is Associated With Lens Extracellular Matrix Remodeling and Vascular Alterations in Congenital Cataract
All Figures: Figures for Wei et al., 2026

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Figure 2.

Characterization of WT and crybb2^+/− zebrafish larvae. (A) Stereomicroscopic imaging of WT and crybb2^+/− zebrafish eyes at 6 dpf. Images were captured using a Leica M205 FA stereomicroscope. (B) Measurements of eye and lens diameters and their ratios to body length in zebrafish larvae at 6 dpf. Quantification was performed on 10 larvae per group. Images were processed and analyzed using ImageJ software. (C) Survival analysis of WT and crybb2^+/− larvae from 1 to 20 dpf. Survival curves were plotted and analyzed using GraphPad Prism 8 with the Kaplan-Meier method. (D) Representative locomotor trajectories of zebrafish larvae at 7 dpf. (E) Quantitative analysis of locomotor activity at 7 dpf, including traveled distance, swimming speed, maximum acceleration, activity states, and resting time. Behavioral tracking was conducted using EthoVision XT software (Noldus Information Technology, Leesburg, VA, USA).

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