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Fig. 10
geo77 also affects the length of ISVs. (A–G) Fluorescence microscopy images of representative Tg(kdrl:gfp) embryos treated from 24 hpf, and DMSO-treated control at 72 hpf. Yellow arrows indicate sections of ISVs with decreased length angiogenesis. Scale bar, 100 μm. (H) Estimated and presented total lengths of 8 ISVs per embryo. Compound geo77 (1.3 μM) shows statistically significant inhibition on the total length of ISVs, while the other tested compounds show a non-significant trend at the tested concentrations. Data are expressed as mean ± SD (n = 4–7/group). ** p < 0.05.
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