Fig. 1.

Fig. 1.

Expression patterns of pax3 and pax7 in medaka. (A-E″) Expression of pax3b mRNA was detected in NCCs at stage 22 (9 somite embryo) (A-A″, between arrowheads), whereas pax7a expression was observed in migrating NCCs anteroventral to the pax3b-expressing premigratory NCCs (B-B″; panels on the right show enlarged views; pax7a-expressing cells are indicated by arrows). The pax3b expression had shifted posteriorly at stage 25 (18-19 somite embryo) (C,C′, between arrowheads) and became undetectable by stage 27 (24 somite embryo) (not shown). pax7a mRNA was continuously observed in migrating NCCs from stage 25 to stage 27 (indicated by arrows; see also Fig. S2). pax3b and pax7a mRNAs were expressed in similar regions of neural tissue and somites (A-E). Expression of pax3b was observed in several anterior somites at stage 22 (A), shifted to posterior somites at stage 25 (C; see also Fig. S2), and appeared to precede that of pax7a in somites (B,D). The time windows of pax3b and pax7a expression overlapped during stages 22-25. (A-E) Lateral views. (A′-E′,A″,B″,D″,E″) Dorsal views. Images are representative of more than ten embryos. Scale bar: 250 µm.