ZFIN Image: Liu et al., 2024, Fig. 2

Image

Figure Caption

Fig. 2 RES has a mitigating effect on VPH-induced HF in zebrafish. (A) Hearts of zebrafish under bright field condition (left panel); confocal microscopy (middle panel); top view with fluorescence (cmlc2:EGFP) superimposed on bright field (right panel). (B) Under 80 μM VPH exposure, the pericardial cavity area of zebrafish in the 40 μM RES group was significantly reduced relative to the heart failure group. (C) Under 80 μM VPH exposure, the angle of cardiac looping in zebrafish in the 40 μM RES group tended to normalise compared to the heart failure group. (D) Under 80 μM VPH exposure, there was a significant recovery of zebrafish blood flow rate in the 40 μM RES group relative to the heart failure group. (Compared with the control group: *: P < 0.05, **: P < 0.05, ***: P < 0.001, ****: P < 0.0001, NS: not statistically different).

Acknowledgments

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