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Publication: Zhang et al., 2023 - SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway
All Figures: Figures for Zhang et al., 2023

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Fig. 1

SARS-CoV-2 S-protein inhibits ARPE-19 cell proliferation in vitro. A Immunoblot of ACE2 and β-actin in ARPE-19 or HA-ACE2-overexpressed ARPE-19 cells. B Real-time cell analyzer (RTCA) detection of cell proliferation of ARPE-19 cells (wt), S-protein-treated ARPE-19 cells (B), or Flag-S overexpressed ARPE-19 cells (D). C and E Flow cytometry measurement of the cell cycle of ARPE-19 cells (wt), S-protein-treated ARPE-19 cells (+ S-protein), or Flag-S-overexpressed ARPE-19 cells (Flag-S). The black, gray and blank rectangles represent G1, S, and G2 phases respectively. The data represent mean ± SD, n = 3. Unpaired Student’s T-test was used for statistical analysis. *p < 0.05

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