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Fig. 6 Effect of MYDGF knockdown on HSF1 expression after ONI. MYDGF-specific MO or MYDGF-specific sgRNA injections via the CRISPR/Cas9 system. (a) Knockdown with MYDGF-specific MO (MYDGF-MO) and (b) MYDGF-specific sgRNA injections using the CRISPR/Cas9 system (MYDGF/Cas9) markedly reduced HSF1 mRNA expression in the retina 6 h after ONI. Statistical analysis was performed using one-way ANOVAs, followed by Scheffe’s multiple-comparison tests. Data are expressed as the means ± SEMs (n = 5–6), with statistical significance set at * p < 0.05.
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Full text @ Int. J. Mol. Sci.