IMAGE

Fig. 1

ID: ZDB-IMAGE-230617-8
Publication: Sun et al., 2023 - hapln1a⁺ cells guide coronary growth during heart morphogenesis and regeneration
All Figures: Figures for Sun et al., 2023

Image

Figure Caption

Fig. 1 Single-cell RNA-sequencing reveals hapln1a+ epicardial clusters are enriched with angiogenesis factors during coronary vascularization.

a Uniform manifold approximation and projection (UMAP) clustering of tcf21⁺ single-cells from juvenile hearts. b Heatmap of the top 10 markers for epicardial cells from juvenile tcf21:nucEGFP hearts. c Identification of epicardial cell clusters based on gene ontology analysis. d Feature plot of hapln1a expression in epicardial clusters of juvenile hearts. e Heatmap of gene ontology enrichment for tcf21⁺/hapln1a⁺ epicardial cells vs. tcf21⁺/hapln1a^- cells. f Log₂-fold-change vs. abundance of normalized gene expression of tcf21⁺/hapln1a⁺ epicardial cells vs. tcf21⁺/hapln1a^- cells. Each point designates a unique gene; differentially expressed unique genes are in red. Unique genes with higher expression in tcf21⁺/hapln1a⁺ epicardial cells have positive fold-change values, whereas unique genes with higher expression in tcf21⁺/hapln1a^- cells have negative fold-change values.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.