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Fig. 2
Knockout of miR-184 led to microphthalmia in zebrafish. (A) The gross development and growth were normal in embryonic WT and miR-184−/− zebrafish. (B) Microphthalmia is observed in adult WT and miR-184−/− zebrafish. (C and D) The eye diameters were significantly reduction in 2-week- (n = 15) and 2-month-old (n = 24) miR-184−/− zebrafish. Student t-test was used for statistical analysis, ***p < .001. (E and F) Except for microphthalmia, no other eye abnormities were observed in 1-month- and 2-month-old WT and miR-184−/− zebrafish histological sections. Bar, 100 μm.
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