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Figure Caption
Fig. 3 CRISPR/Cas9-mediated genome editing of the rbm24b locus. (A) The genomic organization of rbm24b locus. The guide RNA targeting sequence in the first exon (E1) is underlined, and the PAM sequence is shown in blue. (B) Deletion of eight nucleotides and insertion of 15 nucleotides (red) in the targeted region. (C) Schema of Rbm24b protein domains and alignment of amino acids between wild-type and mutated Rbm24b proteins.The triangles indicate the position where amino acid change occurs or the last amino acid in the mutated Rbm24b protein.
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