ZFIN Image: Tarbashevich et al., 2023, FIGURE 3

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Figure Caption

FIGURE 3

MZsod2 KO embryos exhibit reduction in the germ cell migration speed. (A) The scheme of crosses and genotypes analyzed in this manuscript. (B, C) PGC migration speed was determined by tracking cell migration for 70 min using Imaris software. (D) Normalized PGC cluster lengths at 24 hpf in WT and MZsod2 KO embryos treated with neomycin (enhanced ROS production condition). (E, F) Representative images of embryos analyzed for the PGC cluster length (quantification shown in (D)) ****p < 0.0001, *p < 0.05 was determined by Student’s t-test. n - number of PGCs analyzed in 38 WT and 36 MZsod2 KO embryos (B), 24 MZsod2 KO + control (contr) mRNA and 29 MZsod2 KO + sod2 mRNA embryos (C). N - number of PGC clusters (one cluster per embryo) analyzed.

Acknowledgments

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