ZFIN Image: Munro et al., 2025, Figure 1

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Figure Caption

Figure 1

Mutagenesis of zebrafish rrm2b –. (A) Summary schematic depicting the rrm2b sgRNA target site on exon 3 of the zebrafish rrm2b gene. (B) DNA and corresponding peptide sequence of WT zebrafish rrm2b and mutant zebrafish rrm2b^∆26bp. Red = mutation, ^* = premature stop codon. (C) Immunoblotting of Rrm2b and alpha tubulin in rrm2b^+/+ and rrm2b^−/− in 5 dpf tail muscle. N = 10 larvae tails each. D. Quantification of Rrm2b immunoblotting relative to alpha tubulin.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.